CRCGN013_HEPG2_24H:M14 Gene Set
Genes
48 genes differentially expressed following the CRCGN013_HEPG2_24H:M14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
6.26018
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
5.68116
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.39832
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
4.19662
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.82432
|
|
STAP2
|
signal transducing adaptor family member 2
|
3.71539
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.6015
|
|
STK10
|
serine/threonine kinase 10
|
3.50389
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.50338
|
|
UBQLN2
|
ubiquilin 2
|
3.32335
|
|
MYLK
|
myosin light chain kinase
|
3.18016
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.02486
|
|
TBP
|
TATA box binding protein
|
2.53368
|
|
RAB4A
|
RAB4A, member RAS oncogene family
|
2.47243
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
2.42544
|
|
SMAD3
|
SMAD family member 3
|
2.29228
|
|
LCN2
|
lipocalin 2
|
2.26292
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.17673
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.15313
|
|
PFKL
|
phosphofructokinase, liver
|
2.11197
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
2.09417
|
|
PCDHB11
|
protocadherin beta 11
|
2.06933
|
|
AAAS
|
achalasia, adrenocortical insufficiency, alacrimia
|
2.0441
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.1017
|
|
GNAS
|
GNAS complex locus
|
-4.81039
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-4.44534
|
|
LDHD
|
lactate dehydrogenase D
|
-4.35926
|
|
RPN1
|
ribophorin I
|
-4.16073
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.95521
|
|
VAT1
|
vesicle amine transport 1
|
-3.91452
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.88053
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.83364
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.70669
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.55911
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.37289
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.32316
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.29848
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.73154
|
|
CTSD
|
cathepsin D
|
-2.50678
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-2.49187
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.33831
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.30973
|
|
ILK
|
integrin-linked kinase
|
-2.3088
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.27279
|
|
GDF15
|
growth differentiation factor 15
|
-2.18817
|
|
CCNB1
|
cyclin B1
|
-2.12343
|
|
METTL22
|
methyltransferase like 22
|
-2.06102
|
|
PSMC1
|
proteasome (prosome, macropain) 26S subunit, ATPase, 1
|
-2.02188
|
