CRCGN013_HEPG2_24H:L01 Gene Set
Genes
54 genes differentially expressed following the CRCGN013_HEPG2_24H:L01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MOK
|
MOK protein kinase
|
3.9716
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.777
|
|
LCN2
|
lipocalin 2
|
3.72726
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
3.66866
|
|
STK10
|
serine/threonine kinase 10
|
3.63688
|
|
NOTCH1
|
notch 1
|
3.43078
|
|
CBR3
|
carbonyl reductase 3
|
3.41418
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.32153
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.2705
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.96307
|
|
FZD7
|
frizzled class receptor 7
|
2.87856
|
|
CYCS
|
cytochrome c, somatic
|
2.78181
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
2.75689
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.7205
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.70051
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.66805
|
|
CEP57
|
centrosomal protein 57kDa
|
2.49106
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.45057
|
|
NENF
|
neudesin neurotrophic factor
|
2.36688
|
|
SIRT3
|
sirtuin 3
|
2.34307
|
|
TBP
|
TATA box binding protein
|
2.32039
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.25762
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.13082
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.08204
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.07225
|
|
LSM2
|
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
2.0104
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-5.04232
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.7631
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.29957
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-4.12017
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.05963
|
|
LDHD
|
lactate dehydrogenase D
|
-3.96445
|
|
RAI14
|
retinoic acid induced 14
|
-3.54253
|
|
CDC20
|
cell division cycle 20
|
-3.51357
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-3.29525
|
|
CCNB1
|
cyclin B1
|
-3.20399
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.02819
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.93829
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
-2.87195
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.75375
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
-2.73182
|
|
EVL
|
Enah/Vasp-like
|
-2.48421
|
|
ZNF586
|
zinc finger protein 586
|
-2.37091
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.31961
|
|
MYRIP
|
myosin VIIA and Rab interacting protein
|
-2.2787
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
-2.23897
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.22884
|
|
EGF
|
epidermal growth factor
|
-2.21032
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.11721
|
|
TCTA
|
T-cell leukemia translocation altered
|
-2.06546
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-2.06134
|
|
TLR4
|
toll-like receptor 4
|
-2.06016
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.05894
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.05216
|
