CRCGN013_HEPG2_24H:M03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isopropanol 10.6 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

39 genes differentially expressed following the CRCGN013_HEPG2_24H:M03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LCN2 lipocalin 2 6.2151
GPER1 G protein-coupled estrogen receptor 1 5.78017
MOK MOK protein kinase 4.82751
RPP38 ribonuclease P/MRP 38kDa subunit 4.4026
SNAP25 synaptosomal-associated protein, 25kDa 4.20175
CARMIL1 capping protein regulator and myosin 1 linker 1 4.03723
SPTAN1 spectrin, alpha, non-erythrocytic 1 3.92157
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.91537
MYLK myosin light chain kinase 3.86471
HOXA10 homeobox A10 3.21328
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 3.11062
PTK2 protein tyrosine kinase 2 2.78086
PRR15L proline rich 15-like 2.72939
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.56583
HLA-DMA major histocompatibility complex, class II, DM alpha 2.42766
CNPY3 canopy FGF signaling regulator 3 2.39444
HLA-DRA major histocompatibility complex, class II, DR alpha 2.14879
JADE2 jade family PHD finger 2 2.13315
KIF20A kinesin family member 20A 2.07401
NPDC1 neural proliferation, differentiation and control, 1 2.00435
KLHDC3 kelch domain containing 3 2.00234

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.49353
PCNA proliferating cell nuclear antigen -4.61029
ADI1 acireductone dioxygenase 1 -4.60073
UBE3C ubiquitin protein ligase E3C -4.47078
LDHD lactate dehydrogenase D -4.38677
MAP7 microtubule-associated protein 7 -4.13453
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.88812
TLCD3A TLC domain containing 3A -3.68144
MAPK13 mitogen-activated protein kinase 13 -3.5237
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.40679
AZGP1 alpha-2-glycoprotein 1, zinc-binding -2.97995
CCNB1 cyclin B1 -2.80192
TXNDC9 thioredoxin domain containing 9 -2.7235
GLOD4 glyoxalase domain containing 4 -2.64112
BLCAP bladder cancer associated protein -2.49746
FBXL12 F-box and leucine-rich repeat protein 12 -2.3579
USP6NL USP6 N-terminal like -2.19946
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -2.14984