| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMBA 9.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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73 genes differentially expressed following the CRCGN013_HEPG2_24H:K15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 10.0 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 10.0 |
| LCN2 | lipocalin 2 | 5.61259 |
| ZNF589 | zinc finger protein 589 | 5.10129 |
| ABHD4 | abhydrolase domain containing 4 | 4.87795 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.49879 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.87507 |
| NOTCH1 | notch 1 | 3.83538 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.80382 |
| CCNF | cyclin F | 3.68076 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.54772 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.25265 |
| BZW2 | basic leucine zipper and W2 domains 2 | 3.23347 |
| CHMP6 | charged multivesicular body protein 6 | 3.17151 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 3.1556 |
| MOK | MOK protein kinase | 3.07301 |
| PNKP | polynucleotide kinase 3'-phosphatase | 3.0722 |
| ATP11B | ATPase, class VI, type 11B | 3.04128 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 3.035 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 3.01513 |
| TXNRD1 | thioredoxin reductase 1 | 2.92778 |
| GATA2 | GATA binding protein 2 | 2.86285 |
| KIFBP | kinesin family binding protein | 2.79279 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.78732 |
| INPP1 | inositol polyphosphate-1-phosphatase | 2.78395 |
| FOSL1 | FOS-like antigen 1 | 2.63566 |
| TUBB6 | tubulin, beta 6 class V | 2.59928 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.58933 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.37054 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.34475 |
| HYAL2 | hyaluronoglucosaminidase 2 | 2.31438 |
| MYLK | myosin light chain kinase | 2.22449 |
| NANOS3 | nanos homolog 3 (Drosophila) | 2.2038 |
| MICALL1 | MICAL-like 1 | 2.20278 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.15939 |
| FZD1 | frizzled class receptor 1 | 2.11561 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 | 2.10053 |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 | 2.08178 |
| BAX | BCL2-associated X protein | 2.06964 |
| PRKCH | protein kinase C, eta | 2.05299 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZW10 | zw10 kinetochore protein | -5.13366 |
| PCNA | proliferating cell nuclear antigen | -4.9658 |
| C5 | complement component 5 | -4.23301 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.23274 |
| LOC124907782 | dual specificity protein phosphatase 22 | -4.17276 |
| ADI1 | acireductone dioxygenase 1 | -3.70266 |
| FASTKD5 | FAST kinase domains 5 | -3.60226 |
| CCNB1 | cyclin B1 | -3.42763 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.40255 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.38818 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.32949 |
| LDHD | lactate dehydrogenase D | -3.30132 |
| PEG10 | paternally expressed 10 | -3.24397 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -3.17955 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.91442 |
| DNM1L | dynamin 1-like | -2.85134 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -2.65559 |
| PDHX | pyruvate dehydrogenase complex, component X | -2.65486 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.65054 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | -2.6352 |
| MSRA | methionine sulfoxide reductase A | -2.46255 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -2.46214 |
| EGF | epidermal growth factor | -2.42892 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.41151 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.41088 |
| TCTN1 | tectonic family member 1 | -2.39017 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | -2.24067 |
| ANO10 | anoctamin 10 | -2.2325 |
| SNX11 | sorting nexin 11 | -2.2243 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -2.17567 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.11482 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.01316 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -2.0023 |
