CRCGN013_HEPG2_24H:M08 Gene Set
Genes
55 genes differentially expressed following the CRCGN013_HEPG2_24H:M08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.61799
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.25305
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
4.20722
|
|
EPHB2
|
EPH receptor B2
|
4.14169
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.96486
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.68938
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.60389
|
|
TBP
|
TATA box binding protein
|
3.42829
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.40065
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.33003
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
3.18429
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.99279
|
|
PKN1
|
protein kinase N1
|
2.78488
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.77507
|
|
LCN2
|
lipocalin 2
|
2.75119
|
|
STXBP2
|
syntaxin binding protein 2
|
2.61856
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.54977
|
|
BCL2L10
|
BCL2-like 10 (apoptosis facilitator)
|
2.1397
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.10329
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.08726
|
|
RPAP3
|
RNA polymerase II associated protein 3
|
2.08573
|
|
CEP57
|
centrosomal protein 57kDa
|
2.07169
|
|
CCNF
|
cyclin F
|
2.04782
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.00477
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLCD3A
|
TLC domain containing 3A
|
-6.80913
|
|
GNAS
|
GNAS complex locus
|
-6.36146
|
|
LDHD
|
lactate dehydrogenase D
|
-5.88837
|
|
CCNB2
|
cyclin B2
|
-5.35293
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.85594
|
|
CD320
|
CD320 molecule
|
-4.46087
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.28876
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.24518
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.18608
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.14963
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-4.1003
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.90015
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.88583
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-3.84922
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.79729
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.75161
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.68537
|
|
CCNB1
|
cyclin B1
|
-3.34465
|
|
RNF167
|
ring finger protein 167
|
-3.11767
|
|
ZNF586
|
zinc finger protein 586
|
-2.84459
|
|
MMP8
|
matrix metallopeptidase 8
|
-2.33198
|
|
ITM2B
|
integral membrane protein 2B
|
-2.25894
|
|
ZIC1
|
Zic family member 1
|
-2.24085
|
|
CEACAM8
|
carcinoembryonic antigen-related cell adhesion molecule 8
|
-2.19831
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.19231
|
|
PDCD5
|
programmed cell death 5
|
-2.19198
|
|
TBCB
|
tubulin folding cofactor B
|
-2.15589
|
|
LTF
|
lactotransferrin
|
-2.13514
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
-2.12059
|
|
TUBB4A
|
tubulin, beta 4A class IVa
|
-2.1144
|
|
COX6B1
|
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
|
-2.03494
|
