CRCGN013_HEPG2_24H:L02 Gene Set
Genes
47 genes differentially expressed following the CRCGN013_HEPG2_24H:L02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
6.91597
|
|
LCN2
|
lipocalin 2
|
4.2448
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.04027
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.8879
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
3.72111
|
|
NOTCH1
|
notch 1
|
3.52833
|
|
ANO10
|
anoctamin 10
|
3.27384
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.17837
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.02067
|
|
UBQLN2
|
ubiquilin 2
|
2.98501
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.87345
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.83483
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.4851
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.45494
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.36912
|
|
COPS5
|
COP9 signalosome subunit 5
|
2.27708
|
|
SNX7
|
sorting nexin 7
|
2.17934
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.15743
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.12202
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.00963
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC35F2
|
solute carrier family 35, member F2
|
-5.68761
|
|
CDC20
|
cell division cycle 20
|
-4.59392
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-4.57894
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.76517
|
|
THAP11
|
THAP domain containing 11
|
-3.62541
|
|
CD320
|
CD320 molecule
|
-3.53604
|
|
HAT1
|
histone acetyltransferase 1
|
-3.46303
|
|
CAB39
|
calcium binding protein 39
|
-3.28936
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.23954
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.23273
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.16224
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.15507
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.15505
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.99775
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.87956
|
|
TCERG1
|
transcription elongation regulator 1
|
-2.72665
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.63375
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.4954
|
|
RAI14
|
retinoic acid induced 14
|
-2.4837
|
|
TLR4
|
toll-like receptor 4
|
-2.47533
|
|
GNAS
|
GNAS complex locus
|
-2.41802
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.4096
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.29082
|
|
WASHC4
|
WASH complex subunit 4
|
-2.18995
|
|
SNX11
|
sorting nexin 11
|
-2.09002
|
|
EGF
|
epidermal growth factor
|
-2.03654
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.01371
|
