CRCGN013_HEPG2_24H:K11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vorinostat 1.25 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

586 genes differentially expressed following the CRCGN013_HEPG2_24H:K11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FOXO4 forkhead box O4 10.0
UBE2L6 ubiquitin-conjugating enzyme E2L 6 9.81589
CDPF1 cysteine-rich, DPF motif domain containing 1 9.72286
CBR1 carbonyl reductase 1 8.88272
DNM1 dynamin 1 8.7196
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 7.81199
ALDOC aldolase C, fructose-bisphosphate 6.40924
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 6.04329
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 5.70862
MYC v-myc avian myelocytomatosis viral oncogene homolog 5.67796
NPDC1 neural proliferation, differentiation and control, 1 5.55088
H2BC12 H2B clustered histone 12 5.44695
HMG20B high mobility group 20B 5.3931
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 5.36987
LSR lipolysis stimulated lipoprotein receptor 5.35122
TCEA2 transcription elongation factor A (SII), 2 5.24228
MVP major vault protein 5.2148
PLA2G15 phospholipase A2, group XV 5.11718
TAC4 tachykinin 4 (hemokinin) 5.09431
SKIC2 SKI2 subunit of superkiller complex 5.03347
CGRRF1 cell growth regulator with ring finger domain 1 4.90787
PLS1 plastin 1 4.82989
TMEM50A transmembrane protein 50A 4.47838
LRP10 low density lipoprotein receptor-related protein 10 4.39632
ABHD4 abhydrolase domain containing 4 4.39014
ANO10 anoctamin 10 4.35329
DUSP6 dual specificity phosphatase 6 4.27816
BPHL biphenyl hydrolase-like (serine hydrolase) 4.21388
ARFIP2 ADP-ribosylation factor interacting protein 2 4.08299
HMOX1 heme oxygenase 1 4.06218
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 3.95523
STX1A syntaxin 1A (brain) 3.92609
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.88831
EGR1 early growth response 1 3.87637
AMDHD2 amidohydrolase domain containing 2 3.86806
CNPY4 canopy FGF signaling regulator 4 3.85588
INTS3 integrator complex subunit 3 3.79868
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 3.78251
CXCL2 chemokine (C-X-C motif) ligand 2 3.75473
GPR162 G protein-coupled receptor 162 3.71844
RSU1 Ras suppressor protein 1 3.71096
LGMN legumain 3.70347
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 3.6532
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.65013
ZDHHC6 zinc finger, DHHC-type containing 6 3.64158
MNAT1 MNAT CDK-activating kinase assembly factor 1 3.6373
DPH2 DPH2 homolog (S. cerevisiae) 3.60043
STXBP1 syntaxin binding protein 1 3.58495
ABHD6 abhydrolase domain containing 6 3.58414
CHMP6 charged multivesicular body protein 6 3.5539
PTPN12 protein tyrosine phosphatase, non-receptor type 12 3.54464
ZNF646 zinc finger protein 646 3.47626
TCF15 transcription factor 15 (basic helix-loop-helix) 3.4639
IER3 immediate early response 3 3.42495
TLE6 transducin-like enhancer of split 6 3.40128
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 3.39679
ELAVL3 ELAV like neuron-specific RNA binding protein 3 3.38818
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 3.38208
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 3.378
TWF2 twinfilin actin binding protein 2 3.31163
PRKCD protein kinase C, delta 3.30903
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.22438
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 3.21375
E2F2 E2F transcription factor 2 3.19602
GPR137B G protein-coupled receptor 137B 3.19349
BORCS6 BLOC-1 related complex subunit 6 3.15466
TIMP2 TIMP metallopeptidase inhibitor 2 3.08888
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 3.07456
USP6NL USP6 N-terminal like 3.06041
CBR3 carbonyl reductase 3 3.05685
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 3.0469
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.04104
PRCP prolylcarboxypeptidase (angiotensinase C) 3.0328
IGFALS insulin-like growth factor binding protein, acid labile subunit 3.02167
SDK2 sidekick cell adhesion molecule 2 2.97987
DDN dendrin 2.96597
CARMIL1 capping protein regulator and myosin 1 linker 1 2.9579
FABP2 fatty acid binding protein 2, intestinal 2.94605
PTMS parathymosin 2.94059
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 2.93939
GDE1 glycerophosphodiester phosphodiesterase 1 2.92999
TRAPPC6A trafficking protein particle complex 6A 2.91161
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.90089
CABP1 calcium binding protein 1 2.89507
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 2.87284
ROM1 retinal outer segment membrane protein 1 2.87233
PECR peroxisomal trans-2-enoyl-CoA reductase 2.86211
ADGRD2 adhesion G protein-coupled receptor D2 2.852
BAMBI BMP and activin membrane-bound inhibitor 2.84956
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 2.8493
GSTZ1 glutathione S-transferase zeta 1 2.84075
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 2.82948
BBC3 BCL2 binding component 3 2.81981
FOXC1 forkhead box C1 2.81272
CCDC71 coiled-coil domain containing 71 2.80931
CLSTN3 calsyntenin 3 2.80536
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.79954
SETD1A SET domain containing 1A 2.78866
AARS1 alanyl-tRNA synthetase 1 2.78183
TXNRD1 thioredoxin reductase 1 2.7764
SCYL3 SCY1-like 3 (S. cerevisiae) 2.77261
RTN2 reticulon 2 2.77255
FAM110A family with sequence similarity 110, member A 2.76885
SIX1 SIX homeobox 1 2.74782
GRWD1 glutamate-rich WD repeat containing 1 2.74153
UBQLN2 ubiquilin 2 2.74075
BMP4 bone morphogenetic protein 4 2.73938
FSTL1 follistatin-like 1 2.73408
LCN2 lipocalin 2 2.73318
CALM3 calmodulin 3 (phosphorylase kinase, delta) 2.73008
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 2.72956
CATSPERH catsper channel auxiliary subunit eta 2.72601
PDLIM1 PDZ and LIM domain 1 2.72191
PPP4C protein phosphatase 4, catalytic subunit 2.71948
MAPK3 mitogen-activated protein kinase 3 2.71243
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.70276
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 2.69468
DOC2A double C2-like domains, alpha 2.68176
CTSL cathepsin L 2.67861
FZD7 frizzled class receptor 7 2.67455
ZNG1A Zn regulated GTPase metalloprotein activator 1A 2.66011
SCGB1D1 secretoglobin, family 1D, member 1 2.65906
MDFI MyoD family inhibitor 2.65714
KCTD17 potassium channel tetramerization domain containing 17 2.65611
KLK1 kallikrein 1 2.63165
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 2.62149
BCKDK branched chain ketoacid dehydrogenase kinase 2.59845
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 2.59681
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 2.5901
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.581
GIPR gastric inhibitory polypeptide receptor 2.57658
UNC93B1 unc-93 homolog B1 (C. elegans) 2.57227
HOXB3 homeobox B3 2.57001
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.56905
CYB561 cytochrome b561 2.56363
SEPHS2 selenophosphate synthetase 2 2.56206
ZCCHC14 zinc finger, CCHC domain containing 14 2.54706
CPLX3 complexin 3 2.5464
MYOG myogenin (myogenic factor 4) 2.54481
CCND3 cyclin D3 2.5433
LOC127933115 uncharacterized LOC127933115 2.54155
INTS5 integrator complex subunit 5 2.53666
SETD3 SET domain containing 3 2.53505
TMEM59L transmembrane protein 59-like 2.53113
OSGIN1 oxidative stress induced growth inhibitor 1 2.52164
CALU calumenin 2.52116
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.50168
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 2.49769
MOCS3 molybdenum cofactor synthesis 3 2.49084
EFNB1 ephrin-B1 2.48594
INPP1 inositol polyphosphate-1-phosphatase 2.47653
EPN2 epsin 2 2.46954
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.46818
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 2.46656
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.46352
UGDH UDP-glucose 6-dehydrogenase 2.45559
CYTH1 cytohesin 1 2.45362
FAT1 FAT atypical cadherin 1 2.45358
DUX4 double homeobox 4 2.45023
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.44869
PTP4A3 protein tyrosine phosphatase type IVA, member 3 2.44527
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 2.44218
IGF1R insulin-like growth factor 1 receptor 2.44184
CLDN6 claudin 6 2.44
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.43763
CLEC16A C-type lectin domain family 16, member A 2.42438
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 2.42159
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 2.42121
GRN granulin 2.39345
ACBD4 acyl-CoA binding domain containing 4 2.39038
HPCA hippocalcin 2.38024
PLK2 polo-like kinase 2 2.37728
CELF3 CUGBP, Elav-like family member 3 2.37643
TMEM121 transmembrane protein 121 2.37612
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 2.37453
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 2.37033
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 2.36929
KIF5C kinesin family member 5C 2.36814
SHARPIN SHANK-associated RH domain interactor 2.36595
KHDC4 KH domain containing 4, pre-mRNA splicing factor 2.3649
DOK4 docking protein 4 2.35507
NEU2 sialidase 2 (cytosolic sialidase) 2.35384
WWC1 WW and C2 domain containing 1 2.35159
DDB2 damage-specific DNA binding protein 2, 48kDa 2.35084
C15ORF38-AP3S2 C15orf38-AP3S2 readthrough 2.34631
CYTH3 cytohesin 3 2.34266
RCE1 Ras converting CAAX endopeptidase 1 2.33818
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma 2.33404
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 2.33046
MOSPD3 motile sperm domain containing 3 2.32752
BIN3 bridging integrator 3 2.31282
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.31233
CRABP2 cellular retinoic acid binding protein 2 2.30196
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 2.3008
RUSF1 RUS family member 1 2.29897
NME7 NME/NM23 family member 7 2.29601
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 2.28996
ADAM10 ADAM metallopeptidase domain 10 2.28489
DENND2D DENN/MADD domain containing 2D 2.28252
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 2.28199
FAM110D family with sequence similarity 110, member D 2.27547
CCNJL cyclin J-like 2.27458
FKBP6 FK506 binding protein 6, 36kDa 2.27393
NPR1 natriuretic peptide receptor 1 2.27243
BCL2L1 BCL2-like 1 2.27173
ERI3 ERI1 exoribonuclease family member 3 2.26869
BCL2L10 BCL2-like 10 (apoptosis facilitator) 2.26599
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) 2.26355
NOSIP nitric oxide synthase interacting protein 2.26313
RB1CC1 RB1-inducible coiled-coil 1 2.26238
UCN urocortin 2.26105
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 2.25687
IQCC IQ motif containing C 2.25336
APEH acylaminoacyl-peptide hydrolase 2.25323
HABP4 hyaluronan binding protein 4 2.25062
SSTR3 somatostatin receptor 3 2.24763
LY6H lymphocyte antigen 6 complex, locus H 2.24401
METTL25B methyltransferase like 25B 2.23742
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.23683
SH3BP1 SH3-domain binding protein 1 2.23502
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 2.22867
SMAD3 SMAD family member 3 2.22659
FXYD7 FXYD domain containing ion transport regulator 7 2.22599
DPF1 D4, zinc and double PHD fingers family 1 2.22215
NIT1 nitrilase 1 2.21907
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.21354
OPRD1 opioid receptor, delta 1 2.21335
PLPP6 phospholipid phosphatase 6 2.20577
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa 2.20479
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.20373
RGN regucalcin 2.20234
HIC1 hypermethylated in cancer 1 2.19911
TMEM115 transmembrane protein 115 2.19351
GNS glucosamine (N-acetyl)-6-sulfatase 2.18562
RAB3A RAB3A, member RAS oncogene family 2.18364
NUCB2 nucleobindin 2 2.18345
GLRX glutaredoxin (thioltransferase) 2.18344
TLK2 tousled-like kinase 2 2.17405
ZBTB22 zinc finger and BTB domain containing 22 2.16943
CDK20 cyclin-dependent kinase 20 2.16714
PGPEP1 pyroglutamyl-peptidase I 2.16484
NCOA3 nuclear receptor coactivator 3 2.16271
COL1A1 collagen, type I, alpha 1 2.15423
DKKL1 dickkopf-like 1 2.15339
TMCO1 transmembrane and coiled-coil domains 1 2.15164
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 2.14989
IL18BP interleukin 18 binding protein 2.14849
MPV17L-BMERB1 MPV17L-BMERB1 readthrough 2.14774
PPARD peroxisome proliferator-activated receptor delta 2.14289
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 2.1425
ARHGAP12 Rho GTPase activating protein 12 2.14039
SPATS2 spermatogenesis associated, serine-rich 2 2.13774
KIAA1614 KIAA1614 2.12954
SYNGR3 synaptogyrin 3 2.12834
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 2.12641
KLHDC3 kelch domain containing 3 2.12578
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 2.12097
CLDN5 claudin 5 2.12017
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.12
ARL3 ADP-ribosylation factor-like 3 2.11819
CHN1 chimerin 1 2.11664
ZMAT3 zinc finger, matrin-type 3 2.11627
RNF170 ring finger protein 170 2.11617
FKBP8 FK506 binding protein 8, 38kDa 2.11444
TBX4 T-box 4 2.10916
H2BC5 H2B clustered histone 5 2.09992
TMEM132A transmembrane protein 132A 2.09713
SGCE sarcoglycan, epsilon 2.09458
SCARA3 scavenger receptor class A, member 3 2.09451
CTSB cathepsin B 2.09138
FCHO1 FCH domain only 1 2.091
TM7SF2 transmembrane 7 superfamily member 2 2.09053
TARBP1 TAR (HIV-1) RNA binding protein 1 2.08815
BEST1 bestrophin 1 2.08586
DOHH deoxyhypusine hydroxylase/monooxygenase 2.07944
TRIB1 tribbles pseudokinase 1 2.07922
SNPH syntaphilin 2.07774
FBXL18 F-box and leucine-rich repeat protein 18 2.07558
GPR45 G protein-coupled receptor 45 2.07407
KLK14 kallikrein-related peptidase 14 2.07402
HOXA4 homeobox A4 2.07335
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.07306
PDLIM7 PDZ and LIM domain 7 (enigma) 2.06954
ADRA2C adrenoceptor alpha 2C 2.06921
AMN amnion associated transmembrane protein 2.06712
HPSE heparanase 2.0668
CRIP2 cysteine-rich protein 2 2.06456
SNIP1 Smad nuclear interacting protein 1 2.06207
SYT1 synaptotagmin I 2.06157
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 2.06051
UBE3C ubiquitin protein ligase E3C 2.0605
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 2.05892
MXI1 MAX interactor 1, dimerization protein 2.05871
CCDC92 coiled-coil domain containing 92 2.05027
LDHC lactate dehydrogenase C 2.04743
FRMD4B FERM domain containing 4B 2.04493
DYNLT3 dynein, light chain, Tctex-type 3 2.04205
EGR3 early growth response 3 2.03906
TPPP tubulin polymerization promoting protein 2.03889
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 2.03706
MYLIP myosin regulatory light chain interacting protein 2.03606
CLPTM1 cleft lip and palate associated transmembrane protein 1 2.03517
CSNK1E casein kinase 1, epsilon 2.03401
GSTP1 glutathione S-transferase pi 1 2.02994
TERF2IP telomeric repeat binding factor 2, interacting protein 2.0299
MMP2 matrix metallopeptidase 2 2.02932
SYT12 synaptotagmin XII 2.02762
CCNG2 cyclin G2 2.0264
NGFR nerve growth factor receptor 2.02404
SSTR2 somatostatin receptor 2 2.02389
HSPA1A heat shock 70kDa protein 1A 2.0238
RBM12B RNA binding motif protein 12B 2.02229
PCDH1 protocadherin 1 2.02211
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 2.02043
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 2.01291
FBXO2 F-box protein 2 2.01251
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 2.00807
PRDM8 PR domain containing 8 2.00612
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 2.00309
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 2.00283
SLC12A9 solute carrier family 12, member 9 2.00049

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -8.35903
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -7.90691
TLCD3A TLC domain containing 3A -7.57142
UBE2C ubiquitin-conjugating enzyme E2C -7.18712
TMEM109 transmembrane protein 109 -6.34966
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -6.30727
STAP2 signal transducing adaptor family member 2 -6.23658
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -6.16687
FOSL1 FOS-like antigen 1 -5.9813
ICAM3 intercellular adhesion molecule 3 -5.90012
CD320 CD320 molecule -5.89859
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -5.88143
PGM1 phosphoglucomutase 1 -5.71222
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -5.54631
CCNA2 cyclin A2 -5.53042
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -5.48067
MRPS2 mitochondrial ribosomal protein S2 -5.38513
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -5.22428
ZW10 zw10 kinetochore protein -5.18419
ATF5 activating transcription factor 5 -4.84978
KEAP1 kelch-like ECH-associated protein 1 -4.8225
RRAGA Ras-related GTP binding A -4.80879
RPIA ribose 5-phosphate isomerase A -4.71602
CDK1 cyclin-dependent kinase 1 -4.71057
SOAT2 sterol O-acyltransferase 2 -4.66627
LRRC41 leucine rich repeat containing 41 -4.58033
TCERG1 transcription elongation regulator 1 -4.55017
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -4.53556
GTPBP8 GTP-binding protein 8 (putative) -4.46697
TCTN1 tectonic family member 1 -4.44846
TATDN2 TatD DNase domain containing 2 -4.44513
NUP85 nucleoporin 85kDa -4.35362
DCK deoxycytidine kinase -4.3235
CRELD2 cysteine-rich with EGF-like domains 2 -4.29108
DNM1L dynamin 1-like -4.2635
DERA deoxyribose-phosphate aldolase (putative) -4.24829
ZNF586 zinc finger protein 586 -4.22537
LOC124907782 dual specificity protein phosphatase 22 -4.21875
BDH1 3-hydroxybutyrate dehydrogenase, type 1 -4.2089
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -4.12665
TMEM97 transmembrane protein 97 -4.1018
WDR7 WD repeat domain 7 -4.09845
PLK1 polo-like kinase 1 -4.00317
CDK4 cyclin-dependent kinase 4 -3.99382
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.94179
CCNB1 cyclin B1 -3.94053
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -3.90821
CHEK1 checkpoint kinase 1 -3.83065
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -3.80702
C2CD5 C2 calcium-dependent domain containing 5 -3.80363
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.78274
FOXM1 forkhead box M1 -3.69273
TIMELESS timeless circadian clock -3.6841
SPAG7 sperm associated antigen 7 -3.63931
MELK maternal embryonic leucine zipper kinase -3.63328
PHF2 PHD finger protein 2 -3.58062
POLE polymerase (DNA directed), epsilon, catalytic subunit -3.52761
ECH1 enoyl CoA hydratase 1, peroxisomal -3.51484
HADH hydroxyacyl-CoA dehydrogenase -3.39362
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.38309
CCNB2 cyclin B2 -3.37284
CDCA8 cell division cycle associated 8 -3.36887
PCCB propionyl CoA carboxylase, beta polypeptide -3.36611
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.36018
CASC3 cancer susceptibility candidate 3 -3.35153
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.33394
CHAF1A chromatin assembly factor 1, subunit A (p150) -3.33344
PROS1 protein S (alpha) -3.31355
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.28968
SCCPDH saccharopine dehydrogenase (putative) -3.2698
THOC1 THO complex 1 -3.26073
MYO19 myosin XIX -3.23348
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -3.20928
NUP88 nucleoporin 88kDa -3.20826
POLK polymerase (DNA directed) kappa -3.1958
TTK TTK protein kinase -3.1647
CDC25A cell division cycle 25A -3.15936
KIF15 kinesin family member 15 -3.13435
ITGB1BP1 integrin beta 1 binding protein 1 -3.10075
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.09956
POLR1A polymerase (RNA) I polypeptide A, 194kDa -3.08854
SLC35B1 solute carrier family 35, member B1 -3.08355
BCL7B B-cell CLL/lymphoma 7B -3.0558
SQOR sulfide quinone oxidoreductase -3.04587
GNAS GNAS complex locus -3.04396
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 -2.97803
F5 coagulation factor V (proaccelerin, labile factor) -2.94701
GPN1 GPN-loop GTPase 1 -2.93841
MYLK myosin light chain kinase -2.92926
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.92731
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -2.89498
NCAPH non-SMC condensin I complex, subunit H -2.87308
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -2.86803
FANCG Fanconi anemia, complementation group G -2.85953
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.81465
PPARG peroxisome proliferator-activated receptor gamma -2.80925
AURKA aurora kinase A -2.79317
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -2.79068
HJURP Holliday junction recognition protein -2.76706
NNT nicotinamide nucleotide transhydrogenase -2.75315
PSAT1 phosphoserine aminotransferase 1 -2.75161
ATMIN ATM interactor -2.71798
DCTD dCMP deaminase -2.69971
NDC80 NDC80 kinetochore complex component -2.69953
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -2.68931
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.63916
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.61958
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.60201
FBXO5 F-box protein 5 -2.59278
GALE UDP-galactose-4-epimerase -2.58989
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 -2.58049
RBM14-RBM4 RBM14-RBM4 readthrough -2.5608
KIF4A kinesin family member 4A -2.55961
SLC25A38 solute carrier family 25, member 38 -2.54678
MRPS16 mitochondrial ribosomal protein S16 -2.54463
SENP6 SUMO1/sentrin specific peptidase 6 -2.53843
C5 complement component 5 -2.52771
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -2.50928
CCDC91 coiled-coil domain containing 91 -2.50923
WEE1 WEE1 G2 checkpoint kinase -2.50638
USP1 ubiquitin specific peptidase 1 -2.50578
TRIB3 tribbles pseudokinase 3 -2.50274
RCC1L RCC1 like -2.50156
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.49045
VRK2 vaccinia related kinase 2 -2.48449
KRCC1 lysine-rich coiled-coil 1 -2.48352
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase -2.47829
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -2.47192
CYB5R2 cytochrome b5 reductase 2 -2.46959
AEBP1 AE binding protein 1 -2.46557
EXO1 exonuclease 1 -2.44483
CD48 CD48 molecule -2.44165
KIF14 kinesin family member 14 -2.42754
SUMO4 small ubiquitin-like modifier 4 -2.42062
RAD51AP1 RAD51 associated protein 1 -2.41817
PUF60 poly-U binding splicing factor 60KDa -2.41558
GCN1 GCN1 activator of EIF2AK4 -2.40372
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -2.40336
ZIM2 zinc finger, imprinted 2 -2.39702
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -2.39294
RAD51 RAD51 recombinase -2.37958
DEPDC1 DEP domain containing 1 -2.37643
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -2.36776
DENND4B DENN/MADD domain containing 4B -2.35738
VAV3 vav 3 guanine nucleotide exchange factor -2.35685
DPP3 dipeptidyl-peptidase 3 -2.35671
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.35488
FBXO7 F-box protein 7 -2.3535
EXOSC8 exosome component 8 -2.3525
HMGN3 high mobility group nucleosomal binding domain 3 -2.35013
PCNA proliferating cell nuclear antigen -2.34414
PTPN7 protein tyrosine phosphatase, non-receptor type 7 -2.32477
OXCT1 3-oxoacid CoA transferase 1 -2.31484
SELL selectin L -2.30626
PHKA1 phosphorylase kinase, alpha 1 (muscle) -2.30485
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -2.30221
USP9Y ubiquitin specific peptidase 9, Y-linked -2.29718
ATP9B ATPase, class II, type 9B -2.29447
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.29202
CCDC59 coiled-coil domain containing 59 -2.27255
SKA1 spindle and kinetochore associated complex subunit 1 -2.26676
METTL4 methyltransferase like 4 -2.26499
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.26456
SUMF2 sulfatase modifying factor 2 -2.26284
KRT13 keratin 13, type I -2.25904
RABL6 RAB, member RAS oncogene family-like 6 -2.25887
ZC3H14 zinc finger CCCH-type containing 14 -2.25864
MCM10 minichromosome maintenance complex component 10 -2.25234
CDT1 chromatin licensing and DNA replication factor 1 -2.24399
ACOT2 acyl-CoA thioesterase 2 -2.24185
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.24016
DBF4 DBF4 zinc finger -2.22342
TERT telomerase reverse transcriptase -2.22273
TARBP2 TAR (HIV-1) RNA binding protein 2 -2.21925
BIRC5 baculoviral IAP repeat containing 5 -2.21544
ZFY zinc finger protein, Y-linked -2.20871
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.20485
AP4M1 adaptor-related protein complex 4, mu 1 subunit -2.20428
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -2.20385
MSRA methionine sulfoxide reductase A -2.1995
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.1939
FANCI Fanconi anemia, complementation group I -2.19371
DSCC1 DNA replication and sister chromatid cohesion 1 -2.18904
NLGN4Y neuroligin 4, Y-linked -2.18754
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.18706
FANCC Fanconi anemia, complementation group C -2.18258
ACOD1 aconitate decarboxylase 1 -2.18149
MRPS30 mitochondrial ribosomal protein S30 -2.18051
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -2.17949
CCL19 chemokine (C-C motif) ligand 19 -2.17346
USP22 ubiquitin specific peptidase 22 -2.17246
ASGR2 asialoglycoprotein receptor 2 -2.17157
SHCBP1 SHC SH2-domain binding protein 1 -2.17075
KIF11 kinesin family member 11 -2.17032
CDC45 cell division cycle 45 -2.16677
KIF18B kinesin family member 18B -2.16565
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 -2.16528
IDE insulin-degrading enzyme -2.16455
FAM174C family with sequence similarity 174 member C -2.16441
COG2 component of oligomeric golgi complex 2 -2.15941
USP39 ubiquitin specific peptidase 39 -2.15845
TPM1 tropomyosin 1 (alpha) -2.15844
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.15746
HLA-DOB major histocompatibility complex, class II, DO beta -2.15735
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.15721
ZNF672 zinc finger protein 672 -2.156
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) -2.15465
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -2.13406
PTS 6-pyruvoyltetrahydropterin synthase -2.12593
TOP2A topoisomerase (DNA) II alpha 170kDa -2.12299
CRTAP cartilage associated protein -2.12068
GTSE1 G-2 and S-phase expressed 1 -2.12
FXYD3 FXYD domain containing ion transport regulator 3 -2.11984
CD2 CD2 molecule -2.11387
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.1121
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -2.11031
ECM2 extracellular matrix protein 2, female organ and adipocyte specific -2.10995
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -2.10462
ITM2A integral membrane protein 2A -2.10328
ZNF232 zinc finger protein 232 -2.10304
SIRPG signal-regulatory protein gamma -2.10297
DUT deoxyuridine triphosphatase -2.09934
ANOS1 anosmin 1 -2.09624
PLK4 polo-like kinase 4 -2.0922
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1 -2.09187
LRRC61 leucine rich repeat containing 61 -2.08869
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.08856
ABHD14A abhydrolase domain containing 14A -2.08668
ING3 inhibitor of growth family, member 3 -2.08668
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -2.08567
ICE2 interactor of little elongation complex ELL subunit 2 -2.08302
TRIP13 thyroid hormone receptor interactor 13 -2.07974
BHLHE41 basic helix-loop-helix family, member e41 -2.07762
TRAP1 TNF receptor-associated protein 1 -2.07713
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 -2.07671
CRTAM cytotoxic and regulatory T cell molecule -2.07671
GBE1 glucan (1,4-alpha-), branching enzyme 1 -2.07461
LMNB1 lamin B1 -2.06681
SCUBE2 signal peptide, CUB domain, EGF-like 2 -2.06628
KLF4 Kruppel-like factor 4 (gut) -2.06552
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -2.06461
MCM5 minichromosome maintenance complex component 5 -2.06103
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -2.05976
CDK7 cyclin-dependent kinase 7 -2.05626
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.04922
ETNK1 ethanolamine kinase 1 -2.0477
AURKB aurora kinase B -2.0453
ELAC2 elaC ribonuclease Z 2 -2.04511
SPAG4 sperm associated antigen 4 -2.04389
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 -2.04338
ITGB5 integrin, beta 5 -2.03746
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.02872
CLEC7A C-type lectin domain family 7, member A -2.0273
NFIL3 nuclear factor, interleukin 3 regulated -2.02404
RYR3 ryanodine receptor 3 -2.02239
RAD54L RAD54-like (S. cerevisiae) -2.01913
VRK1 vaccinia related kinase 1 -2.01911
BORA bora, aurora kinase A activator -2.01792
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -2.01518
PPP1R8 protein phosphatase 1, regulatory subunit 8 -2.0084
MTO1 mitochondrial tRNA translation optimization 1 -2.0074
CD3E CD3e molecule, epsilon (CD3-TCR complex) -2.00394
MANEA mannosidase, endo-alpha -2.00385
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -2.00322
CCL11 chemokine (C-C motif) ligand 11 -2.00036