| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sodium (e)-4-hydroxy-3-((4-sulfonatonaphthalen-1-yl)diazenyl)naphthalene-1-sulfonate 2.74 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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71 genes differentially expressed following the CRCGN013_HEPG2_24H:M16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 6.02581 |
| LCN2 | lipocalin 2 | 4.89105 |
| NOTCH1 | notch 1 | 4.5693 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.17759 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.11104 |
| EPHB2 | EPH receptor B2 | 4.02036 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 3.89554 |
| CYCS | cytochrome c, somatic | 3.79544 |
| VGLL4 | vestigial-like family member 4 | 3.46982 |
| EPN2 | epsin 2 | 3.35023 |
| NOSIP | nitric oxide synthase interacting protein | 3.32071 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.15315 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.09366 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.88681 |
| ATP11B | ATPase, class VI, type 11B | 2.87112 |
| GPATCH8 | G patch domain containing 8 | 2.68 |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) | 2.65003 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.64985 |
| SAR1B | secretion associated, Ras related GTPase 1B | 2.6332 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.62148 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.61667 |
| KIF20A | kinesin family member 20A | 2.37032 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.36906 |
| MATN4 | matrilin 4 | 2.36273 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.34053 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.33686 |
| RHOT1 | ras homolog family member T1 | 2.28916 |
| CCNF | cyclin F | 2.21857 |
| LOC122526780 | uncharacterized LOC122526780 | 2.21742 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 2.20351 |
| C1QL1 | complement component 1, q subcomponent-like 1 | 2.14682 |
| TPSG1 | tryptase gamma 1 | 2.13462 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 2.12001 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 2.10282 |
| ADGRB1 | adhesion G protein-coupled receptor B1 | 2.10191 |
| ZNF589 | zinc finger protein 589 | 2.07556 |
| CDX1 | caudal type homeobox 1 | 2.07355 |
| GPA33 | glycoprotein A33 (transmembrane) | 2.07305 |
| COL9A2 | collagen, type IX, alpha 2 | 2.04242 |
| KLHL9 | kelch-like family member 9 | 2.01114 |
| SCRG1 | stimulator of chondrogenesis 1 | 2.00033 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.75451 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.3659 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.34714 |
| MAP7 | microtubule-associated protein 7 | -4.23533 |
| LDHD | lactate dehydrogenase D | -4.01531 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.01037 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.96964 |
| LAP3 | leucine aminopeptidase 3 | -3.95822 |
| GDF15 | growth differentiation factor 15 | -3.79819 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.75323 |
| EGF | epidermal growth factor | -3.66085 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.52374 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.49503 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.19526 |
| COG2 | component of oligomeric golgi complex 2 | -3.13818 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.02279 |
| CCNB2 | cyclin B2 | -2.88044 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.85345 |
| TCERG1 | transcription elongation regulator 1 | -2.75435 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.72483 |
| NUP62CL | nucleoporin 62kDa C-terminal like | -2.55551 |
| WASHC4 | WASH complex subunit 4 | -2.44933 |
| VAT1 | vesicle amine transport 1 | -2.34594 |
| GNAS | GNAS complex locus | -2.33173 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | -2.29655 |
| QRICH1 | glutamine-rich 1 | -2.17811 |
| MID1IP1 | MID1 interacting protein 1 | -2.1033 |
| HMG20B | high mobility group 20B | -2.08381 |
| EXT1 | exostosin glycosyltransferase 1 | -2.06817 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.05999 |
