| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | emodin 0.62 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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62 genes differentially expressed following the CRCGN013_HEPG2_24H:L18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 7.02286 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.41389 |
| BZW2 | basic leucine zipper and W2 domains 2 | 4.80093 |
| EAPP | E2F-associated phosphoprotein | 4.49281 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.27998 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.95131 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 3.64941 |
| MAP7 | microtubule-associated protein 7 | 3.55772 |
| LCN2 | lipocalin 2 | 3.53518 |
| EPHA3 | EPH receptor A3 | 3.40643 |
| PLS1 | plastin 1 | 3.21529 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.19559 |
| CHMP6 | charged multivesicular body protein 6 | 3.08083 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.04859 |
| MYLK | myosin light chain kinase | 2.96804 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.91822 |
| CBR1 | carbonyl reductase 1 | 2.75776 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 2.71718 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.70846 |
| MELK | maternal embryonic leucine zipper kinase | 2.69568 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.63311 |
| GATA2 | GATA binding protein 2 | 2.5753 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.56198 |
| NOSIP | nitric oxide synthase interacting protein | 2.48639 |
| CHN1 | chimerin 1 | 2.41931 |
| ADAM10 | ADAM metallopeptidase domain 10 | 2.41094 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 2.40716 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.38167 |
| JADE2 | jade family PHD finger 2 | 2.23414 |
| TBC1D31 | TBC1 domain family, member 31 | 2.2178 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.21084 |
| STIMATE | STIM activating enhancer | 2.20966 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.16655 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.13729 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.1139 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.01203 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -7.30564 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.73943 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.68952 |
| ZNF586 | zinc finger protein 586 | -5.28248 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -4.49161 |
| TRIB3 | tribbles pseudokinase 3 | -4.39845 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.30097 |
| LDHD | lactate dehydrogenase D | -4.28549 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.34747 |
| CCNB2 | cyclin B2 | -3.33848 |
| GNAS | GNAS complex locus | -3.3041 |
| VAT1 | vesicle amine transport 1 | -3.23208 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.02186 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.84386 |
| TSPAN4 | tetraspanin 4 | -2.84088 |
| ELAC2 | elaC ribonuclease Z 2 | -2.72965 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.64432 |
| B4GAT1 | beta-1,4-glucuronyltransferase 1 | -2.53908 |
| LRRC41 | leucine rich repeat containing 41 | -2.50805 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.45402 |
| TXNRD1 | thioredoxin reductase 1 | -2.36203 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.35293 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.34274 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.22434 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.15103 |
| NAT10 | N-acetyltransferase 10 (GCN5-related) | -2.11298 |
