CRCGN013_HEPG2_24H:L21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-methyl-1-nitroanthraquinone 5.05 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

572 genes differentially expressed following the CRCGN013_HEPG2_24H:L21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
INPP1 inositol polyphosphate-1-phosphatase 9.19431
LRP10 low density lipoprotein receptor-related protein 10 8.42165
BLCAP bladder cancer associated protein 8.13853
CNPY3 canopy FGF signaling regulator 3 7.90015
TIMP2 TIMP metallopeptidase inhibitor 2 7.44526
MICALL1 MICAL-like 1 7.42236
ABHD4 abhydrolase domain containing 4 7.26229
KIFBP kinesin family binding protein 6.96792
CGRRF1 cell growth regulator with ring finger domain 1 6.82933
CIAO3 cytosolic iron-sulfur assembly component 3 6.62922
DDB2 damage-specific DNA binding protein 2, 48kDa 6.44007
TUBB6 tubulin, beta 6 class V 6.31199
TOMM34 translocase of outer mitochondrial membrane 34 6.03
GPC1 glypican 1 5.87612
CTSL cathepsin L 5.6705
LSR lipolysis stimulated lipoprotein receptor 5.50254
IER3 immediate early response 3 5.27078
CCDC92 coiled-coil domain containing 92 5.25419
DUSP14 dual specificity phosphatase 14 5.23309
ASCC3 activating signal cointegrator 1 complex subunit 3 5.15838
LCN2 lipocalin 2 5.14162
EGR1 early growth response 1 4.97195
ADGRE5 adhesion G protein-coupled receptor E5 4.89189
IL4R interleukin 4 receptor 4.84221
MOK MOK protein kinase 4.82925
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 4.8031
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.74277
MVP major vault protein 4.72258
SMAD3 SMAD family member 3 4.68453
FOSL1 FOS-like antigen 1 4.67223
ADGRG1 adhesion G protein-coupled receptor G1 4.56619
RALB v-ral simian leukemia viral oncogene homolog B 4.37647
PRKCD protein kinase C, delta 4.31994
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 4.1913
ACOT9 acyl-CoA thioesterase 9 4.17399
TERF2IP telomeric repeat binding factor 2, interacting protein 4.16344
CXCR4 chemokine (C-X-C motif) receptor 4 4.08874
TWF2 twinfilin actin binding protein 2 4.05501
TIGAR TP53 induced glycolysis regulatory phosphatase 4.05461
SQOR sulfide quinone oxidoreductase 4.03371
GADD45A growth arrest and DNA-damage-inducible, alpha 3.9434
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.90683
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 3.86384
BAD BCL2-associated agonist of cell death 3.86032
CAB39 calcium binding protein 39 3.83916
KHDC4 KH domain containing 4, pre-mRNA splicing factor 3.83701
MAP7D1 MAP7 domain containing 1 3.79578
PHLDA3 pleckstrin homology-like domain, family A, member 3 3.75621
EPHA2 EPH receptor A2 3.68493
NR1H2 nuclear receptor subfamily 1, group H, member 2 3.67691
CASC3 cancer susceptibility candidate 3 3.65486
JADE2 jade family PHD finger 2 3.63939
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 3.51427
ITGAV integrin, alpha V 3.50427
DHRS7 dehydrogenase/reductase (SDR family) member 7 3.47975
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 3.39801
FOXJ3 forkhead box J3 3.3736
CCL2 chemokine (C-C motif) ligand 2 3.27828
SSBP2 single-stranded DNA binding protein 2 3.25364
MCOLN1 mucolipin 1 3.22926
PSPC1 paraspeckle component 1 3.1964
DNM1L dynamin 1-like 3.19515
CCND3 cyclin D3 3.18784
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 3.15007
CLK3 CDC-like kinase 3 3.13406
FRS2 fibroblast growth factor receptor substrate 2 3.10772
AEN apoptosis enhancing nuclease 3.0922
PRKCQ protein kinase C, theta 3.04692
STX1A syntaxin 1A (brain) 3.0339
ALAS1 5'-aminolevulinate synthase 1 3.02905
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 3.02689
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.00666
H2BC12 H2B clustered histone 12 2.97334
DUSP6 dual specificity phosphatase 6 2.96386
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.96154
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.95128
YJU2B YJU2 splicing factor homolog B 2.92921
TRIB1 tribbles pseudokinase 1 2.91563
KEAP1 kelch-like ECH-associated protein 1 2.91428
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.9008
CSNK1E casein kinase 1, epsilon 2.8909
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.87935
CYCS cytochrome c, somatic 2.87169
LIF leukemia inhibitory factor 2.8622
GIPC1 GIPC PDZ domain containing family, member 1 2.856
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 2.85585
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.84115
ZMAT3 zinc finger, matrin-type 3 2.82868
XPC xeroderma pigmentosum, complementation group C 2.80055
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.79103
ZNF79 zinc finger protein 79 2.78037
PLK3 polo-like kinase 3 2.74829
H2BC21 H2B clustered histone 21 2.71908
DUSP3 dual specificity phosphatase 3 2.71869
ZNF589 zinc finger protein 589 2.65827
SHB Src homology 2 domain containing adaptor protein B 2.6328
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 2.60317
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 2.58971
ZMYM2 zinc finger, MYM-type 2 2.58663
ATG9A autophagy related 9A 2.57904
NUP58 nucleoporin 58 2.56971
CDC50A cell division cycle 50 P4-ATPase accessory subunit A 2.55531
SLC35F2 solute carrier family 35, member F2 2.5426
FAT1 FAT atypical cadherin 1 2.53635
FDXR ferredoxin reductase 2.53492
ULK1 unc-51 like autophagy activating kinase 1 2.52992
FOXD1 forkhead box D1 2.52473
SLC35F6 solute carrier family 35, member F6 2.52257
ADNP activity-dependent neuroprotector homeobox 2.5034
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.50193
DDR1 discoidin domain receptor tyrosine kinase 1 2.50017
GPR87 G protein-coupled receptor 87 2.49332
NGRN neugrin, neurite outgrowth associated 2.49284
ITPKC inositol-trisphosphate 3-kinase C 2.49078
RNF25 ring finger protein 25 2.48595
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.48554
TOR1A torsin family 1, member A (torsin A) 2.4662
LAMB3 laminin, beta 3 2.45944
TEX10 testis expressed 10 2.45814
CTTN cortactin 2.45642
BECN1 beclin 1, autophagy related 2.44634
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.44035
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 2.41686
TRAPPC14 trafficking protein particle complex subunit 14 2.41533
TUT7 terminal uridylyl transferase 7 2.41332
EPHB2 EPH receptor B2 2.41112
GRN granulin 2.40801
FAM168B family with sequence similarity 168, member B 2.39935
MAP3K14 mitogen-activated protein kinase kinase kinase 14 2.39793
IQSEC2 IQ motif and Sec7 domain 2 2.39589
HCFC2 host cell factor C2 2.39165
OFD1 oral-facial-digital syndrome 1 2.3893
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.38584
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 2.37983
H2AC7 H2A clustered histone 7 2.37692
CD9 CD9 molecule 2.37326
RASL12 RAS-like, family 12 2.36937
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 2.36543
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 2.36435
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.36292
DTX2 deltex 2, E3 ubiquitin ligase 2.36241
H2AC6 H2A clustered histone 6 2.36025
PLEC plectin 2.35442
NOP2 NOP2 nucleolar protein 2.35009
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.34694
TRPV4 transient receptor potential cation channel, subfamily V, member 4 2.33626
ECD ecdysoneless homolog (Drosophila) 2.33148
CDKN2A cyclin-dependent kinase inhibitor 2A 2.33136
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.32723
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.32398
TBPL1 TBP-like 1 2.32182
MACF1 microtubule-actin crosslinking factor 1 2.31771
PRSS22 protease, serine, 22 2.30933
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.30541
MICALL2 MICAL-like 2 2.30466
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.29788
SOX4 SRY (sex determining region Y)-box 4 2.29493
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.29232
MAD2L1BP MAD2L1 binding protein 2.29086
EDN1 endothelin 1 2.28643
PRCP prolylcarboxypeptidase (angiotensinase C) 2.26575
TIMP1 TIMP metallopeptidase inhibitor 1 2.26164
SCPEP1 serine carboxypeptidase 1 2.26016
COG7 component of oligomeric golgi complex 7 2.25211
BTG2 BTG family, member 2 2.24561
COL17A1 collagen, type XVII, alpha 1 2.23991
RIN1 Ras and Rab interactor 1 2.23869
POMT1 protein-O-mannosyltransferase 1 2.23585
ELF4 E74-like factor 4 (ets domain transcription factor) 2.23407
DOLK dolichol kinase 2.23326
ZYX zyxin 2.22085
COL4A6 collagen, type IV, alpha 6 2.21991
TRIP12 thyroid hormone receptor interactor 12 2.21421
GATA3 GATA binding protein 3 2.21358
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 2.21106
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.21043
RIOK3 RIO kinase 3 2.20415
ULBP2 UL16 binding protein 2 2.19532
NSUN3 NOP2/Sun domain family, member 3 2.19183
ACOT8 acyl-CoA thioesterase 8 2.18891
ITM2C integral membrane protein 2C 2.18751
ZNF12 zinc finger protein 12 2.18317
TP53BP2 tumor protein p53 binding protein 2 2.18213
DSG2 desmoglein 2 2.18207
DCTN5 dynactin 5 (p25) 2.18178
EIF6 eukaryotic translation initiation factor 6 2.18159
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 2.17593
STOM stomatin 2.17258
EMC7 ER membrane protein complex subunit 7 2.17184
ERCC1 excision repair cross-complementation group 1 2.17101
SNAI1 snail family zinc finger 1 2.16414
NISCH nischarin 2.16043
RUSC2 RUN and SH3 domain containing 2 2.15695
DGKA diacylglycerol kinase, alpha 80kDa 2.15453
SERINC3 serine incorporator 3 2.15401
MPHOSPH8 M-phase phosphoprotein 8 2.15242
TLK2 tousled-like kinase 2 2.14917
RYBP RING1 and YY1 binding protein 2.1439
DSE dermatan sulfate epimerase 2.14218
CD2 CD2 molecule 2.13936
EPN2 epsin 2 2.13925
TXNRD1 thioredoxin reductase 1 2.13867
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.13793
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.1361
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 2.1355
DNM2 dynamin 2 2.13317
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 2.1211
STAMBP STAM binding protein 2.11694
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.11614
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.11476
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 2.11212
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.11047
PROCR protein C receptor, endothelial 2.10375
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 2.09843
BAK1 BCL2-antagonist/killer 1 2.0905
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 2.08587
FURIN furin (paired basic amino acid cleaving enzyme) 2.08563
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.08173
CTPS1 CTP synthase 1 2.07748
EMC3 ER membrane protein complex subunit 3 2.07483
TICAM1 toll-like receptor adaptor molecule 1 2.07117
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 2.06585
MBD1 methyl-CpG binding domain protein 1 2.06144
DAGLA diacylglycerol lipase, alpha 2.06028
CD151 CD151 molecule (Raph blood group) 2.05913
TMPRSS2 transmembrane protease, serine 2 2.05893
WLS wntless Wnt ligand secretion mediator 2.05753
THSD1 thrombospondin, type I, domain containing 1 2.05448
TUBG2 tubulin, gamma 2 2.05428
FNBP4 formin binding protein 4 2.05077
ANKLE2 ankyrin repeat and LEM domain containing 2 2.04308
IL17RA interleukin 17 receptor A 2.0419
KLHL36 kelch-like family member 36 2.03714
S1PR4 sphingosine-1-phosphate receptor 4 2.03418
PNMA3 paraneoplastic Ma antigen 3 2.0289
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 2.02058
COL7A1 collagen, type VII, alpha 1 2.01994
C1QL1 complement component 1, q subcomponent-like 1 2.01875
PPARD peroxisome proliferator-activated receptor delta 2.0148
SUN2 Sad1 and UNC84 domain containing 2 2.01464
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.0144
COL4A5 collagen, type IV, alpha 5 2.00981
BAX BCL2-associated X protein 2.0079
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 2.00738
ATOSB atos homolog B 2.00671
UIMC1 ubiquitin interaction motif containing 1 2.00252
IER2 immediate early response 2 2.00044
EVPL envoplakin 2.00007

decreased expression

Symbol Name Standardized Value
PECR peroxisomal trans-2-enoyl-CoA reductase -7.77192
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -7.68601
FGFR4 fibroblast growth factor receptor 4 -7.60913
PYCR1 pyrroline-5-carboxylate reductase 1 -7.42194
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -6.59396
C2CD5 C2 calcium-dependent domain containing 5 -6.52861
AURKB aurora kinase B -6.30932
PSRC1 proline/serine-rich coiled-coil 1 -6.26015
C5 complement component 5 -6.25643
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -5.99411
ADI1 acireductone dioxygenase 1 -5.82963
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -5.76079
ZW10 zw10 kinetochore protein -5.75653
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -5.70945
STMN1 stathmin 1 -5.62905
NIPSNAP1 nipsnap homolog 1 (C. elegans) -5.61465
COG2 component of oligomeric golgi complex 2 -5.53863
TCTN1 tectonic family member 1 -5.42421
PGM1 phosphoglucomutase 1 -5.38995
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -5.30327
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -5.14061
LBR lamin B receptor -4.90909
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -4.88525
CCNA2 cyclin A2 -4.8047
SOAT2 sterol O-acyltransferase 2 -4.80468
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -4.56298
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.55243
ALDOC aldolase C, fructose-bisphosphate -4.37022
BLMH bleomycin hydrolase -4.35037
ZDHHC6 zinc finger, DHHC-type containing 6 -4.25886
CDC20 cell division cycle 20 -4.24683
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -4.20776
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -4.1096
NUP93 nucleoporin 93kDa -4.08345
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -4.03108
GALE UDP-galactose-4-epimerase -3.98695
MELK maternal embryonic leucine zipper kinase -3.98296
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -3.89054
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.88321
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -3.86587
ADH6 alcohol dehydrogenase 6 (class V) -3.8346
UGDH UDP-glucose 6-dehydrogenase -3.8308
CHEK1 checkpoint kinase 1 -3.82939
MRPL12 mitochondrial ribosomal protein L12 -3.80637
PROS1 protein S (alpha) -3.72958
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -3.67211
LOC124907782 dual specificity protein phosphatase 22 -3.62176
FAM117A family with sequence similarity 117, member A -3.61645
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.59042
CADPS2 Ca++-dependent secretion activator 2 -3.57735
KIF15 kinesin family member 15 -3.55236
HADH hydroxyacyl-CoA dehydrogenase -3.46881
PLK1 polo-like kinase 1 -3.45797
UBE2C ubiquitin-conjugating enzyme E2C -3.45503
DCK deoxycytidine kinase -3.45194
PAH phenylalanine hydroxylase -3.43784
A1CF APOBEC1 complementation factor -3.43729
CDC6 cell division cycle 6 -3.41086
NT5DC2 5'-nucleotidase domain containing 2 -3.41083
LDHD lactate dehydrogenase D -3.40524
TOP2A topoisomerase (DNA) II alpha 170kDa -3.39594
NUCB2 nucleobindin 2 -3.39425
PCCB propionyl CoA carboxylase, beta polypeptide -3.35045
TMEM97 transmembrane protein 97 -3.34557
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.33591
PEG10 paternally expressed 10 -3.30006
TRAP1 TNF receptor-associated protein 1 -3.29706
RNASE4 ribonuclease, RNase A family, 4 -3.27526
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -3.27064
NFIL3 nuclear factor, interleukin 3 regulated -3.27015
ECH1 enoyl CoA hydratase 1, peroxisomal -3.26489
HMGA2 high mobility group AT-hook 2 -3.23363
CCNB1 cyclin B1 -3.22714
KHK ketohexokinase (fructokinase) -3.22231
FBXO5 F-box protein 5 -3.21486
RHOBTB1 Rho-related BTB domain containing 1 -3.1663
KIF14 kinesin family member 14 -3.13864
CDK1 cyclin-dependent kinase 1 -3.13252
PHKB phosphorylase kinase, beta -3.11411
RPIA ribose 5-phosphate isomerase A -3.10735
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.10437
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -3.09346
TLCD3A TLC domain containing 3A -3.07631
DENND2D DENN/MADD domain containing 2D -3.05975
FIRRM FIGNL1 interacting regulator of recombination and mitosis -3.05872
ASGR1 asialoglycoprotein receptor 1 -3.05097
RSU1 Ras suppressor protein 1 -3.03861
UNG uracil-DNA glycosylase -3.00915
PHGDH phosphoglycerate dehydrogenase -2.97387
ETFB electron-transfer-flavoprotein, beta polypeptide -2.95608
MIS18A MIS18 kinetochore protein A -2.9553
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -2.94777
APOM apolipoprotein M -2.93704
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.92298
RFC2 replication factor C (activator 1) 2, 40kDa -2.91636
KLHDC2 kelch domain containing 2 -2.91458
AP1AR adaptor-related protein complex 1 associated regulatory protein -2.89482
SAMM50 SAMM50 sorting and assembly machinery component -2.88812
TRIB3 tribbles pseudokinase 3 -2.88257
APOH apolipoprotein H (beta-2-glycoprotein I) -2.87732
MYL9 myosin, light chain 9, regulatory -2.86737
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -2.85685
TBC1D16 TBC1 domain family, member 16 -2.83869
CDK4 cyclin-dependent kinase 4 -2.83537
ANXA7 annexin A7 -2.83423
BIRC5 baculoviral IAP repeat containing 5 -2.82525
MSRA methionine sulfoxide reductase A -2.82482
CPB2 carboxypeptidase B2 (plasma) -2.82282
SLC30A10 solute carrier family 30, member 10 -2.7952
HEATR1 HEAT repeat containing 1 -2.78885
MEX3D mex-3 RNA binding family member D -2.78619
MYO10 myosin X -2.77326
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.77143
AMBP alpha-1-microglobulin/bikunin precursor -2.77108
SPDEF SAM pointed domain containing ETS transcription factor -2.7573
SPC25 SPC25, NDC80 kinetochore complex component -2.74117
AZGP1 alpha-2-glycoprotein 1, zinc-binding -2.7222
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -2.69527
EXTL2 exostosin-like glycosyltransferase 2 -2.68835
HEBP1 heme binding protein 1 -2.68678
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.68659
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.68612
NR1H4 nuclear receptor subfamily 1, group H, member 4 -2.68363
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -2.67826
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.6625
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.65165
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.64455
MCM10 minichromosome maintenance complex component 10 -2.64378
PLIN2 perilipin 2 -2.64059
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.64044
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -2.63244
EGF epidermal growth factor -2.62159
FAM114A1 family with sequence similarity 114, member A1 -2.61653
CHEK2 checkpoint kinase 2 -2.61235
TEDC2 tubulin epsilon and delta complex 2 -2.60764
GYG2 glycogenin 2 -2.60152
ELP4 elongator acetyltransferase complex subunit 4 -2.60035
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -2.58007
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 -2.57912
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.57186
USP6NL USP6 N-terminal like -2.55578
MSMO1 methylsterol monooxygenase 1 -2.54387
LZTFL1 leucine zipper transcription factor-like 1 -2.54302
ANG angiogenin, ribonuclease, RNase A family, 5 -2.53555
ANO10 anoctamin 10 -2.5317
WDR19 WD repeat domain 19 -2.51955
SORD sorbitol dehydrogenase -2.51643
GPX4 glutathione peroxidase 4 -2.51606
DHCR7 7-dehydrocholesterol reductase -2.50662
PDZD2 PDZ domain containing 2 -2.50641
QDPR quinoid dihydropteridine reductase -2.49635
AMT aminomethyltransferase -2.49537
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.49242
HPD 4-hydroxyphenylpyruvate dioxygenase -2.48888
NRIP1 nuclear receptor interacting protein 1 -2.48699
OAT ornithine aminotransferase -2.48454
GSTM2 glutathione S-transferase mu 2 (muscle) -2.48068
SNRPA small nuclear ribonucleoprotein polypeptide A -2.47912
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.47795
ACO1 aconitase 1, soluble -2.47573
SLC17A2 solute carrier family 17, member 2 -2.46244
GCAT glycine C-acetyltransferase -2.45612
MSH2 mutS homolog 2 -2.44305
LIME1 Lck interacting transmembrane adaptor 1 -2.43994
GFUS GDP-L-fucose synthase -2.4392
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.42704
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.42624
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.41581
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.41481
ERBB3 erb-b2 receptor tyrosine kinase 3 -2.41197
TIMELESS timeless circadian clock -2.40971
PXMP2 peroxisomal membrane protein 2, 22kDa -2.40603
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.40117
HMG20B high mobility group 20B -2.39477
PFKL phosphofructokinase, liver -2.3945
NUBPL nucleotide binding protein-like -2.37961
SEPTIN11 septin 11 -2.37608
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.37058
PYGL phosphorylase, glycogen, liver -2.36954
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.36682
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -2.36472
RNF144A ring finger protein 144A -2.36349
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -2.36217
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 -2.36205
GIPC2 GIPC PDZ domain containing family, member 2 -2.36169
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -2.3526
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.34703
DHRS4 dehydrogenase/reductase (SDR family) member 4 -2.34253
DENND10 DENN domain containing 10 -2.34194
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -2.33808
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -2.32656
PWP1 PWP1 homolog (S. cerevisiae) -2.32568
GLOD4 glyoxalase domain containing 4 -2.32093
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -2.31363
GNAS GNAS complex locus -2.31326
GMDS GDP-mannose 4,6-dehydratase -2.30954
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.3047
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -2.30289
HYDIN HYDIN, axonemal central pair apparatus protein -2.29857
CENPX centromere protein X -2.29654
AHSG alpha-2-HS-glycoprotein -2.29563
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -2.29406
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.29187
NUP85 nucleoporin 85kDa -2.2914
CYP3A7-CYP3A51P CYP3A7-CYP3A51P readthrough -2.28869
IFT81 intraflagellar transport 81 -2.28674
AGMAT agmatine ureohydrolase (agmatinase) -2.28102
DERA deoxyribose-phosphate aldolase (putative) -2.2789
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 -2.27796
APOC3 apolipoprotein C-III -2.27694
ICAM3 intercellular adhesion molecule 3 -2.26892
TRAPPC4 trafficking protein particle complex 4 -2.26566
EXPH5 exophilin 5 -2.258
CFI complement factor I -2.25326
OXCT1 3-oxoacid CoA transferase 1 -2.25038
CENPS-CORT CENPS-CORT readthrough -2.24931
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.24768
AKR1D1 aldo-keto reductase family 1, member D1 -2.24509
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -2.23867
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.23738
DNAI7 dynein axonemal intermediate chain 7 -2.23487
FIBP fibroblast growth factor (acidic) intracellular binding protein -2.23329
ACOX2 acyl-CoA oxidase 2, branched chain -2.22772
MARCKSL1 MARCKS-like 1 -2.2236
LMNB1 lamin B1 -2.22257
USP1 ubiquitin specific peptidase 1 -2.21669
ACADSB acyl-CoA dehydrogenase, short/branched chain -2.21637
ATP7B ATPase, Cu++ transporting, beta polypeptide -2.21555
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.21441
UXT ubiquitously-expressed, prefoldin-like chaperone -2.21153
TRIP13 thyroid hormone receptor interactor 13 -2.20732
NANS N-acetylneuraminic acid synthase -2.20645
GLYAT glycine-N-acyltransferase -2.20427
PIPOX pipecolic acid oxidase -2.20387
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.19697
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.19486
ENOPH1 enolase-phosphatase 1 -2.19485
SDAD1 SDA1 domain containing 1 -2.19188
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.19068
HBE1 hemoglobin, epsilon 1 -2.18999
TBC1D8B TBC1 domain family, member 8B (with GRAM domain) -2.18115
ACSM3 acyl-CoA synthetase medium-chain family member 3 -2.17661
FGA fibrinogen alpha chain -2.1709
BRD7 bromodomain containing 7 -2.16978
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -2.16549
PM20D1 peptidase M20 domain containing 1 -2.15699
SCD stearoyl-CoA desaturase (delta-9-desaturase) -2.15486
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 -2.15402
OCEL1 occludin/ELL domain containing 1 -2.14955
IQGAP2 IQ motif containing GTPase activating protein 2 -2.14923
PLS1 plastin 1 -2.14868
TTC27 tetratricopeptide repeat domain 27 -2.14123
MB myoglobin -2.13845
PIGR polymeric immunoglobulin receptor -2.1356
PANK3 pantothenate kinase 3 -2.1327
SCGB1D1 secretoglobin, family 1D, member 1 -2.12887
CFHR5 complement factor H-related 5 -2.12616
INSIG1 insulin induced gene 1 -2.12576
UBP1 upstream binding protein 1 (LBP-1a) -2.12473
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -2.12207
JRKL JRK-like -2.11758
CDT1 chromatin licensing and DNA replication factor 1 -2.11727
XYLT1 xylosyltransferase I -2.11689
MBL2 mannose-binding lectin (protein C) 2, soluble -2.11637
MSH6 mutS homolog 6 -2.10662
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.10512
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -2.10489
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 -2.10299
SQLE squalene epoxidase -2.10283
CEP83 centrosomal protein 83kDa -2.0997
ADD3 adducin 3 (gamma) -2.09262
GOLPH3L golgi phosphoprotein 3-like -2.09256
FGF9 fibroblast growth factor 9 -2.08866
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.08832
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -2.08612
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -2.08583
PKLR pyruvate kinase, liver and RBC -2.08561
NME5 NME/NM23 family member 5 -2.08337
WDR18 WD repeat domain 18 -2.08108
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.07952
RNF130 ring finger protein 130 -2.07781
PFAS phosphoribosylformylglycinamidine synthase -2.07484
IFI30 interferon, gamma-inducible protein 30 -2.07249
DAZAP1 DAZ associated protein 1 -2.07095
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) -2.0703
CBLN1 cerebellin 1 precursor -2.07028
PEG3 paternally expressed 3 -2.06833
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -2.06474
ZNF518A zinc finger protein 518A -2.06426
ATL2 atlastin GTPase 2 -2.06318
AGXT alanine-glyoxylate aminotransferase -2.06035
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.05998
DHCR24 24-dehydrocholesterol reductase -2.05891
AK4 adenylate kinase 4 -2.05729
PDIA5 protein disulfide isomerase family A, member 5 -2.05247
ZNF552 zinc finger protein 552 -2.04939
PDGFD platelet derived growth factor D -2.04823
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -2.04575
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -2.04516
GCA grancalcin, EF-hand calcium binding protein -2.04512
WASF1 WAS protein family, member 1 -2.04436
GAS2 growth arrest-specific 2 -2.04228
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.03918
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -2.03873
PLSCR4 phospholipid scramblase 4 -2.03681
FBF1 Fas (TNFRSF6) binding factor 1 -2.03426
SDF2L1 stromal cell-derived factor 2-like 1 -2.03211
PRUNE1 prune exopolyphosphatase 1 -2.02446
CFHR2 complement factor H-related 2 -2.02405
DUT deoxyuridine triphosphatase -2.02397
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -2.02154
NRTN neurturin -2.01863
OTC ornithine carbamoyltransferase -2.01824
MTTP microsomal triglyceride transfer protein -2.01675
LIPC lipase, hepatic -2.01652
PRODH2 proline dehydrogenase (oxidase) 2 -2.01467
RABL3 RAB, member of RAS oncogene family-like 3 -2.01389
DDAH1 dimethylarginine dimethylaminohydrolase 1 -2.00874
CXCL6 chemokine (C-X-C motif) ligand 6 -2.00777
NQO2 NAD(P)H dehydrogenase, quinone 2 -2.00626
TRAPPC3 trafficking protein particle complex 3 -2.00438
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -2.00155
TMEM176A transmembrane protein 176A -2.00123