CRCGN013_HEPG2_24H:L06 Gene Set
Genes
49 genes differentially expressed following the CRCGN013_HEPG2_24H:L06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.09512
|
|
MAP7
|
microtubule-associated protein 7
|
3.80087
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.73514
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.72792
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.55618
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.50059
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.46573
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.46048
|
|
ZFP36
|
ZFP36 ring finger protein
|
3.12914
|
|
NOTCH1
|
notch 1
|
3.0832
|
|
UBE2A
|
ubiquitin-conjugating enzyme E2A
|
2.69205
|
|
TBP
|
TATA box binding protein
|
2.64077
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.5738
|
|
CHN1
|
chimerin 1
|
2.54317
|
|
ZNF589
|
zinc finger protein 589
|
2.49275
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.40433
|
|
SNX7
|
sorting nexin 7
|
2.39186
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.32445
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.3202
|
|
ABHD4
|
abhydrolase domain containing 4
|
2.31427
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.26235
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.16149
|
|
SMIM40
|
small integral membrane protein 40
|
2.15813
|
|
KCNK5
|
potassium channel, two pore domain subfamily K, member 5
|
2.09589
|
|
ZNF318
|
zinc finger protein 318
|
2.06378
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.82777
|
|
GNAS
|
GNAS complex locus
|
-4.86949
|
|
TERF2IP
|
telomeric repeat binding factor 2, interacting protein
|
-3.98941
|
|
CCNB2
|
cyclin B2
|
-3.80766
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-3.80293
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.7339
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.66097
|
|
CCNB1
|
cyclin B1
|
-3.60149
|
|
CD320
|
CD320 molecule
|
-3.52948
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
-3.2529
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.23877
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.2062
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.20512
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.13047
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-3.10974
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.09203
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.68344
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.56665
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.53585
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.50285
|
|
IMPDH1
|
IMP (inosine 5'-monophosphate) dehydrogenase 1
|
-2.22572
|
|
GABARAPL2
|
GABA(A) receptor-associated protein-like 2
|
-2.17829
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.01748
|
|
ZNF586
|
zinc finger protein 586
|
-2.0115
|
