CRCGN013_HEPG2_24H:L05 Gene Set
Genes
53 genes differentially expressed following the CRCGN013_HEPG2_24H:L05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
6.8962
|
|
GPATCH8
|
G patch domain containing 8
|
4.67736
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.56728
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.40066
|
|
UBQLN2
|
ubiquilin 2
|
4.31684
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
4.08383
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.03973
|
|
PMM2
|
phosphomannomutase 2
|
3.97604
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.91549
|
|
CHN1
|
chimerin 1
|
3.7685
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.72243
|
|
CEP57
|
centrosomal protein 57kDa
|
3.63361
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.48964
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.47669
|
|
STXBP2
|
syntaxin binding protein 2
|
3.2822
|
|
SFTPB
|
surfactant protein B
|
3.06958
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.7326
|
|
BAD
|
BCL2-associated agonist of cell death
|
2.5696
|
|
FOXD1
|
forkhead box D1
|
2.55352
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.52163
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.35376
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.30697
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.27507
|
|
CCNH
|
cyclin H
|
2.15114
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.14345
|
|
CEBPG
|
CCAAT/enhancer binding protein (C/EBP), gamma
|
2.1389
|
|
PIGB
|
phosphatidylinositol glycan anchor biosynthesis, class B
|
2.06096
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DSG2
|
desmoglein 2
|
-5.88758
|
|
LDHD
|
lactate dehydrogenase D
|
-5.7938
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.14153
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.49403
|
|
GDF15
|
growth differentiation factor 15
|
-4.27442
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-4.06625
|
|
EGF
|
epidermal growth factor
|
-3.54548
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-3.51929
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.38325
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.32017
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-3.25713
|
|
MLPH
|
melanophilin
|
-2.71102
|
|
VAT1
|
vesicle amine transport 1
|
-2.55785
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.3717
|
|
HMG20B
|
high mobility group 20B
|
-2.36669
|
|
CCNB1
|
cyclin B1
|
-2.3276
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.31745
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.31
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-2.27926
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.26514
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.18858
|
|
RBM47
|
RNA binding motif protein 47
|
-2.16708
|
|
MSMB
|
microseminoprotein, beta-
|
-2.16437
|
|
GET1
|
guided entry of tail-anchored proteins factor 1
|
-2.13264
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.10038
|
|
ILK
|
integrin-linked kinase
|
-2.03118
|
