CRCGN013_HEPG2_24H:K21 Gene Set
Genes
41 genes differentially expressed following the CRCGN013_HEPG2_24H:K21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHN1
|
chimerin 1
|
4.80073
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.3784
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.74394
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.50025
|
|
CYCS
|
cytochrome c, somatic
|
3.26725
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.11821
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
3.08202
|
|
JADE2
|
jade family PHD finger 2
|
3.02359
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.96792
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.90512
|
|
SATB1
|
SATB homeobox 1
|
2.84128
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.64996
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.63863
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.48654
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.3556
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.11827
|
|
CEP57
|
centrosomal protein 57kDa
|
2.06315
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.02169
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.99007
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.93075
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-4.17961
|
|
THAP11
|
THAP domain containing 11
|
-3.5251
|
|
SCAND1
|
SCAN domain containing 1
|
-3.49377
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.36613
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.18315
|
|
ZNF586
|
zinc finger protein 586
|
-3.14011
|
|
COG2
|
component of oligomeric golgi complex 2
|
-3.04982
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.91041
|
|
SNX11
|
sorting nexin 11
|
-2.88209
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.71636
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-2.67107
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.56322
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.46859
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.3745
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.19326
|
|
DSTN
|
destrin (actin depolymerizing factor)
|
-2.1616
|
|
PLA2G6
|
phospholipase A2, group VI (cytosolic, calcium-independent)
|
-2.14188
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.09711
|
|
CST8
|
cystatin 8 (cystatin-related epididymal specific)
|
-2.09642
|
|
KLC3
|
kinesin light chain 3
|
-2.03937
|
|
STAB2
|
stabilin 2
|
-2.02605
|
