CRCGN013_HEPG2_24H:M17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sodium (e)-4-hydroxy-3-((4-sulfonatonaphthalen-1-yl)diazenyl)naphthalene-1-sulfonate 1.37 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN013_HEPG2_24H:M17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CHN1 chimerin 1 7.22244
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.58421
PPARG peroxisome proliferator-activated receptor gamma 4.44451
SQOR sulfide quinone oxidoreductase 4.44081
PEX11A peroxisomal biogenesis factor 11 alpha 4.2543
CIAO3 cytosolic iron-sulfur assembly component 3 4.18412
CHMP6 charged multivesicular body protein 6 4.12751
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 3.91473
ADAT1 adenosine deaminase, tRNA-specific 1 3.20168
RXYLT1 ribitol xylosyltransferase 1 3.02907
BPHL biphenyl hydrolase-like (serine hydrolase) 2.93047
VGLL4 vestigial-like family member 4 2.63224
PRR15L proline rich 15-like 2.54415
ZNF136 zinc finger protein 136 2.28903
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.16871
BAX BCL2-associated X protein 2.16811
ETFA electron-transfer-flavoprotein, alpha polypeptide 2.14953
UBL5 ubiquitin-like 5 2.13057
LYZ lysozyme 2.07507
GPER1 G protein-coupled estrogen receptor 1 2.05751
NOSIP nitric oxide synthase interacting protein 2.02272

decreased expression

Symbol Name Standardized Value
CCNB2 cyclin B2 -6.96396
OXA1L oxidase (cytochrome c) assembly 1-like -4.99028
LDHD lactate dehydrogenase D -4.65519
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.30609
MAPK13 mitogen-activated protein kinase 13 -3.98267
TLCD3A TLC domain containing 3A -3.86167
FAIM Fas apoptotic inhibitory molecule -3.25639
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.10963
TOR1A torsin family 1, member A (torsin A) -2.95365
BLCAP bladder cancer associated protein -2.87157
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.84596
HLA-DMA major histocompatibility complex, class II, DM alpha -2.15309
SYNGAP1 synaptic Ras GTPase activating protein 1 -2.14495
RNF167 ring finger protein 167 -2.08262