CRCGN013_HEPG2_24H:M19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description diisononyl phthalate 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

38 genes differentially expressed following the CRCGN013_HEPG2_24H:M19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 7.59105
CHN1 chimerin 1 6.0387
UBQLN2 ubiquilin 2 5.14605
ANO1 anoctamin 1, calcium activated chloride channel 4.90532
LCN2 lipocalin 2 4.90511
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.98076
KCNK1 potassium channel, two pore domain subfamily K, member 1 3.62371
SNAP25 synaptosomal-associated protein, 25kDa 3.53674
EVL Enah/Vasp-like 3.30314
TIAM1 T-cell lymphoma invasion and metastasis 1 3.12199
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 3.10676
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.62656
LOC122526780 uncharacterized LOC122526780 2.62283
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.3912
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.38502
GPATCH8 G patch domain containing 8 2.33896
COL11A1 collagen, type XI, alpha 1 2.32412
TBXA2R thromboxane A2 receptor 2.26679
ZNF589 zinc finger protein 589 2.25081
CCNH cyclin H 2.13528
KLHL21 kelch-like family member 21 2.11429
CD40 CD40 molecule, TNF receptor superfamily member 5 2.00976

decreased expression

Symbol Name Standardized Value
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -7.08524
TUBB6 tubulin, beta 6 class V -4.99623
DNM1L dynamin 1-like -4.70891
LDHD lactate dehydrogenase D -4.58501
MAP7 microtubule-associated protein 7 -4.20511
CCNB2 cyclin B2 -3.58546
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.583
UGDH UDP-glucose 6-dehydrogenase -3.21504
ADI1 acireductone dioxygenase 1 -3.03009
KDM3A lysine (K)-specific demethylase 3A -2.46127
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.42091
TLR4 toll-like receptor 4 -2.35756
VAT1 vesicle amine transport 1 -2.26836
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.21656
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -2.11664
FGFR4 fibroblast growth factor receptor 4 -2.0823