CRCGN013_HEPG2_24H:L04 Gene Set
Genes
54 genes differentially expressed following the CRCGN013_HEPG2_24H:L04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.88439
|
|
FZD7
|
frizzled class receptor 7
|
5.52354
|
|
UBQLN2
|
ubiquilin 2
|
4.91619
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.80922
|
|
HOXA10
|
homeobox A10
|
4.44347
|
|
NOTCH1
|
notch 1
|
3.93255
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.88157
|
|
LCN2
|
lipocalin 2
|
3.7418
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.55734
|
|
TCTA
|
T-cell leukemia translocation altered
|
3.32415
|
|
CHN1
|
chimerin 1
|
3.3175
|
|
EPHB2
|
EPH receptor B2
|
3.27079
|
|
SMIM40
|
small integral membrane protein 40
|
3.17129
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.16163
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.1423
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.74619
|
|
RETREG3
|
reticulophagy regulator family member 3
|
2.69135
|
|
CCNF
|
cyclin F
|
2.66929
|
|
MAP7
|
microtubule-associated protein 7
|
2.60885
|
|
NANOS2
|
nanos homolog 2 (Drosophila)
|
2.50933
|
|
KCND1
|
potassium channel, voltage gated Shal related subfamily D, member 1
|
2.31834
|
|
SLC4A1AP
|
solute carrier family 4 (anion exchanger), member 1, adaptor protein
|
2.25889
|
|
JADE2
|
jade family PHD finger 2
|
2.1916
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.17663
|
|
ACP2
|
acid phosphatase 2, lysosomal
|
2.17647
|
|
DUOX2
|
dual oxidase 2
|
2.13554
|
|
RPAP1
|
RNA polymerase II associated protein 1
|
2.06758
|
|
SPATA5L1
|
spermatogenesis associated 5-like 1
|
2.05265
|
|
CHRNA5
|
cholinergic receptor, nicotinic, alpha 5 (neuronal)
|
2.01755
|
|
MAIP1
|
matrix AAA peptidase interacting protein 1
|
2.01691
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-8.75918
|
|
PCNA
|
proliferating cell nuclear antigen
|
-7.39096
|
|
ENOPH1
|
enolase-phosphatase 1
|
-5.63911
|
|
CDC20
|
cell division cycle 20
|
-5.0
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.9808
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.96563
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-4.83325
|
|
ZNF586
|
zinc finger protein 586
|
-4.55607
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.39744
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-4.00187
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.32939
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.3096
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.3022
|
|
ZW10
|
zw10 kinetochore protein
|
-2.89438
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.73816
|
|
CD320
|
CD320 molecule
|
-2.52524
|
|
MUTYH
|
mutY homolog
|
-2.12646
|
|
TMC5
|
transmembrane channel-like 5
|
-2.09723
|
|
AGAP1
|
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
|
-2.09071
|
|
IST1
|
increased sodium tolerance 1 homolog (yeast)
|
-2.07154
|
|
SLC41A3
|
solute carrier family 41, member 3
|
-2.0604
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.0566
|
|
S100A9
|
S100 calcium binding protein A9
|
-2.02568
|
|
TCERG1
|
transcription elongation regulator 1
|
-2.01936
|
