CRCGN013_HEPG2_24H:M15 Gene Set
Genes
39 genes differentially expressed following the CRCGN013_HEPG2_24H:M15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
5.95463
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.83896
|
|
RAB21
|
RAB21, member RAS oncogene family
|
3.71495
|
|
GNAI2
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
|
3.6555
|
|
CYCS
|
cytochrome c, somatic
|
3.3261
|
|
E2F2
|
E2F transcription factor 2
|
3.27307
|
|
PLS1
|
plastin 1
|
3.13764
|
|
UBQLN2
|
ubiquilin 2
|
3.08382
|
|
PHKG2
|
phosphorylase kinase, gamma 2 (testis)
|
3.07282
|
|
STK10
|
serine/threonine kinase 10
|
3.0416
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.95381
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.77648
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.73216
|
|
CCNA1
|
cyclin A1
|
2.56676
|
|
EGF
|
epidermal growth factor
|
2.56498
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.50014
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.47873
|
|
CEP57
|
centrosomal protein 57kDa
|
2.47609
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.37357
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.35968
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
2.10087
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.09804
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
2.08574
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-4.61565
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.73926
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.53664
|
|
CD320
|
CD320 molecule
|
-3.4735
|
|
ZNF586
|
zinc finger protein 586
|
-3.20582
|
|
LDHD
|
lactate dehydrogenase D
|
-3.09125
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.0436
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.99789
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.84245
|
|
TRAPPC3
|
trafficking protein particle complex 3
|
-2.83968
|
|
GNAS
|
GNAS complex locus
|
-2.64563
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.3756
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.34346
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.29432
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.19493
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.0427
|
