CRCGN013_HEPG2_24H:K24 Gene Set
Genes
50 genes differentially expressed following the CRCGN013_HEPG2_24H:K24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
5.46904
|
|
NOTCH1
|
notch 1
|
4.99258
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.9548
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.93117
|
|
CBR3
|
carbonyl reductase 3
|
4.89062
|
|
E2F2
|
E2F transcription factor 2
|
4.76954
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.59761
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
4.30301
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.2952
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.76794
|
|
MEF2C
|
myocyte enhancer factor 2C
|
3.75702
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.61389
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.60027
|
|
CHN1
|
chimerin 1
|
3.59833
|
|
PRR15L
|
proline rich 15-like
|
3.27486
|
|
IGHMBP2
|
immunoglobulin mu binding protein 2
|
2.87489
|
|
JADE2
|
jade family PHD finger 2
|
2.73747
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.72841
|
|
GPR18
|
G protein-coupled receptor 18
|
2.62377
|
|
GPATCH8
|
G patch domain containing 8
|
2.53622
|
|
CYCS
|
cytochrome c, somatic
|
2.53502
|
|
WASF3
|
WAS protein family, member 3
|
2.49775
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.38868
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.37944
|
|
CTLA4
|
cytotoxic T-lymphocyte-associated protein 4
|
2.24943
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.18922
|
|
COL11A1
|
collagen, type XI, alpha 1
|
2.05809
|
|
TNS3
|
tensin 3
|
2.02877
|
|
BFSP2
|
beaded filament structural protein 2, phakinin
|
2.0142
|
|
SYN1
|
synapsin I
|
2.01402
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-9.60669
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-5.29908
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-5.10905
|
|
RPN1
|
ribophorin I
|
-4.88824
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.62852
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-4.56179
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.48485
|
|
GNAS
|
GNAS complex locus
|
-3.50481
|
|
NVL
|
nuclear VCP-like
|
-2.85489
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.62906
|
|
TMEM230
|
transmembrane protein 230
|
-2.54964
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.54754
|
|
COPG1
|
coatomer protein complex, subunit gamma 1
|
-2.5057
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
-2.31165
|
|
PANK2
|
pantothenate kinase 2
|
-2.29456
|
|
DDRGK1
|
DDRGK domain containing 1
|
-2.15884
|
|
SOX12
|
SRY (sex determining region Y)-box 12
|
-2.10509
|
|
SENP6
|
SUMO1/sentrin specific peptidase 6
|
-2.04877
|
|
NSMF
|
NMDA receptor synaptonuclear signaling and neuronal migration factor
|
-2.02296
|
|
ZNF133
|
zinc finger protein 133
|
-2.01986
|
