CRCGN013_HEPG2_24H:K23 Gene Set
Genes
46 genes differentially expressed following the CRCGN013_HEPG2_24H:K23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
6.41077
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
6.32356
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.67242
|
|
MYLK
|
myosin light chain kinase
|
4.56878
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.14233
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.20167
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.85783
|
|
CYCS
|
cytochrome c, somatic
|
2.8351
|
|
CHN1
|
chimerin 1
|
2.77976
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.76461
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
2.67234
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.6325
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.61418
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.43012
|
|
KIFBP
|
kinesin family binding protein
|
2.4039
|
|
GATA2
|
GATA binding protein 2
|
2.19274
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.16316
|
|
IFIT1
|
interferon-induced protein with tetratricopeptide repeats 1
|
2.13856
|
|
IFI44L
|
interferon-induced protein 44-like
|
2.06238
|
|
TLR4
|
toll-like receptor 4
|
2.04089
|
|
OAS2
|
2'-5'-oligoadenylate synthetase 2, 69/71kDa
|
2.03618
|
|
LHFPL2
|
lipoma HMGIC fusion partner-like 2
|
2.00701
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-6.93134
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-6.04816
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-4.9696
|
|
DNM1L
|
dynamin 1-like
|
-4.95672
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.86183
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.56633
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-4.49977
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-4.33016
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.28401
|
|
CDC20
|
cell division cycle 20
|
-4.08945
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.6626
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.34568
|
|
HEATR1
|
HEAT repeat containing 1
|
-3.29721
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.25617
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-3.14226
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.11796
|
|
GNAS
|
GNAS complex locus
|
-3.09707
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.97449
|
|
CDC25B
|
cell division cycle 25B
|
-2.87657
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.57198
|
|
HMG20B
|
high mobility group 20B
|
-2.31147
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.26382
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.24129
|
|
NCOA4
|
nuclear receptor coactivator 4
|
-2.01142
|
