CRCGN013_HEPG2_24H:K20 Gene Set
Genes
46 genes differentially expressed following the CRCGN013_HEPG2_24H:K20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
6.70893
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
6.22035
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
5.4843
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
5.32995
|
|
MYLK
|
myosin light chain kinase
|
4.14838
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.63536
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.47481
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.46017
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.45808
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.45715
|
|
IDE
|
insulin-degrading enzyme
|
3.33927
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.23184
|
|
E2F2
|
E2F transcription factor 2
|
3.20915
|
|
HDGFL3
|
HDGF like 3
|
3.06728
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.9
|
|
CHN1
|
chimerin 1
|
2.86978
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.8345
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.69823
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.68768
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.48162
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.47711
|
|
NOTCH1
|
notch 1
|
2.40216
|
|
HEBP1
|
heme binding protein 1
|
2.23899
|
|
BCKDHA
|
branched chain keto acid dehydrogenase E1, alpha polypeptide
|
2.13787
|
|
FOXD1
|
forkhead box D1
|
2.0526
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MAPK13
|
mitogen-activated protein kinase 13
|
-7.40413
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-6.98671
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.93185
|
|
CCNB2
|
cyclin B2
|
-4.71785
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.45376
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.72269
|
|
CDC20
|
cell division cycle 20
|
-3.45061
|
|
ELAC2
|
elaC ribonuclease Z 2
|
-3.31609
|
|
LDHD
|
lactate dehydrogenase D
|
-3.20177
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-3.02489
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
-2.82886
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.78542
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.66275
|
|
EXT1
|
exostosin glycosyltransferase 1
|
-2.64523
|
|
WDR7
|
WD repeat domain 7
|
-2.54809
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.29429
|
|
MYBL2
|
v-myb avian myeloblastosis viral oncogene homolog-like 2
|
-2.2596
|
|
PLK1
|
polo-like kinase 1
|
-2.19673
|
|
MOB3B
|
MOB kinase activator 3B
|
-2.14479
|
|
ALAS2
|
5'-aminolevulinate synthase 2
|
-2.12896
|
|
ZDHHC4
|
zinc finger, DHHC-type containing 4
|
-2.01859
|
