| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | isopropanol 2.65 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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63 genes differentially expressed following the CRCGN013_HEPG2_24H:M05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STIMATE | STIM activating enhancer | 7.88726 |
| LCN2 | lipocalin 2 | 7.74028 |
| RPL39L | ribosomal protein L39-like | 5.6906 |
| MYLK | myosin light chain kinase | 5.29403 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 5.02006 |
| ADRB2 | adrenoceptor beta 2, surface | 4.98952 |
| CBR3 | carbonyl reductase 3 | 4.96608 |
| KLHL21 | kelch-like family member 21 | 4.92126 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.89064 |
| MOK | MOK protein kinase | 4.87418 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.77899 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 4.25368 |
| CHN1 | chimerin 1 | 3.90417 |
| GPATCH8 | G patch domain containing 8 | 3.84782 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 3.52555 |
| KDM5A | lysine (K)-specific demethylase 5A | 3.50045 |
| VGLL4 | vestigial-like family member 4 | 3.47919 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.30701 |
| MAN2B2 | mannosidase, alpha, class 2B, member 2 | 2.73143 |
| STXBP1 | syntaxin binding protein 1 | 2.6838 |
| NOSIP | nitric oxide synthase interacting protein | 2.58518 |
| LAGE3 | L antigen family, member 3 | 2.52954 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.47659 |
| WASF3 | WAS protein family, member 3 | 2.46852 |
| TLR4 | toll-like receptor 4 | 2.40803 |
| BCLAF1 | BCL2-associated transcription factor 1 | 2.34696 |
| WDR11 | WD repeat domain 11 | 2.22571 |
| CD4 | CD4 molecule | 2.20626 |
| NUDT19 | nudix (nucleoside diphosphate linked moiety X)-type motif 19 | 2.19491 |
| CSK | c-src tyrosine kinase | 2.15467 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | 2.15163 |
| TP53RK | TP53 regulating kinase | 2.10049 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 2.07853 |
| UBFD1 | ubiquitin family domain containing 1 | 2.06261 |
| CILK1 | ciliogenesis associated kinase 1 | 2.05042 |
| EGF | epidermal growth factor | 2.04176 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 2.02115 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 2.00494 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDC20 | cell division cycle 20 | -6.46079 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.68601 |
| RPN1 | ribophorin I | -5.49476 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.25513 |
| LDHD | lactate dehydrogenase D | -5.18083 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -5.13668 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.6097 |
| CCNB2 | cyclin B2 | -4.32408 |
| PCNA | proliferating cell nuclear antigen | -3.17019 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.09859 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.63649 |
| RPS5 | ribosomal protein S5 | -2.5957 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.56565 |
| SPAG4 | sperm associated antigen 4 | -2.376 |
| COPG1 | coatomer protein complex, subunit gamma 1 | -2.3346 |
| PRPF4 | pre-mRNA processing factor 4 | -2.32812 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.16477 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.15654 |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) | -2.13959 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 | -2.10728 |
| PRAF2 | PRA1 domain family, member 2 | -2.05836 |
| RGS2 | regulator of G-protein signaling 2 | -2.02687 |
| CCNB1 | cyclin B1 | -2.01608 |
| CORO1C | coronin, actin binding protein, 1C | -2.00293 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | -2.00276 |
