| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4-chloro-4'-aminodiphenylether 9.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN013_HEPG2_24H:L09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 5.75513 |
| MYLK | myosin light chain kinase | 4.66141 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.30572 |
| ATP11B | ATPase, class VI, type 11B | 4.2711 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 4.21943 |
| STIMATE | STIM activating enhancer | 3.83931 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 3.60414 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.59301 |
| E2F2 | E2F transcription factor 2 | 3.56909 |
| CEP57 | centrosomal protein 57kDa | 3.56614 |
| PIH1D1 | PIH1 domain containing 1 | 3.3969 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 3.34448 |
| RXYLT1 | ribitol xylosyltransferase 1 | 3.25861 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.25248 |
| SOCS2 | suppressor of cytokine signaling 2 | 3.03441 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.0163 |
| CYCS | cytochrome c, somatic | 3.01533 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 2.87923 |
| TBP | TATA box binding protein | 2.58609 |
| TRIB3 | tribbles pseudokinase 3 | 2.57588 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 2.32347 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.32074 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.29727 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.22899 |
| ABHD4 | abhydrolase domain containing 4 | 2.21377 |
| RGS9BP | regulator of G protein signaling 9 binding protein | 2.21224 |
| FZD7 | frizzled class receptor 7 | 2.14843 |
| JADE2 | jade family PHD finger 2 | 2.10446 |
| PRKCH | protein kinase C, eta | 2.04508 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.03189 |
| IL36RN | interleukin 36 receptor antagonist | 2.02711 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -7.66613 |
| ZNF586 | zinc finger protein 586 | -5.4169 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.12355 |
| VAT1 | vesicle amine transport 1 | -4.34915 |
| PLK1 | polo-like kinase 1 | -4.13901 |
| CCNB1 | cyclin B1 | -3.83357 |
| THAP11 | THAP domain containing 11 | -3.79472 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.42138 |
| COG7 | component of oligomeric golgi complex 7 | -3.34063 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.13377 |
| TLR4 | toll-like receptor 4 | -2.84805 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.83068 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.69826 |
| FASTKD5 | FAST kinase domains 5 | -2.69794 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.61329 |
| GNAS | GNAS complex locus | -2.49679 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -2.29646 |
| CDC20 | cell division cycle 20 | -2.26472 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.22799 |
| SNRNP35 | small nuclear ribonucleoprotein 35kDa (U11/U12) | -2.21884 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.15302 |
| ZNF134 | zinc finger protein 134 | -2.12997 |
| PCNA | proliferating cell nuclear antigen | -2.09482 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -2.02648 |
