| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | emodin 1.25 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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67 genes differentially expressed following the CRCGN013_HEPG2_24H:L17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 7.789 |
| SSBP2 | single-stranded DNA binding protein 2 | 6.39482 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 5.52078 |
| LCN2 | lipocalin 2 | 4.3059 |
| UBQLN2 | ubiquilin 2 | 4.16862 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.97693 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.81053 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.78211 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.70353 |
| INTS3 | integrator complex subunit 3 | 3.61008 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 3.49256 |
| JADE2 | jade family PHD finger 2 | 3.48292 |
| MAP7 | microtubule-associated protein 7 | 3.33592 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.25051 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.20105 |
| EPHB2 | EPH receptor B2 | 3.19048 |
| GATA2 | GATA binding protein 2 | 2.85661 |
| CCNF | cyclin F | 2.79158 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.66483 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.50304 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.43332 |
| CYTH3 | cytohesin 3 | 2.24672 |
| LIPG | lipase, endothelial | 2.20806 |
| PEX12 | peroxisomal biogenesis factor 12 | 2.20066 |
| SYNGR2 | synaptogyrin 2 | 2.19989 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | 2.19412 |
| PLA2G2D | phospholipase A2, group IID | 2.15735 |
| PLA1A | phospholipase A1 member A | 2.13366 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.11118 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.09381 |
| PARD6A | par-6 family cell polarity regulator alpha | 2.07512 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 | 2.07195 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.07036 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 2.02689 |
| TMEM51 | transmembrane protein 51 | 2.02101 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.77952 |
| LDHD | lactate dehydrogenase D | -5.17575 |
| COG7 | component of oligomeric golgi complex 7 | -4.68437 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.65712 |
| ADI1 | acireductone dioxygenase 1 | -4.6475 |
| TRIB3 | tribbles pseudokinase 3 | -4.54322 |
| ZNF586 | zinc finger protein 586 | -4.26759 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -4.19653 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -4.17719 |
| ISOC1 | isochorismatase domain containing 1 | -3.83175 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.72755 |
| RAI14 | retinoic acid induced 14 | -3.42967 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.31996 |
| CCNB2 | cyclin B2 | -3.23986 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.2169 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -3.15285 |
| RNASE7 | ribonuclease, RNase A family, 7 | -2.79029 |
| PCNA | proliferating cell nuclear antigen | -2.75483 |
| CAB39 | calcium binding protein 39 | -2.72476 |
| TES | testin LIM domain protein | -2.72346 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.68994 |
| NMRK1 | nicotinamide riboside kinase 1 | -2.54013 |
| B4GALT3 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 | -2.40393 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.37044 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -2.28998 |
| APEH | acylaminoacyl-peptide hydrolase | -2.20798 |
| IFRD2 | interferon-related developmental regulator 2 | -2.19627 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.12516 |
| IPO4 | importin 4 | -2.11663 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -2.09446 |
| FZD10 | frizzled class receptor 10 | -2.07047 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.04488 |
