CRCGN013_HEPG2_24H:M11 Gene Set
Genes
45 genes differentially expressed following the CRCGN013_HEPG2_24H:M11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
10.0
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
5.34548
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.88694
|
|
E2F2
|
E2F transcription factor 2
|
4.22088
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.9851
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.78118
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.60183
|
|
H2BC12
|
H2B clustered histone 12
|
2.97039
|
|
PCDHB11
|
protocadherin beta 11
|
2.78407
|
|
IGHMBP2
|
immunoglobulin mu binding protein 2
|
2.53204
|
|
CCNF
|
cyclin F
|
2.44712
|
|
SNX7
|
sorting nexin 7
|
2.40955
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.28708
|
|
CEP57
|
centrosomal protein 57kDa
|
2.26449
|
|
SMAD3
|
SMAD family member 3
|
2.17948
|
|
CYCS
|
cytochrome c, somatic
|
2.16103
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.13025
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.11645
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.09004
|
|
SLC4A3
|
solute carrier family 4 (anion exchanger), member 3
|
2.07521
|
|
ZNF589
|
zinc finger protein 589
|
2.03909
|
|
CDC123
|
cell division cycle 123
|
2.03789
|
|
MPC2
|
mitochondrial pyruvate carrier 2
|
2.01611
|
|
RBP4
|
retinol binding protein 4, plasma
|
2.01142
|
|
TFPT
|
TCF3 (E2A) fusion partner (in childhood Leukemia)
|
2.00698
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.38736
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-5.07294
|
|
CDC20
|
cell division cycle 20
|
-4.87175
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.83753
|
|
THAP11
|
THAP domain containing 11
|
-4.72715
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.69075
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.88921
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-3.57062
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.41245
|
|
HMG20B
|
high mobility group 20B
|
-3.34954
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-3.34673
|
|
MAP7
|
microtubule-associated protein 7
|
-3.26933
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.88015
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.86523
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.79295
|
|
CTSD
|
cathepsin D
|
-2.69475
|
|
EGF
|
epidermal growth factor
|
-2.59585
|
|
SENP6
|
SUMO1/sentrin specific peptidase 6
|
-2.43676
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.33236
|
|
CLDN1
|
claudin 1
|
-2.00828
|
