| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4-chloro-4'-aminodiphenylether 4.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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54 genes differentially expressed following the CRCGN013_HEPG2_24H:L10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 7.2408 |
| JADE2 | jade family PHD finger 2 | 5.60495 |
| MAP7 | microtubule-associated protein 7 | 4.48543 |
| UBQLN2 | ubiquilin 2 | 3.93462 |
| CYCS | cytochrome c, somatic | 3.75785 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.61575 |
| MSRA | methionine sulfoxide reductase A | 3.46361 |
| ABHD4 | abhydrolase domain containing 4 | 3.40049 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 3.17582 |
| TBC1D31 | TBC1 domain family, member 31 | 3.12079 |
| TESK1 | testis-specific kinase 1 | 2.79618 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 2.53653 |
| TRIB3 | tribbles pseudokinase 3 | 2.51082 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.4976 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 2.37179 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 2.25278 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.22958 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 2.22184 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.19489 |
| TPSAB1 | tryptase alpha/beta 1 | 2.18818 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.18793 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.14969 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 2.13769 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.12499 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 2.10076 |
| H2BC12 | H2B clustered histone 12 | 2.07484 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.07418 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.06033 |
| CDK8 | cyclin-dependent kinase 8 | 2.02786 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.31709 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.15406 |
| CCDC86 | coiled-coil domain containing 86 | -4.94059 |
| NUP85 | nucleoporin 85kDa | -4.27779 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.96821 |
| SCAND1 | SCAN domain containing 1 | -3.56651 |
| ZNF586 | zinc finger protein 586 | -3.54837 |
| SLC35F2 | solute carrier family 35, member F2 | -3.50736 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.4225 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.39005 |
| TCERG1 | transcription elongation regulator 1 | -3.34179 |
| HEATR1 | HEAT repeat containing 1 | -3.31581 |
| CCNB1 | cyclin B1 | -3.2333 |
| TCTN1 | tectonic family member 1 | -3.02308 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.00548 |
| TMEM109 | transmembrane protein 109 | -2.78645 |
| PCNA | proliferating cell nuclear antigen | -2.74417 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.68957 |
| GNAS | GNAS complex locus | -2.42193 |
| MRPS7 | mitochondrial ribosomal protein S7 | -2.21701 |
| YME1L1 | YME1-like 1 ATPase | -2.15717 |
| ELAC2 | elaC ribonuclease Z 2 | -2.08426 |
| SUMO4 | small ubiquitin-like modifier 4 | -2.05657 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.03252 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.02446 |
