CRCGN013_HEPG2_24H:K19 Gene Set
Genes
41 genes differentially expressed following the CRCGN013_HEPG2_24H:K19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PRR15L
|
proline rich 15-like
|
4.46324
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.62773
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.34932
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.33888
|
|
LCN2
|
lipocalin 2
|
3.2337
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.17592
|
|
UBQLN2
|
ubiquilin 2
|
3.11954
|
|
MYLK
|
myosin light chain kinase
|
3.07435
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.04585
|
|
CCNH
|
cyclin H
|
2.92173
|
|
CCNA1
|
cyclin A1
|
2.90177
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.86928
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.77452
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.74368
|
|
GATA3
|
GATA binding protein 3
|
2.45456
|
|
CYCS
|
cytochrome c, somatic
|
2.43463
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.37149
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.31589
|
|
STXBP1
|
syntaxin binding protein 1
|
2.25872
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.19384
|
|
ANO10
|
anoctamin 10
|
2.13648
|
|
SATB1
|
SATB homeobox 1
|
2.0934
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.00297
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.99672
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.32626
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.67493
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.5422
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.15253
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.0134
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.96874
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.95499
|
|
PLK1
|
polo-like kinase 1
|
-2.92086
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.83665
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
-2.80269
|
|
FBXO7
|
F-box protein 7
|
-2.66907
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.58725
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.54485
|
|
GNAS
|
GNAS complex locus
|
-2.3937
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.38629
|
|
CCNB2
|
cyclin B2
|
-2.33538
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.1497
|
