CRCGN013_HEPG2_24H:K12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description vorinostat 0.63 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

415 genes differentially expressed following the CRCGN013_HEPG2_24H:K12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UBE2L6 ubiquitin-conjugating enzyme E2L 6 10.0
LCN2 lipocalin 2 6.71184
FOXO4 forkhead box O4 6.53722
LRP10 low density lipoprotein receptor-related protein 10 6.53577
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 6.42406
DNM1 dynamin 1 6.00212
CBR1 carbonyl reductase 1 5.77024
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 5.67759
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 5.44093
NPDC1 neural proliferation, differentiation and control, 1 5.13052
CCNF cyclin F 5.12926
ALDOC aldolase C, fructose-bisphosphate 4.87203
MYC v-myc avian myelocytomatosis viral oncogene homolog 4.53769
MVP major vault protein 4.53193
TIMP2 TIMP metallopeptidase inhibitor 2 4.21
HMG20B high mobility group 20B 4.2025
STIMATE STIM activating enhancer 4.19786
TIAM1 T-cell lymphoma invasion and metastasis 1 4.16109
GPER1 G protein-coupled estrogen receptor 1 4.02192
ADRB2 adrenoceptor beta 2, surface 4.01481
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 4.00099
PLS1 plastin 1 3.92716
SKIC2 SKI2 subunit of superkiller complex 3.82505
ANO10 anoctamin 10 3.80038
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.76091
REEP2 receptor accessory protein 2 3.62801
EPHB2 EPH receptor B2 3.56887
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 3.54486
ADGRE5 adhesion G protein-coupled receptor E5 3.47644
TCEA2 transcription elongation factor A (SII), 2 3.40656
DUSP6 dual specificity phosphatase 6 3.28292
PRCP prolylcarboxypeptidase (angiotensinase C) 3.17833
E2F2 E2F transcription factor 2 3.16664
SNPH syntaphilin 3.13108
TAC4 tachykinin 4 (hemokinin) 3.1123
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 3.09729
HDGFL3 HDGF like 3 3.0625
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 3.06111
DNAAF3 dynein, axonemal, assembly factor 3 3.05857
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 3.05259
PTPN12 protein tyrosine phosphatase, non-receptor type 12 3.02526
CRABP2 cellular retinoic acid binding protein 2 3.01532
DYNLT3 dynein, light chain, Tctex-type 3 3.00554
PTP4A3 protein tyrosine phosphatase type IVA, member 3 2.98551
TBXA2R thromboxane A2 receptor 2.9513
CGRRF1 cell growth regulator with ring finger domain 1 2.94595
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 2.85615
VAT1 vesicle amine transport 1 2.8416
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 2.84079
ARFIP2 ADP-ribosylation factor interacting protein 2 2.83695
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 2.82422
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 2.79724
CIAO3 cytosolic iron-sulfur assembly component 3 2.78247
FXYD7 FXYD domain containing ion transport regulator 7 2.77523
CLDN9 claudin 9 2.7749
FAT1 FAT atypical cadherin 1 2.76202
ASIC4 acid sensing (proton gated) ion channel family member 4 2.75763
CDC45 cell division cycle 45 2.75559
DOC2B double C2-like domains, beta 2.75065
AARS1 alanyl-tRNA synthetase 1 2.74669
SSBP2 single-stranded DNA binding protein 2 2.72543
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 2.724
TCF15 transcription factor 15 (basic helix-loop-helix) 2.72398
BMP4 bone morphogenetic protein 4 2.71031
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.6948
DENND2D DENN/MADD domain containing 2D 2.68652
FKBP14 FK506 binding protein 14, 22 kDa 2.67929
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 2.67302
HMX1 H6 family homeobox 1 2.67212
TUBB6 tubulin, beta 6 class V 2.66908
H2BC12 H2B clustered histone 12 2.65223
AMN amnion associated transmembrane protein 2.65172
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 2.64818
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.63482
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 2.62151
CDPF1 cysteine-rich, DPF motif domain containing 1 2.62015
PRSS22 protease, serine, 22 2.61505
ELAVL3 ELAV like neuron-specific RNA binding protein 3 2.61281
ACBD4 acyl-CoA binding domain containing 4 2.61083
ABHD6 abhydrolase domain containing 6 2.60363
FBXO2 F-box protein 2 2.58918
HLA-DMA major histocompatibility complex, class II, DM alpha 2.57493
OR3A3 olfactory receptor, family 3, subfamily A, member 3 2.57224
EHD2 EH-domain containing 2 2.56982
RNASE12 ribonuclease, RNase A family, 12 (non-active) 2.5579
ADGRL1 adhesion G protein-coupled receptor L1 2.55317
TRIM11 tripartite motif containing 11 2.54942
BBC3 BCL2 binding component 3 2.54784
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.54266
MCTS1 malignant T cell amplified sequence 1 2.54116
CLDN6 claudin 6 2.53438
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.53234
RAB3A RAB3A, member RAS oncogene family 2.51687
MAP3K10 mitogen-activated protein kinase kinase kinase 10 2.50983
CPNE7 copine VII 2.50215
ADAM10 ADAM metallopeptidase domain 10 2.49912
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 2.49238
PTPRN protein tyrosine phosphatase, receptor type, N 2.46366
HDAC7 histone deacetylase 7 2.46025
GPR162 G protein-coupled receptor 162 2.45886
TSHZ2 teashirt zinc finger homeobox 2 2.45109
RTN2 reticulon 2 2.45099
HSF4 heat shock transcription factor 4 2.44837
DNAAF8 dynein axonemal assembly factor 8 2.44466
HEYL hes-related family bHLH transcription factor with YRPW motif-like 2.4441
TLE6 transducin-like enhancer of split 6 2.4345
BAX BCL2-associated X protein 2.43336
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.43296
IKZF4 IKAROS family zinc finger 4 (Eos) 2.42683
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 2.42329
PNMA3 paraneoplastic Ma antigen 3 2.42244
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 2.41085
ADRA2C adrenoceptor alpha 2C 2.39657
CAMKV CaM kinase-like vesicle-associated 2.39521
IGFALS insulin-like growth factor binding protein, acid labile subunit 2.39296
FAM110D family with sequence similarity 110, member D 2.38892
MOK MOK protein kinase 2.37947
EXTL1 exostosin-like glycosyltransferase 1 2.37646
VCY1B variable charge, Y-linked 1B 2.37193
MACO1 macoilin 1 2.36903
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 2.3635
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 2.36308
EFNA3 ephrin-A3 2.34396
DOK4 docking protein 4 2.34258
SHISAL1 shisa like 1 2.3414
SHBG sex hormone-binding globulin 2.33557
DYNC2I1 dynein 2 intermediate chain 1 2.31801
MATN2 matrilin 2 2.30913
AHNAK2 AHNAK nucleoprotein 2 2.30794
PCDH1 protocadherin 1 2.3015
WNT6 wingless-type MMTV integration site family, member 6 2.3001
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 2.29714
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific 2.29549
DUX4 double homeobox 4 2.29296
KIF3C kinesin family member 3C 2.29214
REM1 RAS (RAD and GEM)-like GTP-binding 1 2.29072
NT5DC3 5'-nucleotidase domain containing 3 2.28874
MMP14 matrix metallopeptidase 14 (membrane-inserted) 2.28846
PADI1 peptidyl arginine deiminase, type I 2.28531
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8 2.28451
CYB561 cytochrome b561 2.27017
EPN2 epsin 2 2.26731
SSTR3 somatostatin receptor 3 2.26358
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 2.26145
PRLH prolactin releasing hormone 2.26078
IL22 interleukin 22 2.25841
TRPV5 transient receptor potential cation channel, subfamily V, member 5 2.25547
HABP4 hyaluronan binding protein 4 2.25349
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 2.24463
TBPL1 TBP-like 1 2.24162
NT5M 5',3'-nucleotidase, mitochondrial 2.23684
CCDC71 coiled-coil domain containing 71 2.23468
EGR1 early growth response 1 2.23333
GRK1 G protein-coupled receptor kinase 1 2.22512
NME7 NME/NM23 family member 7 2.22151
KIFC3 kinesin family member C3 2.22128
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 2.21738
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.21309
MTNR1B melatonin receptor 1B 2.20809
SERGEF secretion regulating guanine nucleotide exchange factor 2.20782
GPR45 G protein-coupled receptor 45 2.20467
PLD2 phospholipase D2 2.19857
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.19499
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma 2.18697
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.18592
ADM2 adrenomedullin 2 2.18052
RASL12 RAS-like, family 12 2.17616
LIM2 lens intrinsic membrane protein 2, 19kDa 2.17352
ENO2 enolase 2 (gamma, neuronal) 2.17164
MEF2B myocyte enhancer factor 2B 2.16939
IRS1 insulin receptor substrate 1 2.16449
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 2.1615
GDF2 growth differentiation factor 2 2.15925
FABP2 fatty acid binding protein 2, intestinal 2.1578
HYAL2 hyaluronoglucosaminidase 2 2.15476
ASIC1 acid sensing (proton gated) ion channel 1 2.15164
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 2.15137
CALU calumenin 2.14874
FRMPD4 FERM and PDZ domain containing 4 2.14464
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 2.14438
SFXN3 sideroflexin 3 2.1431
FOXH1 forkhead box H1 2.14165
CRYGC crystallin, gamma C 2.13941
RTL10 retrotransposon Gag like 10 2.13885
GOLGA6L9 golgin A6 family-like 9 2.13236
TPSG1 tryptase gamma 1 2.13232
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 2.13198
LGMN legumain 2.13088
SAMD4B sterile alpha motif domain containing 4B 2.13082
ABHD11 abhydrolase domain containing 11 2.1282
APEH acylaminoacyl-peptide hydrolase 2.12035
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 2.11942
GIPC1 GIPC PDZ domain containing family, member 1 2.11824
MNX1 motor neuron and pancreas homeobox 1 2.11579
OSTF1 osteoclast stimulating factor 1 2.115
CEND1 cell cycle exit and neuronal differentiation 1 2.10835
EVX1 even-skipped homeobox 1 2.09906
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 2.09814
MRC2 mannose receptor, C type 2 2.09277
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.0865
NR5A1 nuclear receptor subfamily 5, group A, member 1 2.08346
MAPK3 mitogen-activated protein kinase 3 2.08332
TSPO2 translocator protein 2 2.083
KDR kinase insert domain receptor 2.08151
MAP3K12 mitogen-activated protein kinase kinase kinase 12 2.0778
ACOT8 acyl-CoA thioesterase 8 2.07614
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.07553
IFI27 interferon, alpha-inducible protein 27 2.07533
PTMS parathymosin 2.07508
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 2.07405
ALX3 ALX homeobox 3 2.07194
SCGB1D1 secretoglobin, family 1D, member 1 2.06976
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 2.06905
CDH22 cadherin 22, type 2 2.06792
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 2.05697
ARMC7 armadillo repeat containing 7 2.05637
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 2.05188
FZD2 frizzled class receptor 2 2.048
FNDC4 fibronectin type III domain containing 4 2.04341
STXBP1 syntaxin binding protein 1 2.04329
AHR aryl hydrocarbon receptor 2.0408
CLSTN3 calsyntenin 3 2.04075
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.03488
PLAT plasminogen activator, tissue 2.03191
PLPPR2 phospholipid phosphatase related 2 2.02845
CNOT1 CCR4-NOT transcription complex, subunit 1 2.02827
TRIB1 tribbles pseudokinase 1 2.02488
CARMIL1 capping protein regulator and myosin 1 linker 1 2.0243
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 2.02316
NSG2 neuronal vesicle trafficking associated 2 2.02074
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 2.01566
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.01556
PGM5 phosphoglucomutase 5 2.01543
ATOSB atos homolog B 2.00733
RPA3 replication protein A3, 14kDa 2.0051
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 2.0049
RAX retina and anterior neural fold homeobox 2.00076

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -9.66102
ICAM3 intercellular adhesion molecule 3 -6.06166
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -6.04613
CD320 CD320 molecule -5.61811
PCNA proliferating cell nuclear antigen -5.38606
RPIA ribose 5-phosphate isomerase A -5.24947
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -5.10813
CASP7 caspase 7, apoptosis-related cysteine peptidase -5.02017
ISOC1 isochorismatase domain containing 1 -4.8899
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.72026
TMEM109 transmembrane protein 109 -4.69034
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -4.62517
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -4.62466
NGRN neugrin, neurite outgrowth associated -4.37001
CCNA2 cyclin A2 -4.24363
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -4.2227
PGM1 phosphoglucomutase 1 -4.08486
CHEK1 checkpoint kinase 1 -4.04706
KEAP1 kelch-like ECH-associated protein 1 -4.03556
LRRC41 leucine rich repeat containing 41 -3.91896
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.85877
TCERG1 transcription elongation regulator 1 -3.81671
CRELD2 cysteine-rich with EGF-like domains 2 -3.73391
ZNF586 zinc finger protein 586 -3.7186
TCTN1 tectonic family member 1 -3.68329
NUP85 nucleoporin 85kDa -3.64805
GLOD4 glyoxalase domain containing 4 -3.59646
CCNB1 cyclin B1 -3.57349
LOC124907782 dual specificity protein phosphatase 22 -3.54985
MSRA methionine sulfoxide reductase A -3.48164
DCK deoxycytidine kinase -3.35597
STAP2 signal transducing adaptor family member 2 -3.31194
PARP1 poly (ADP-ribose) polymerase 1 -3.29603
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.28816
TATDN2 TatD DNase domain containing 2 -3.27524
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.25379
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -3.2447
NUP62 nucleoporin 62kDa -3.23841
BCL7B B-cell CLL/lymphoma 7B -3.23484
ECH1 enoyl CoA hydratase 1, peroxisomal -3.19847
PLK1 polo-like kinase 1 -3.19762
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -3.17566
CASC3 cancer susceptibility candidate 3 -3.1547
RRAGA Ras-related GTP binding A -3.12525
RCC1L RCC1 like -3.10894
FAIM Fas apoptotic inhibitory molecule -3.10443
GTPBP8 GTP-binding protein 8 (putative) -3.0766
SPAG7 sperm associated antigen 7 -3.04446
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -3.03829
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -3.02634
NT5DC2 5'-nucleotidase domain containing 2 -3.01342
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.0105
PHF2 PHD finger protein 2 -2.95428
CDC25A cell division cycle 25A -2.94479
TMEM147 transmembrane protein 147 -2.93583
MCM5 minichromosome maintenance complex component 5 -2.93076
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.90412
TARBP2 TAR (HIV-1) RNA binding protein 2 -2.88345
KDM3A lysine (K)-specific demethylase 3A -2.87838
DERA deoxyribose-phosphate aldolase (putative) -2.87213
CDC25B cell division cycle 25B -2.8402
HRAS Harvey rat sarcoma viral oncogene homolog -2.82104
GNPDA1 glucosamine-6-phosphate deaminase 1 -2.80071
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -2.76457
ZBED1 zinc finger, BED-type containing 1 -2.69817
ATF5 activating transcription factor 5 -2.69787
MRM3 mitochondrial rRNA methyltransferase 3 -2.69499
AGMAT agmatine ureohydrolase (agmatinase) -2.69072
USP39 ubiquitin specific peptidase 39 -2.69028
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.68772
COPS7A COP9 signalosome subunit 7A -2.68592
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.67414
EGF epidermal growth factor -2.6552
REEP5 receptor accessory protein 5 -2.64841
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.63576
CCP110 centriolar coiled coil protein 110kDa -2.62963
RBM14-RBM4 RBM14-RBM4 readthrough -2.6205
UBE2C ubiquitin-conjugating enzyme E2C -2.6077
PCCB propionyl CoA carboxylase, beta polypeptide -2.60233
DCAF17 DDB1 and CUL4 associated factor 17 -2.59885
POLA2 polymerase (DNA directed), alpha 2, accessory subunit -2.5865
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -2.58443
SOAT2 sterol O-acyltransferase 2 -2.56692
AURKB aurora kinase B -2.56561
MAPK13 mitogen-activated protein kinase 13 -2.55473
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) -2.5267
LYRM1 LYR motif containing 1 -2.5212
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.51847
ZDHHC6 zinc finger, DHHC-type containing 6 -2.51321
MRPS2 mitochondrial ribosomal protein S2 -2.49014
USP1 ubiquitin specific peptidase 1 -2.4884
TTC4 tetratricopeptide repeat domain 4 -2.4807
TRAF1 TNF receptor-associated factor 1 -2.47505
TM9SF3 transmembrane 9 superfamily member 3 -2.4518
PPP1R8 protein phosphatase 1, regulatory subunit 8 -2.44896
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.44701
FANCG Fanconi anemia, complementation group G -2.43454
NELFB negative elongation factor complex member B -2.42429
TBCB tubulin folding cofactor B -2.41162
QDPR quinoid dihydropteridine reductase -2.39165
SDF4 stromal cell derived factor 4 -2.37956
NNT nicotinamide nucleotide transhydrogenase -2.37117
MB myoglobin -2.35769
ATMIN ATM interactor -2.34288
FBXO7 F-box protein 7 -2.33596
ATAD2B ATPase family, AAA domain containing 2B -2.30985
CDK1 cyclin-dependent kinase 1 -2.3022
FGR FGR proto-oncogene, Src family tyrosine kinase -2.29676
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 -2.29419
CAB39 calcium binding protein 39 -2.27732
DCTD dCMP deaminase -2.27301
THOP1 thimet oligopeptidase 1 -2.27147
CPNE3 copine III -2.26681
TOR1A torsin family 1, member A (torsin A) -2.26099
EXOSC8 exosome component 8 -2.26041
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.25632
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 -2.25618
FOXM1 forkhead box M1 -2.24627
PROS1 protein S (alpha) -2.24456
FGFR4 fibroblast growth factor receptor 4 -2.24146
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase -2.23461
TMEM11 transmembrane protein 11 -2.23431
CAPN3 calpain 3, (p94) -2.23117
ENO3 enolase 3 (beta, muscle) -2.22615
MCM10 minichromosome maintenance complex component 10 -2.22374
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) -2.22303
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -2.20774
CAPNS1 calpain, small subunit 1 -2.20711
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic -2.18881
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 -2.18169
MELK maternal embryonic leucine zipper kinase -2.18133
MRPS16 mitochondrial ribosomal protein S16 -2.18109
MRPL39 mitochondrial ribosomal protein L39 -2.17659
TTK TTK protein kinase -2.16964
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.16867
CCT7 chaperonin containing TCP1, subunit 7 (eta) -2.16593
FAM193A family with sequence similarity 193, member A -2.16534
AURKA aurora kinase A -2.16392
TSPAN8 tetraspanin 8 -2.1637
CDK4 cyclin-dependent kinase 4 -2.15525
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -2.15042
PRPF4 pre-mRNA processing factor 4 -2.15014
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 -2.145
POLR1A polymerase (RNA) I polypeptide A, 194kDa -2.1435
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -2.13426
MYBPC1 myosin binding protein C, slow type -2.12872
SCCPDH saccharopine dehydrogenase (putative) -2.12561
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa -2.12328
PHF11 PHD finger protein 11 -2.12322
GPN1 GPN-loop GTPase 1 -2.11675
SNX11 sorting nexin 11 -2.11367
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -2.11212
TLCD3A TLC domain containing 3A -2.10689
RFC3 replication factor C (activator 1) 3, 38kDa -2.10091
TIMELESS timeless circadian clock -2.09369
SHCBP1 SHC SH2-domain binding protein 1 -2.08922
SMYD5 SMYD family member 5 -2.08634
MCM7 minichromosome maintenance complex component 7 -2.08021
SF3A1 splicing factor 3a, subunit 1, 120kDa -2.07417
ENTR1 endosome associated trafficking regulator 1 -2.06554
DPP8 dipeptidyl-peptidase 8 -2.05743
DEPDC1 DEP domain containing 1 -2.05068
C2CD5 C2 calcium-dependent domain containing 5 -2.0484
KRCC1 lysine-rich coiled-coil 1 -2.04588
NUP43 nucleoporin 43kDa -2.04497
USP11 ubiquitin specific peptidase 11 -2.04176
ZMIZ1 zinc finger, MIZ-type containing 1 -2.03858
CRTC3 CREB regulated transcription coactivator 3 -2.03612
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -2.03307
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.02666
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.0213
SPAG4 sperm associated antigen 4 -2.01947
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.01516
CDC6 cell division cycle 6 -2.01394
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -2.01338
PUM2 pumilio RNA-binding family member 2 -2.01154
BLCAP bladder cancer associated protein -2.00677
SLC67A2 solute carrier family 67 member 2 -2.00544