CRCGN013_HEPG2_24H:L16 Gene Set
Genes
48 genes differentially expressed following the CRCGN013_HEPG2_24H:L16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
7.76818
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
7.30642
|
|
LCN2
|
lipocalin 2
|
6.8124
|
|
SQOR
|
sulfide quinone oxidoreductase
|
5.22985
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.21065
|
|
ANO10
|
anoctamin 10
|
3.63723
|
|
IFIT1
|
interferon-induced protein with tetratricopeptide repeats 1
|
3.50594
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
3.4492
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
3.02579
|
|
MYLK
|
myosin light chain kinase
|
2.96867
|
|
IFIT3
|
interferon-induced protein with tetratricopeptide repeats 3
|
2.74873
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
2.65358
|
|
SIRT3
|
sirtuin 3
|
2.61712
|
|
SFTPB
|
surfactant protein B
|
2.60047
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.55206
|
|
PRR7
|
proline rich 7 (synaptic)
|
2.50695
|
|
RSAD2
|
radical S-adenosyl methionine domain containing 2
|
2.43731
|
|
CCNH
|
cyclin H
|
2.39231
|
|
MX2
|
MX dynamin-like GTPase 2
|
2.34565
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.31936
|
|
OASL
|
2'-5'-oligoadenylate synthetase-like
|
2.25068
|
|
IFI44
|
interferon-induced protein 44
|
2.2344
|
|
OAS2
|
2'-5'-oligoadenylate synthetase 2, 69/71kDa
|
2.1678
|
|
ERMAP
|
erythroblast membrane-associated protein (Scianna blood group)
|
2.15404
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.15317
|
|
ISG15
|
ISG15 ubiquitin-like modifier
|
2.11206
|
|
NMU
|
neuromedin U
|
2.0254
|
|
SAMD9
|
sterile alpha motif domain containing 9
|
2.00751
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.85891
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-7.16079
|
|
TLCD3A
|
TLC domain containing 3A
|
-5.28124
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-5.00555
|
|
TUBB6
|
tubulin, beta 6 class V
|
-4.78985
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-4.62059
|
|
CCNB2
|
cyclin B2
|
-4.2252
|
|
WASHC4
|
WASH complex subunit 4
|
-3.95161
|
|
DNM1L
|
dynamin 1-like
|
-3.63399
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.12908
|
|
MAP7
|
microtubule-associated protein 7
|
-2.89747
|
|
CCNB1
|
cyclin B1
|
-2.69035
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.63828
|
|
CKAP5
|
cytoskeleton associated protein 5
|
-2.47
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.30336
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.19658
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.12028
|
|
PDS5A
|
PDS5 cohesin associated factor A
|
-2.08944
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.07479
|
|
VAT1
|
vesicle amine transport 1
|
-2.03958
|
