| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dipropylene glycol 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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67 genes differentially expressed following the CRCGN013_HEPG2_24H:M12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 6.86503 |
| NOTCH1 | notch 1 | 6.65943 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 6.6509 |
| LCN2 | lipocalin 2 | 6.2253 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.63717 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 4.45937 |
| STK10 | serine/threonine kinase 10 | 3.61 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.55377 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.53905 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.47317 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.44867 |
| E2F2 | E2F transcription factor 2 | 3.35637 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 3.3271 |
| CHMP6 | charged multivesicular body protein 6 | 3.28483 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.16903 |
| TATDN2 | TatD DNase domain containing 2 | 3.03787 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.0213 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.98177 |
| NOSIP | nitric oxide synthase interacting protein | 2.70543 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 2.68393 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.58053 |
| CHN1 | chimerin 1 | 2.49977 |
| MICALL1 | MICAL-like 1 | 2.45137 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.38757 |
| EPHB2 | EPH receptor B2 | 2.38658 |
| CDK19 | cyclin-dependent kinase 19 | 2.29386 |
| LOC122526780 | uncharacterized LOC122526780 | 2.27647 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 2.2334 |
| PIH1D1 | PIH1 domain containing 1 | 2.15867 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.12063 |
| GATA2 | GATA binding protein 2 | 2.10952 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.08647 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.0642 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) | 2.0579 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.66667 |
| PCNA | proliferating cell nuclear antigen | -5.33837 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -5.32377 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -5.2212 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.46463 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -3.33333 |
| AARS1 | alanyl-tRNA synthetase 1 | -3.3199 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.29597 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.2829 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.2795 |
| DNM1L | dynamin 1-like | -3.1534 |
| LDHD | lactate dehydrogenase D | -3.00593 |
| DCTD | dCMP deaminase | -2.92849 |
| TCERG1 | transcription elongation regulator 1 | -2.7349 |
| TLCD3A | TLC domain containing 3A | -2.71407 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.6975 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.56792 |
| TLR4 | toll-like receptor 4 | -2.53983 |
| THAP11 | THAP domain containing 11 | -2.51773 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -2.51333 |
| NUP85 | nucleoporin 85kDa | -2.33063 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.2965 |
| GNAS | GNAS complex locus | -2.28889 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.27873 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.26143 |
| ZNF586 | zinc finger protein 586 | -2.25427 |
| TES | testin LIM domain protein | -2.14127 |
| CDR2L | cerebellar degeneration-related protein 2-like | -2.14 |
| EGF | epidermal growth factor | -2.13713 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.10243 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.10233 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | -2.07453 |
| ARRB2 | arrestin, beta 2 | -2.06467 |
