| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMBA 2.48 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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82 genes differentially expressed following the CRCGN013_HEPG2_24H:K17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 6.59685 |
| UBQLN2 | ubiquilin 2 | 6.47204 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 4.49776 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.49307 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.4353 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 4.40604 |
| CNPY3 | canopy FGF signaling regulator 3 | 4.28088 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.05995 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.68123 |
| CCDC92 | coiled-coil domain containing 92 | 3.56145 |
| TBP | TATA box binding protein | 3.52001 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 3.24683 |
| E2F2 | E2F transcription factor 2 | 3.18897 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.06898 |
| CYCS | cytochrome c, somatic | 3.0668 |
| HSPA1A | heat shock 70kDa protein 1A | 3.06513 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 2.93465 |
| ABHD4 | abhydrolase domain containing 4 | 2.85077 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.83239 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.82069 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.7811 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 2.76365 |
| MAMLD1 | mastermind-like domain containing 1 | 2.76303 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.65714 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.61681 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.60746 |
| TUBB6 | tubulin, beta 6 class V | 2.56585 |
| RNF34 | ring finger protein 34, E3 ubiquitin protein ligase | 2.49496 |
| TXNRD1 | thioredoxin reductase 1 | 2.35877 |
| PRKCH | protein kinase C, eta | 2.33908 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.31538 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 2.29261 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.2625 |
| FOSL1 | FOS-like antigen 1 | 2.20928 |
| GPX7 | glutathione peroxidase 7 | 2.17534 |
| ODF2 | outer dense fiber of sperm tails 2 | 2.17373 |
| LRP10 | low density lipoprotein receptor-related protein 10 | 2.15846 |
| PRKCD | protein kinase C, delta | 2.13138 |
| TSPAN14 | tetraspanin 14 | 2.1262 |
| KLF2 | Kruppel-like factor 2 | 2.1037 |
| LOC124907090 | ankyrin repeat domain-containing protein SOWAHC-like | 2.10359 |
| CHPT1 | choline phosphotransferase 1 | 2.04152 |
| NPPB | natriuretic peptide B | 2.01021 |
| TSPAN6 | tetraspanin 6 | 2.00041 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB1 | cyclin B1 | -5.0181 |
| CCNB2 | cyclin B2 | -4.90225 |
| HMG20B | high mobility group 20B | -4.82725 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.25418 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -4.02998 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -3.95455 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -3.53033 |
| EDN1 | endothelin 1 | -3.47596 |
| CTSD | cathepsin D | -3.40494 |
| MAP7 | microtubule-associated protein 7 | -3.31441 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -3.15304 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.98925 |
| PCNA | proliferating cell nuclear antigen | -2.94448 |
| ZNF586 | zinc finger protein 586 | -2.93786 |
| LDHD | lactate dehydrogenase D | -2.93144 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.89935 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.75835 |
| EXT1 | exostosin glycosyltransferase 1 | -2.67786 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.63499 |
| MSRA | methionine sulfoxide reductase A | -2.63354 |
| ADI1 | acireductone dioxygenase 1 | -2.61059 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.55056 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -2.48506 |
| TLCD3A | TLC domain containing 3A | -2.46666 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.45181 |
| FHL2 | four and a half LIM domains 2 | -2.34668 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.31549 |
| FKBP4 | FK506 binding protein 4, 59kDa | -2.28626 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.18745 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.17725 |
| SNX11 | sorting nexin 11 | -2.1765 |
| CCDC86 | coiled-coil domain containing 86 | -2.11292 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.11062 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.10873 |
| TENT4A | terminal nucleotidyltransferase 4A | -2.0582 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | -2.05205 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 | -2.02443 |
| DENND1B | DENN/MADD domain containing 1B | -2.00062 |
