CRCGN013_HEPG2_24H:K10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vorinostat 2.5 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

900 genes differentially expressed following the CRCGN013_HEPG2_24H:K10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FOXO4 forkhead box O4 9.52189
ALDOC aldolase C, fructose-bisphosphate 9.24519
DNM1 dynamin 1 9.19938
TAC4 tachykinin 4 (hemokinin) 9.15092
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 8.72321
SKIC2 SKI2 subunit of superkiller complex 8.67887
UBE2L6 ubiquitin-conjugating enzyme E2L 6 8.59799
ZDHHC6 zinc finger, DHHC-type containing 6 8.35143
NR1H2 nuclear receptor subfamily 1, group H, member 2 8.16818
CBR1 carbonyl reductase 1 7.89679
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 7.87686
STX1A syntaxin 1A (brain) 7.65381
H2BC12 H2B clustered histone 12 7.05141
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 6.91443
HMG20B high mobility group 20B 6.88349
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 6.69662
TBC1D10C TBC1 domain family, member 10C 6.3987
STXBP1 syntaxin binding protein 1 6.36072
LGMN legumain 6.276
HMOX1 heme oxygenase 1 5.60632
PTPN1 protein tyrosine phosphatase, non-receptor type 1 5.41317
LSR lipolysis stimulated lipoprotein receptor 5.30428
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 5.2709
CIAO3 cytosolic iron-sulfur assembly component 3 5.15163
AMDHD2 amidohydrolase domain containing 2 5.14882
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 5.04711
GSTZ1 glutathione S-transferase zeta 1 5.03684
TIMP2 TIMP metallopeptidase inhibitor 2 4.933
PLS1 plastin 1 4.84437
USP6NL USP6 N-terminal like 4.79117
DUSP6 dual specificity phosphatase 6 4.76903
MCOLN1 mucolipin 1 4.76433
MAP7 microtubule-associated protein 7 4.73714
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.71755
CCND3 cyclin D3 4.63071
PRKCD protein kinase C, delta 4.42846
TMEM50A transmembrane protein 50A 4.41845
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.38898
CARMIL1 capping protein regulator and myosin 1 linker 1 4.35689
PLA2G15 phospholipase A2, group XV 4.30832
ANO10 anoctamin 10 4.30591
STIMATE STIM activating enhancer 4.28486
MVP major vault protein 4.18151
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.13541
ALAS1 5'-aminolevulinate synthase 1 4.08072
BPHL biphenyl hydrolase-like (serine hydrolase) 3.94932
PPARD peroxisome proliferator-activated receptor delta 3.92308
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 3.90444
MYC v-myc avian myelocytomatosis viral oncogene homolog 3.88902
COG7 component of oligomeric golgi complex 7 3.84333
NIT1 nitrilase 1 3.83303
CALM3 calmodulin 3 (phosphorylase kinase, delta) 3.80598
AARS1 alanyl-tRNA synthetase 1 3.71396
H2BC21 H2B clustered histone 21 3.69619
ABHD4 abhydrolase domain containing 4 3.6811
RSU1 Ras suppressor protein 1 3.64269
GRN granulin 3.63385
TERF2IP telomeric repeat binding factor 2, interacting protein 3.60838
LRP10 low density lipoprotein receptor-related protein 10 3.57436
TMCO1 transmembrane and coiled-coil domains 1 3.55948
ABHD6 abhydrolase domain containing 6 3.5416
VAT1 vesicle amine transport 1 3.5264
CYTH1 cytohesin 1 3.52345
INTS3 integrator complex subunit 3 3.51875
MYLIP myosin regulatory light chain interacting protein 3.50679
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 3.50086
TCEA2 transcription elongation factor A (SII), 2 3.48636
KDM3A lysine (K)-specific demethylase 3A 3.48139
IGFBP3 insulin-like growth factor binding protein 3 3.47418
BORCS6 BLOC-1 related complex subunit 6 3.46772
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 3.44329
CCDC28A coiled-coil domain containing 28A 3.41692
STXBP2 syntaxin binding protein 2 3.39744
ZFP36 ZFP36 ring finger protein 3.38486
CAB39 calcium binding protein 39 3.37941
FKBPL FK506 binding protein like 3.33292
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 3.32878
MNAT1 MNAT CDK-activating kinase assembly factor 1 3.32277
TBPL1 TBP-like 1 3.30447
BACE2 beta-site APP-cleaving enzyme 2 3.30183
MBOAT7 membrane bound O-acyltransferase domain containing 7 3.29454
TCF15 transcription factor 15 (basic helix-loop-helix) 3.27278
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.25717
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 3.23182
CNPY4 canopy FGF signaling regulator 4 3.22406
ARFIP2 ADP-ribosylation factor interacting protein 2 3.21699
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 3.2166
SPEG SPEG complex locus 3.21287
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.21261
MAPK3 mitogen-activated protein kinase 3 3.20749
HDAC7 histone deacetylase 7 3.14382
HLA-DRA major histocompatibility complex, class II, DR alpha 3.1419
KIAA0319L KIAA0319-like 3.1411
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 3.12653
ZNF205 zinc finger protein 205 3.12194
ITGA7 integrin, alpha 7 3.11716
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 3.07516
KCTD17 potassium channel tetramerization domain containing 17 3.05091
DIPK1A divergent protein kinase domain 1A 3.05073
ARF3 ADP-ribosylation factor 3 3.05063
KIF5C kinesin family member 5C 3.03571
COG2 component of oligomeric golgi complex 2 3.02052
CLEC16A C-type lectin domain family 16, member A 3.01425
WLS wntless Wnt ligand secretion mediator 3.00055
RND1 Rho family GTPase 1 2.99321
RAB11FIP1 RAB11 family interacting protein 1 (class I) 2.98522
CYB561 cytochrome b561 2.98396
ZBTB22 zinc finger and BTB domain containing 22 2.97048
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 2.94609
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 2.94539
CCDC92 coiled-coil domain containing 92 2.94318
CASP9 caspase 9, apoptosis-related cysteine peptidase 2.94242
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.93873
SYP synaptophysin 2.93172
IFI6 interferon, alpha-inducible protein 6 2.93078
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 2.91451
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.91446
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 2.91237
PPP4C protein phosphatase 4, catalytic subunit 2.91235
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) 2.91103
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 2.90903
UNC93B1 unc-93 homolog B1 (C. elegans) 2.90763
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 2.9072
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 2.90551
IQCC IQ motif containing C 2.9036
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 2.89901
ARHGAP29 Rho GTPase activating protein 29 2.89796
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.89794
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 2.89402
DCAF10 DDB1 and CUL4 associated factor 10 2.88848
ELAVL3 ELAV like neuron-specific RNA binding protein 3 2.88766
RBKS ribokinase 2.88631
ADRA2C adrenoceptor alpha 2C 2.88423
BBC3 BCL2 binding component 3 2.88235
WDR19 WD repeat domain 19 2.87222
PTPN12 protein tyrosine phosphatase, non-receptor type 12 2.87024
SLC25A44 solute carrier family 25, member 44 2.8653
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 2.86234
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.8583
SFTPB surfactant protein B 2.83472
TLE6 transducin-like enhancer of split 6 2.82489
ICAM1 intercellular adhesion molecule 1 2.81824
MRNIP MRN complex interacting protein 2.81594
RASA4 RAS p21 protein activator 4 2.81255
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 2.81194
FAM110D family with sequence similarity 110, member D 2.80963
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 2.80938
BIN3 bridging integrator 3 2.80299
TUBB2B tubulin, beta 2B class IIb 2.79927
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 2.79666
GNS glucosamine (N-acetyl)-6-sulfatase 2.79141
NAPSA napsin A aspartic peptidase 2.79095
LIG4 ligase IV, DNA, ATP-dependent 2.79031
GPR162 G protein-coupled receptor 162 2.78239
SNPH syntaphilin 2.77797
MXI1 MAX interactor 1, dimerization protein 2.77724
TUFT1 tuftelin 1 2.77611
SETD3 SET domain containing 3 2.77189
METTL25B methyltransferase like 25B 2.77102
RB1CC1 RB1-inducible coiled-coil 1 2.76503
WDR25 WD repeat domain 25 2.75819
CCDC71 coiled-coil domain containing 71 2.75691
H1-2 H1.2 linker histone, cluster member 2.75635
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.7533
UBE3C ubiquitin protein ligase E3C 2.75148
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.74434
DDB2 damage-specific DNA binding protein 2, 48kDa 2.74368
HDAC5 histone deacetylase 5 2.74249
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 2.74068
CYTH3 cytohesin 3 2.73686
H2BC5 H2B clustered histone 5 2.73102
RIGI RNA sensor RIG-I 2.72777
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.72706
ROM1 retinal outer segment membrane protein 1 2.72289
TXNRD1 thioredoxin reductase 1 2.72182
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.7212
PTMS parathymosin 2.71646
CD9 CD9 molecule 2.71461
H2AC6 H2A clustered histone 6 2.71278
SETD1A SET domain containing 1A 2.71215
PLCH2 phospholipase C, eta 2 2.70918
SORBS3 sorbin and SH3 domain containing 3 2.70872
GPATCH1 G patch domain containing 1 2.70427
TRAPPC6A trafficking protein particle complex 6A 2.70094
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 2.69947
PLPPR2 phospholipid phosphatase related 2 2.69552
ZCCHC14 zinc finger, CCHC domain containing 14 2.69163
DZANK1 double zinc ribbon and ankyrin repeat domains 1 2.69078
ZNF646 zinc finger protein 646 2.68891
NPR1 natriuretic peptide receptor 1 2.68146
SCPEP1 serine carboxypeptidase 1 2.68097
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 2.67329
TARBP1 TAR (HIV-1) RNA binding protein 1 2.66995
ARL3 ADP-ribosylation factor-like 3 2.66936
RTN2 reticulon 2 2.66705
TRAFD1 TRAF-type zinc finger domain containing 1 2.66391
TUSC2 tumor suppressor candidate 2 2.66287
RHOT2 ras homolog family member T2 2.65846
TXNL4B thioredoxin-like 4B 2.64325
BAMBI BMP and activin membrane-bound inhibitor 2.63928
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 2.63897
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 2.61308
SNN stannin 2.60098
HPS5 Hermansky-Pudlak syndrome 5 2.60097
MSRA methionine sulfoxide reductase A 2.59549
RNF170 ring finger protein 170 2.59353
ACBD4 acyl-CoA binding domain containing 4 2.58661
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2.58646
EGR1 early growth response 1 2.57699
IFI44L interferon-induced protein 44-like 2.57383
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 2.5724
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 2.5721
GABARAPL2 GABA(A) receptor-associated protein-like 2 2.57071
USP18 ubiquitin specific peptidase 18 2.56968
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.56167
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 2.56151
CYCS cytochrome c, somatic 2.56085
NRBF2 nuclear receptor binding factor 2 2.55921
SCGB1D1 secretoglobin, family 1D, member 1 2.55888
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.55875
LIN37 lin-37 DREAM MuvB core complex component 2.55739
CDPF1 cysteine-rich, DPF motif domain containing 1 2.55423
NOSIP nitric oxide synthase interacting protein 2.55289
TUBD1 tubulin, delta 1 2.55214
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 2.55064
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 2.54212
INTS5 integrator complex subunit 5 2.53865
PRUNE1 prune exopolyphosphatase 1 2.53401
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.53381
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 2.53234
ZNF696 zinc finger protein 696 2.53049
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 2.52807
CLDN3 claudin 3 2.52708
CGRRF1 cell growth regulator with ring finger domain 1 2.52678
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 2.52428
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 2.51363
PTP4A3 protein tyrosine phosphatase type IVA, member 3 2.50772
DENND2D DENN/MADD domain containing 2D 2.50362
SIRPA signal-regulatory protein alpha 2.50011
CALHM2 calcium homeostasis modulator 2 2.49278
KIF16B kinesin family member 16B 2.48973
EFNA3 ephrin-A3 2.48946
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 2.48885
ATG2A autophagy related 2A 2.48721
CHMP1A charged multivesicular body protein 1A 2.48534
TRIM62 tripartite motif containing 62 2.475
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 2.46839
PEX11B peroxisomal biogenesis factor 11 beta 2.46556
FUZ fuzzy planar cell polarity protein 2.46419
HPSE heparanase 2.46362
NME7 NME/NM23 family member 7 2.46103
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.46088
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 2.46015
CLPTM1 cleft lip and palate associated transmembrane protein 1 2.45994
MDH1 malate dehydrogenase 1, NAD (soluble) 2.45971
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 2.44494
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 2.44316
PAIP2B poly(A) binding protein interacting protein 2B 2.43908
ERC1 ELKS/RAB6-interacting/CAST family member 1 2.43715
MOSPD3 motile sperm domain containing 3 2.43518
DPF1 D4, zinc and double PHD fingers family 1 2.43516
TMEM121 transmembrane protein 121 2.43258
ACP5 acid phosphatase 5, tartrate resistant 2.42752
MTCH1 mitochondrial carrier 1 2.42097
RBBP5 retinoblastoma binding protein 5 2.41232
TUFM Tu translation elongation factor, mitochondrial 2.4097
RPA3 replication protein A3, 14kDa 2.40935
MMUT methylmalonyl-CoA mutase 2.40859
TRADD TNFRSF1A-associated via death domain 2.40769
ROGDI rogdi homolog (Drosophila) 2.40764
UGDH UDP-glucose 6-dehydrogenase 2.40701
ABHD8 abhydrolase domain containing 8 2.40562
HINFP histone H4 transcription factor 2.40315
C15ORF38-AP3S2 C15orf38-AP3S2 readthrough 2.39853
PINK1 PTEN induced putative kinase 1 2.39367
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) 2.39261
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 2.39113
LDHC lactate dehydrogenase C 2.38958
FOXO3 forkhead box O3 2.38557
SH2B1 SH2B adaptor protein 1 2.38066
RUNDC3B RUN domain containing 3B 2.37652
FASTKD5 FAST kinase domains 5 2.37424
GSTM2 glutathione S-transferase mu 2 (muscle) 2.37221
WHR1 winged helix repair factor 1 2.3696
REEP2 receptor accessory protein 2 2.36658
CORO1A coronin, actin binding protein, 1A 2.36624
H2BC9 H2B clustered histone 9 2.36548
STAT2 signal transducer and activator of transcription 2, 113kDa 2.36119
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 2.36004
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 2.3584
FBXO2 F-box protein 2 2.35782
TPMT thiopurine S-methyltransferase 2.35046
MACO1 macoilin 1 2.34729
FABP3 fatty acid binding protein 3, muscle and heart 2.3461
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.34463
YPEL5 yippee-like 5 (Drosophila) 2.34383
SEPHS2 selenophosphate synthetase 2 2.34382
RASAL2 RAS protein activator like 2 2.34274
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.3419
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 2.34108
CABP1 calcium binding protein 1 2.33917
LCMT1 leucine carboxyl methyltransferase 1 2.33647
HLA-E major histocompatibility complex, class I, E 2.33514
TWF2 twinfilin actin binding protein 2 2.33176
BCAM basal cell adhesion molecule (Lutheran blood group) 2.3256
AKAP8L A kinase (PRKA) anchor protein 8-like 2.32553
PRSS53 protease, serine, 53 2.3252
DKKL1 dickkopf-like 1 2.32493
ATG4B autophagy related 4B, cysteine peptidase 2.32347
SFXN3 sideroflexin 3 2.32306
CHMP5 charged multivesicular body protein 5 2.31855
GDI1 GDP dissociation inhibitor 1 2.3178
OSTF1 osteoclast stimulating factor 1 2.31748
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 2.31337
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 2.31292
CTR9 CTR9, Paf1/RNA polymerase II complex component 2.30799
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 2.30776
PTAFR platelet-activating factor receptor 2.30689
CALCOCO1 calcium binding and coiled-coil domain 1 2.30627
MAPRE3 microtubule-associated protein, RP/EB family, member 3 2.30411
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 2.29822
AMN amnion associated transmembrane protein 2.29786
SHARPIN SHANK-associated RH domain interactor 2.29569
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 2.29539
GLCE glucuronic acid epimerase 2.29252
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 2.29239
RTF2 replication termination factor 2 2.28657
H2BC4 H2B clustered histone 4 2.28305
TEX2 testis expressed 2 2.28054
TBXA2R thromboxane A2 receptor 2.27814
TUBA4A tubulin, alpha 4a 2.277
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 2.27665
UCN urocortin 2.27021
GSTP1 glutathione S-transferase pi 1 2.27018
SDK2 sidekick cell adhesion molecule 2 2.27011
H2AC25 H2A clustered histone 25 2.26907
CCDC25 coiled-coil domain containing 25 2.2655
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 2.26374
RNF13 ring finger protein 13 2.2632
DENND4C DENN/MADD domain containing 4C 2.26116
KCTD13 potassium channel tetramerization domain containing 13 2.25826
OAT ornithine aminotransferase 2.25756
CLSTN3 calsyntenin 3 2.25658
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 2.25372
DYNC2I1 dynein 2 intermediate chain 1 2.24997
MARCHF2 membrane associated ring-CH-type finger 2 2.2491
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 2.24909
CCL3L3 chemokine (C-C motif) ligand 3-like 3 2.24536
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 2.24452
PICK1 protein interacting with PRKCA 1 2.2422
KLF7 Kruppel-like factor 7 (ubiquitous) 2.24152
CLDN6 claudin 6 2.23993
SBDS Shwachman-Bodian-Diamond syndrome 2.23975
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 2.23964
LACTB2 lactamase, beta 2 2.23789
TSHZ2 teashirt zinc finger homeobox 2 2.23633
IL17RA interleukin 17 receptor A 2.23622
MLF2 myeloid leukemia factor 2 2.23457
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 2.23382
KIAA1614 KIAA1614 2.23195
PEPD peptidase D 2.22697
ZMIZ1 zinc finger, MIZ-type containing 1 2.22641
KLHDC3 kelch domain containing 3 2.22511
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 2.2245
PEX3 peroxisomal biogenesis factor 3 2.22437
MON1B MON1 secretory trafficking family member B 2.22356
MTMR14 myotubularin related protein 14 2.2229
DHDDS dehydrodolichyl diphosphate synthase 2.2185
ZNF34 zinc finger protein 34 2.21658
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.21494
KATNB1 katanin p80 (WD repeat containing) subunit B 1 2.21425
UEVLD UEV and lactate/malate dehyrogenase domains 2.21326
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 2.21015
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 2.20964
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 2.20903
PHF1 PHD finger protein 1 2.20854
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 2.20304
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 2.20161
GOLGA7 golgin A7 2.20105
SIRT4 sirtuin 4 2.20052
IGHMBP2 immunoglobulin mu binding protein 2 2.19907
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) 2.19618
KATNIP katanin interacting protein 2.19586
NPDC1 neural proliferation, differentiation and control, 1 2.19407
PIGH phosphatidylinositol glycan anchor biosynthesis, class H 2.19399
SPI1 Spi-1 proto-oncogene 2.19134
ACOT13 acyl-CoA thioesterase 13 2.19087
TAOK2 TAO kinase 2 2.1903
FGD6 FYVE, RhoGEF and PH domain containing 6 2.1882
CRK v-crk avian sarcoma virus CT10 oncogene homolog 2.18787
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 2.18677
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 2.18673
DOC2A double C2-like domains, alpha 2.18322
INSM1 insulinoma-associated 1 2.18077
FAM131A family with sequence similarity 131, member A 2.17987
WIPI2 WD repeat domain, phosphoinositide interacting 2 2.17664
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 2.17474
CTBP2 C-terminal binding protein 2 2.17219
BBS4 Bardet-Biedl syndrome 4 2.16987
TOP6BL TOP6B like initiator of meiotic double strand breaks 2.16856
RABAC1 Rab acceptor 1 (prenylated) 2.1683
DUX4 double homeobox 4 2.16824
FIG4 FIG4 phosphoinositide 5-phosphatase 2.16549
OCEL1 occludin/ELL domain containing 1 2.16425
WFDC2 WAP four-disulfide core domain 2 2.1635
LDOC1 leucine zipper, down-regulated in cancer 1 2.16081
IFT57 intraflagellar transport 57 2.15722
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 2.1562
ACE angiotensin I converting enzyme 2.15476
MED20 mediator complex subunit 20 2.15276
TRAPPC14 trafficking protein particle complex subunit 14 2.1488
UBE2W ubiquitin-conjugating enzyme E2W (putative) 2.1485
LZTS3 leucine zipper, putative tumor suppressor family member 3 2.14726
NGF nerve growth factor (beta polypeptide) 2.14529
CRIP2 cysteine-rich protein 2 2.14517
GRAPL GRB2-related adaptor protein-like 2.14428
RASL12 RAS-like, family 12 2.14119
GBA1 glucosylceramidase beta 1 2.14047
LIAS lipoic acid synthetase 2.13763
CMTR1 cap methyltransferase 1 2.13699
SGMS1 sphingomyelin synthase 1 2.13579
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 2.13285
IGF1R insulin-like growth factor 1 receptor 2.13202
MALT1 MALT1 paracaspase 2.12857
COL1A1 collagen, type I, alpha 1 2.12414
TYW2 tRNA wybutosine-synthesizing protein 2 2.1214
A4GALT alpha 1,4-galactosyltransferase 2.12077
RUSF1 RUS family member 1 2.11577
GRWD1 glutamate-rich WD repeat containing 1 2.11527
SLC38A12 solute carrier family 38 member 12 2.11465
FUCA1 fucosidase, alpha-L- 1, tissue 2.1132
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 2.10764
PXMP4 peroxisomal membrane protein 4, 24kDa 2.10646
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 2.10348
ZNF184 zinc finger protein 184 2.10192
SSBP2 single-stranded DNA binding protein 2 2.10012
RGN regucalcin 2.09855
PARG poly (ADP-ribose) glycohydrolase 2.09805
MICU1 mitochondrial calcium uptake 1 2.0979
RNF40 ring finger protein 40, E3 ubiquitin protein ligase 2.09587
MORN1 MORN repeat containing 1 2.0952
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.0949
OGFR opioid growth factor receptor 2.09462
HPCAL1 hippocalcin-like 1 2.09229
NECAP2 NECAP endocytosis associated 2 2.09058
HEXIM1 hexamethylene bis-acetamide inducible 1 2.08768
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 2.0855
TCN2 transcobalamin II 2.08524
TPPP tubulin polymerization promoting protein 2.08503
NFS1 NFS1 cysteine desulfurase 2.08329
TEAD3 TEA domain family member 3 2.08276
TIAM1 T-cell lymphoma invasion and metastasis 1 2.08211
LBR lamin B receptor 2.07904
PCDH1 protocadherin 1 2.07742
EMX2 empty spiracles homeobox 2 2.07685
GET3 guided entry of tail-anchored proteins factor 3, ATPase 2.07495
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.07476
ADAM15 ADAM metallopeptidase domain 15 2.0737
KDM5A lysine (K)-specific demethylase 5A 2.07302
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.07227
SLC22A17 solute carrier family 22, member 17 2.07096
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 2.06916
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 2.0673
CCL14 chemokine (C-C motif) ligand 14 2.0647
RAB3A RAB3A, member RAS oncogene family 2.06241
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 2.06204
ACOT8 acyl-CoA thioesterase 8 2.06102
PTK2 protein tyrosine kinase 2 2.05762
KIAA0319 KIAA0319 2.05728
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 2.05581
CLBA1 clathrin binding box of aftiphilin containing 1 2.05383
GRK3 G protein-coupled receptor kinase 3 2.05258
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like 2.0512
BCCIP BRCA2 and CDKN1A interacting protein 2.04954
EPN2 epsin 2 2.04458
ING4 inhibitor of growth family, member 4 2.0443
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 2.04383
DPH2 DPH2 homolog (S. cerevisiae) 2.03988
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 2.03942
SLC12A9 solute carrier family 12, member 9 2.03881
RAB6B RAB6B, member RAS oncogene family 2.03494
JPH2 junctophilin 2 2.02977
OSBPL1A oxysterol binding protein-like 1A 2.02931
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 2.0293
TLN1 talin 1 2.02835
ING1 inhibitor of growth family, member 1 2.02676
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 2.02228
GAL3ST4 galactose-3-O-sulfotransferase 4 2.02185
GPN3 GPN-loop GTPase 3 2.02117
SRP54 signal recognition particle 54kDa 2.01921
TSPAN12 tetraspanin 12 2.0184
ZNF322 zinc finger protein 322 2.01768
SH3BP1 SH3-domain binding protein 1 2.01248
UNC45A unc-45 homolog A (C. elegans) 2.01202
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.01162
TMEM59L transmembrane protein 59-like 2.01146
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.01065
PALM paralemmin 2.01061
TMSB10 thymosin beta 10 2.01052
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 2.00923
NCOA3 nuclear receptor coactivator 3 2.00823
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 2.00736
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 2.00614
GRIA2 glutamate receptor, ionotropic, AMPA 2 2.00511
ACTR3B ARP3 actin-related protein 3 homolog B (yeast) 2.00406
ZNG1A Zn regulated GTPase metalloprotein activator 1A 2.00299
CARD10 caspase recruitment domain family, member 10 2.0028
RGPD1 RANBP2-like and GRIP domain containing 1 2.00183
CELF3 CUGBP, Elav-like family member 3 2.00032

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -9.78528
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -9.74963
PGM1 phosphoglucomutase 1 -9.5876
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -8.77947
TCERG1 transcription elongation regulator 1 -8.55747
FOSL1 FOS-like antigen 1 -8.45488
TLCD3A TLC domain containing 3A -8.31458
KEAP1 kelch-like ECH-associated protein 1 -8.27269
UBE2C ubiquitin-conjugating enzyme E2C -8.09367
HMGA2 high mobility group AT-hook 2 -7.85801
ETFB electron-transfer-flavoprotein, beta polypeptide -7.77182
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -7.63345
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -7.43128
RPIA ribose 5-phosphate isomerase A -7.10377
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -7.05453
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -6.90373
STAP2 signal transducing adaptor family member 2 -6.88824
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -6.64143
SLC35F2 solute carrier family 35, member F2 -6.63711
CCNA2 cyclin A2 -6.61455
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -6.51991
CDC20 cell division cycle 20 -6.43281
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -6.38428
TRIB3 tribbles pseudokinase 3 -6.09619
CCDC86 coiled-coil domain containing 86 -6.05225
DERA deoxyribose-phosphate aldolase (putative) -6.05088
LDHD lactate dehydrogenase D -5.82855
PLK1 polo-like kinase 1 -5.63296
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -5.54063
PCCB propionyl CoA carboxylase, beta polypeptide -5.50347
CD320 CD320 molecule -5.44806
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -5.36465
AURKB aurora kinase B -5.35118
TMEM109 transmembrane protein 109 -5.33919
CDK4 cyclin-dependent kinase 4 -5.27917
TMEM97 transmembrane protein 97 -5.24369
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -5.21532
LRRC41 leucine rich repeat containing 41 -5.11577
LOC124907782 dual specificity protein phosphatase 22 -5.10359
GLOD4 glyoxalase domain containing 4 -5.03879
ATF5 activating transcription factor 5 -4.94978
CRELD2 cysteine-rich with EGF-like domains 2 -4.93998
DCTD dCMP deaminase -4.90098
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.89339
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -4.87187
SPAG7 sperm associated antigen 7 -4.86308
MAPK13 mitogen-activated protein kinase 13 -4.78651
SOAT2 sterol O-acyltransferase 2 -4.73849
TATDN2 TatD DNase domain containing 2 -4.72783
CHEK1 checkpoint kinase 1 -4.69259
C5 complement component 5 -4.64284
ITGB5 integrin, beta 5 -4.63712
ECH1 enoyl CoA hydratase 1, peroxisomal -4.57846
MRPS16 mitochondrial ribosomal protein S16 -4.55686
B4GAT1 beta-1,4-glucuronyltransferase 1 -4.51893
NNT nicotinamide nucleotide transhydrogenase -4.50757
NUP85 nucleoporin 85kDa -4.45519
TCTN1 tectonic family member 1 -4.38601
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -4.3148
HEATR1 HEAT repeat containing 1 -4.28546
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -4.28156
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -4.24324
TNIP1 TNFAIP3 interacting protein 1 -4.20008
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -4.1787
GALE UDP-galactose-4-epimerase -4.15156
CASP7 caspase 7, apoptosis-related cysteine peptidase -4.11295
MRPL12 mitochondrial ribosomal protein L12 -4.08613
NT5DC2 5'-nucleotidase domain containing 2 -4.08168
FOXM1 forkhead box M1 -4.0494
DSG2 desmoglein 2 -4.02961
GTPBP8 GTP-binding protein 8 (putative) -3.90819
GTPBP6 GTP binding protein 6 (putative) -3.89395
ISOC1 isochorismatase domain containing 1 -3.88537
TPM1 tropomyosin 1 (alpha) -3.83487
CDK1 cyclin-dependent kinase 1 -3.82798
DCK deoxycytidine kinase -3.80989
ACOD1 aconitate decarboxylase 1 -3.7865
SENP6 SUMO1/sentrin specific peptidase 6 -3.76545
PHF2 PHD finger protein 2 -3.73671
KLHL21 kelch-like family member 21 -3.71942
MELK maternal embryonic leucine zipper kinase -3.71671
SQOR sulfide quinone oxidoreductase -3.70127
SLC35B1 solute carrier family 35, member B1 -3.69209
TTC19 tetratricopeptide repeat domain 19 -3.6825
RAP1GAP RAP1 GTPase activating protein -3.66276
CRYZ crystallin, zeta (quinone reductase) -3.65924
FGFR4 fibroblast growth factor receptor 4 -3.64321
MICALL1 MICAL-like 1 -3.62601
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -3.62217
ZBED1 zinc finger, BED-type containing 1 -3.57641
PROS1 protein S (alpha) -3.54635
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -3.53905
SPDEF SAM pointed domain containing ETS transcription factor -3.52983
ENOPH1 enolase-phosphatase 1 -3.47658
FHL2 four and a half LIM domains 2 -3.45682
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.42026
CCNB2 cyclin B2 -3.40349
EXOSC8 exosome component 8 -3.40279
TIMCC TIM double twin CX3C motif chaperone -3.36526
PROSER1 proline and serine rich 1 -3.35432
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -3.29969
MYO19 myosin XIX -3.28654
ICAM3 intercellular adhesion molecule 3 -3.27527
TEAD4 TEA domain family member 4 -3.26929
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -3.20492
FAIM Fas apoptotic inhibitory molecule -3.20169
NOP14 NOP14 nucleolar protein -3.18291
PPIC peptidylprolyl isomerase C (cyclophilin C) -3.15405
POLE polymerase (DNA directed), epsilon, catalytic subunit -3.13971
CCNB1 cyclin B1 -3.13365
HJURP Holliday junction recognition protein -3.12278
VDAC1 voltage-dependent anion channel 1 -3.12122
REEP5 receptor accessory protein 5 -3.11162
NISCH nischarin -3.09378
LYRM1 LYR motif containing 1 -3.09033
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase -3.09012
CCDC59 coiled-coil domain containing 59 -3.07679
MRPS2 mitochondrial ribosomal protein S2 -3.07366
PPARG peroxisome proliferator-activated receptor gamma -3.06423
ANXA7 annexin A7 -3.06423
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.06137
IPO5 importin 5 -3.05794
GNPDA1 glucosamine-6-phosphate deaminase 1 -3.051
NUP54 nucleoporin 54kDa -3.04851
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -2.99124
KIF4A kinesin family member 4A -2.96899
TM9SF3 transmembrane 9 superfamily member 3 -2.9654
RXYLT1 ribitol xylosyltransferase 1 -2.96409
IDE insulin-degrading enzyme -2.9563
SYPL1 synaptophysin-like 1 -2.95155
HADH hydroxyacyl-CoA dehydrogenase -2.93878
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) -2.92442
TSPAN4 tetraspanin 4 -2.89771
ASGR2 asialoglycoprotein receptor 2 -2.89281
ZNF586 zinc finger protein 586 -2.89085
NUP88 nucleoporin 88kDa -2.88763
CNPY3 canopy FGF signaling regulator 3 -2.87942
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -2.8782
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.87568
PUF60 poly-U binding splicing factor 60KDa -2.87041
DEPDC1 DEP domain containing 1 -2.85736
ATXN10 ataxin 10 -2.84943
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.8492
FBXO7 F-box protein 7 -2.8421
OIP5 Opa interacting protein 5 -2.8373
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase -2.81763
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.81094
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.80063
FXN frataxin -2.7997
PTPN7 protein tyrosine phosphatase, non-receptor type 7 -2.7955
SPAG4 sperm associated antigen 4 -2.78749
OXCT1 3-oxoacid CoA transferase 1 -2.78698
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.7852
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -2.77299
USP22 ubiquitin specific peptidase 22 -2.77087
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -2.77021
ZMYND11 zinc finger, MYND-type containing 11 -2.76121
SUMO4 small ubiquitin-like modifier 4 -2.75754
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.74742
SOX4 SRY (sex determining region Y)-box 4 -2.74372
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -2.74294
TSPAN6 tetraspanin 6 -2.74244
MCM5 minichromosome maintenance complex component 5 -2.73228
AVEN apoptosis, caspase activation inhibitor -2.72662
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.71957
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.71851
RCN1 reticulocalbin 1, EF-hand calcium binding domain -2.71272
TFDP1 transcription factor Dp-1 -2.71188
PSAT1 phosphoserine aminotransferase 1 -2.70027
KIF11 kinesin family member 11 -2.69764
CD99 CD99 molecule -2.69346
CDCA8 cell division cycle associated 8 -2.68786
SCCPDH saccharopine dehydrogenase (putative) -2.67416
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.67338
F5 coagulation factor V (proaccelerin, labile factor) -2.67239
GAS2 growth arrest-specific 2 -2.66593
APOA2 apolipoprotein A-II -2.66259
GPN1 GPN-loop GTPase 1 -2.66069
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.65626
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -2.64882
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.64835
LMNB1 lamin B1 -2.64746
GAR1 GAR1 ribonucleoprotein -2.63907
QTRT1 queuine tRNA-ribosyltransferase 1 -2.63746
NCAPH non-SMC condensin I complex, subunit H -2.63076
ASF1B anti-silencing function 1B histone chaperone -2.62862
MATN3 matrilin 3 -2.61612
FXYD3 FXYD domain containing ion transport regulator 3 -2.61194
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -2.60436
FOXE1 forkhead box E1 -2.59782
TFF2 trefoil factor 2 -2.59553
AMBP alpha-1-microglobulin/bikunin precursor -2.58169
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -2.57179
MRPL19 mitochondrial ribosomal protein L19 -2.5713
SNRPA small nuclear ribonucleoprotein polypeptide A -2.56954
TOR1A torsin family 1, member A (torsin A) -2.56734
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa -2.56459
CHPT1 choline phosphotransferase 1 -2.55518
VAMP5 vesicle-associated membrane protein 5 -2.55307
TIMELESS timeless circadian clock -2.55132
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.54471
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.53994
PTPN9 protein tyrosine phosphatase, non-receptor type 9 -2.53307
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like -2.5284
ORM2 orosomucoid 2 -2.52022
GTSE1 G-2 and S-phase expressed 1 -2.51694
MAPK12 mitogen-activated protein kinase 12 -2.50965
KIF14 kinesin family member 14 -2.49846
HRAS Harvey rat sarcoma viral oncogene homolog -2.49651
CASC3 cancer susceptibility candidate 3 -2.49052
DKK1 dickkopf WNT signaling pathway inhibitor 1 -2.48844
RBFA ribosome binding factor A (putative) -2.48021
CDT1 chromatin licensing and DNA replication factor 1 -2.47914
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 -2.4708
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.46649
GPR15 G protein-coupled receptor 15 -2.46475
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -2.45719
ERBB3 erb-b2 receptor tyrosine kinase 3 -2.45502
PON2 paraoxonase 2 -2.44942
ADSS2 adenylosuccinate synthase 2 -2.44198
SPRY2 sprouty homolog 2 (Drosophila) -2.44092
ACTR10 actin-related protein 10 homolog (S. cerevisiae) -2.43596
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 -2.43523
ACOT2 acyl-CoA thioesterase 2 -2.43302
TPX2 TPX2, microtubule-associated -2.43293
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.43127
FBN1 fibrillin 1 -2.42587
NENF neudesin neurotrophic factor -2.41662
BIRC5 baculoviral IAP repeat containing 5 -2.4164
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 -2.40742
CDC25A cell division cycle 25A -2.39621
NCK2 NCK adaptor protein 2 -2.38397
TRIP13 thyroid hormone receptor interactor 13 -2.37313
PFKL phosphofructokinase, liver -2.36689
CRTAP cartilage associated protein -2.3643
CTDNEP1 CTD nuclear envelope phosphatase 1 -2.35981
TICAM1 toll-like receptor adaptor molecule 1 -2.35833
VAV3 vav 3 guanine nucleotide exchange factor -2.34864
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -2.34807
AGMAT agmatine ureohydrolase (agmatinase) -2.34252
RXRG retinoid X receptor, gamma -2.33715
ANAPC1 anaphase promoting complex subunit 1 -2.33687
HOXB7 homeobox B7 -2.33661
EPS8L3 EPS8-like 3 -2.33611
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase -2.33543
CDC73 cell division cycle 73 -2.33324
ANK1 ankyrin 1, erythrocytic -2.32574
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.32336
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -2.31651
NLE1 notchless homolog 1 (Drosophila) -2.31222
SEC23A Sec23 homolog A (S. cerevisiae) -2.31213
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -2.30703
HLA-DOB major histocompatibility complex, class II, DO beta -2.30135
FST follistatin -2.29469
LHX3 LIM homeobox 3 -2.29418
MKI67 marker of proliferation Ki-67 -2.28992
PLEKHA6 pleckstrin homology domain containing, family A member 6 -2.2891
AHSG alpha-2-HS-glycoprotein -2.28408
CHAF1A chromatin assembly factor 1, subunit A (p150) -2.27049
SPATA20 spermatogenesis associated 20 -2.27003
GBE1 glucan (1,4-alpha-), branching enzyme 1 -2.26524
PYCR1 pyrroline-5-carboxylate reductase 1 -2.26514
CASD1 CAS1 domain containing 1 -2.26374
IFRD2 interferon-related developmental regulator 2 -2.26346
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.2628
SCUBE2 signal peptide, CUB domain, EGF-like 2 -2.25925
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -2.25907
RPL3L ribosomal protein L3-like -2.25814
KRCC1 lysine-rich coiled-coil 1 -2.25372
MRPL35 mitochondrial ribosomal protein L35 -2.25194
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -2.2491
CHD1 chromodomain helicase DNA binding protein 1 -2.24712
BACE1 beta-site APP-cleaving enzyme 1 -2.24591
CKM creatine kinase, muscle -2.2443
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -2.24416
ZBTB35 zinc finger and BTB domain containing 35 -2.24212
DBF4 DBF4 zinc finger -2.23492
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.22853
ERMAP erythroblast membrane-associated protein (Scianna blood group) -2.2275
PITX2 paired-like homeodomain 2 -2.22334
HMGN3 high mobility group nucleosomal binding domain 3 -2.22153
MYL5 myosin, light chain 5, regulatory -2.22113
PTX3 pentraxin 3, long -2.21501
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta -2.21429
RPH3AL rabphilin 3A-like (without C2 domains) -2.20983
UBE2E1 ubiquitin-conjugating enzyme E2E 1 -2.20309
PAX1 paired box 1 -2.20283
RCC1L RCC1 like -2.20263
ILKAP integrin-linked kinase-associated serine/threonine phosphatase -2.19777
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.19607
COPS3 COP9 signalosome subunit 3 -2.19512
SRD5A3 steroid 5 alpha-reductase 3 -2.19418
PPP1R8 protein phosphatase 1, regulatory subunit 8 -2.18628
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 -2.18578
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 -2.18235
ENOSF1 enolase superfamily member 1 -2.1803
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.17766
RNF144A ring finger protein 144A -2.17119
ECPAS Ecm29 proteasome adaptor and scaffold -2.16735
C1QBP complement component 1, q subcomponent binding protein -2.16549
STEAP3 STEAP family member 3, metalloreductase -2.16515
TRAF1 TNF receptor-associated factor 1 -2.16312
TERT telomerase reverse transcriptase -2.16133
PPIE peptidylprolyl isomerase E (cyclophilin E) -2.16063
LTBP1 latent transforming growth factor beta binding protein 1 -2.15964
SCMH1 sex comb on midleg homolog 1 (Drosophila) -2.15862
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 -2.15791
ELOVL1 ELOVL fatty acid elongase 1 -2.15771
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 -2.15764
PCNT pericentrin -2.15212
COCH cochlin -2.15188
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.14944
MYO5C myosin VC -2.1479
NLRX1 NLR family member X1 -2.14136
ANXA6 annexin A6 -2.14095
WTAP Wilms tumor 1 associated protein -2.14032
ADORA2B adenosine A2b receptor -2.13942
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.13898
MAGEL2 melanoma antigen family L2 -2.13601
APOH apolipoprotein H (beta-2-glycoprotein I) -2.13414
PGLYRP4 peptidoglycan recognition protein 4 -2.12892
ELAC2 elaC ribonuclease Z 2 -2.1288
BRCA1 breast cancer 1, early onset -2.12647
SSH1 slingshot protein phosphatase 1 -2.12642
LRRC40 leucine rich repeat containing 40 -2.12455
AP4M1 adaptor-related protein complex 4, mu 1 subunit -2.12134
EDA2R ectodysplasin A2 receptor -2.12106
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.11893
PIEZO1 piezo-type mechanosensitive ion channel component 1 -2.11332
ENDOG endonuclease G -2.11165
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -2.10855
LMF2 lipase maturation factor 2 -2.10422
APOB apolipoprotein B -2.10225
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) -2.09969
CENPN centromere protein N -2.09926
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 -2.09827
PARVB parvin, beta -2.09735
MDN1 MDN1, midasin homolog (yeast) -2.09046
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -2.08984
MRPS7 mitochondrial ribosomal protein S7 -2.08972
HMMR hyaluronan-mediated motility receptor (RHAMM) -2.08788
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -2.08455
COA3 cytochrome c oxidase assembly factor 3 -2.08312
MRM3 mitochondrial rRNA methyltransferase 3 -2.08267
THOC1 THO complex 1 -2.08225
KRT13 keratin 13, type I -2.08068
TF transferrin -2.07978
ATP9B ATPase, class II, type 9B -2.07876
LRP12 low density lipoprotein receptor-related protein 12 -2.07725
ARL14 ADP-ribosylation factor-like 14 -2.07556
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 -2.07422
NSD2 nuclear receptor binding SET domain protein 2 -2.07326
LAD1 ladinin 1 -2.07088
RFC3 replication factor C (activator 1) 3, 38kDa -2.06278
LRRC47 leucine rich repeat containing 47 -2.05932
APIP APAF1 interacting protein -2.05621
GH1 growth hormone 1 -2.05359
NID2 nidogen 2 (osteonidogen) -2.04988
RWDD3 RWD domain containing 3 -2.04883
MRPS27 mitochondrial ribosomal protein S27 -2.0486
EI24 etoposide induced 2.4 -2.04748
POLR1G RNA polymerase I subunit G -2.04563
REV1 REV1, polymerase (DNA directed) -2.04547
APOE apolipoprotein E -2.0454
LOC100652777 group 10 secretory phospholipase A2-like -2.04304
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -2.04198
AFG3L2 AFG3-like AAA ATPase 2 -2.03606
PRDX4 peroxiredoxin 4 -2.03477
EXOSC9 exosome component 9 -2.03462
FAM193A family with sequence similarity 193, member A -2.03382
CCR8 chemokine (C-C motif) receptor 8 -2.03201
CXCL8 chemokine (C-X-C motif) ligand 8 -2.02639
PLK4 polo-like kinase 4 -2.02625
APOBEC3A_B APOBEC3A and APOBEC3B deletion hybrid -2.02311
PRC1 protein regulator of cytokinesis 1 -2.02161
MYL1 myosin, light chain 1, alkali; skeletal, fast -2.0213
FBF1 Fas (TNFRSF6) binding factor 1 -2.02108
PRAF2 PRA1 domain family, member 2 -2.01996
VRK2 vaccinia related kinase 2 -2.01937
FANCI Fanconi anemia, complementation group I -2.0183
HDDC2 HD domain containing 2 -2.01793
TTR transthyretin -2.01562
LAGE3 L antigen family, member 3 -2.0151
CLEC11A C-type lectin domain family 11, member A -2.01497
THOC7 THO complex 7 -2.0146
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -2.01322
CEP170 centrosomal protein 170kDa -2.01113
LAP3 leucine aminopeptidase 3 -2.00902
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) -2.00296
PYGL phosphorylase, glycogen, liver -2.00198
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.00122