CRCGN013_HEPG2_24H:M20 Gene Set
Genes
43 genes differentially expressed following the CRCGN013_HEPG2_24H:M20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
8.16033
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.59708
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.23914
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.94005
|
|
GNAI2
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
|
3.86646
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
3.85595
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.72961
|
|
HDGFL3
|
HDGF like 3
|
3.46397
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.40069
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.34931
|
|
ZNF589
|
zinc finger protein 589
|
3.16476
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.10973
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.98573
|
|
EPN2
|
epsin 2
|
2.71309
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.6985
|
|
HOOK2
|
hook microtubule-tethering protein 2
|
2.57245
|
|
KIF5C
|
kinesin family member 5C
|
2.56405
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.48656
|
|
STXBP2
|
syntaxin binding protein 2
|
2.35949
|
|
LAGE3
|
L antigen family, member 3
|
2.2705
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.19697
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.14621
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.09244
|
|
PRR15L
|
proline rich 15-like
|
2.0824
|
|
SGCB
|
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
|
2.07875
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.01429
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-4.23168
|
|
ALAS1
|
5'-aminolevulinate synthase 1
|
-4.19786
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-3.8532
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.81252
|
|
LDHD
|
lactate dehydrogenase D
|
-3.79491
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.76084
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.7334
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.7154
|
|
HMG20B
|
high mobility group 20B
|
-3.32524
|
|
CCNB2
|
cyclin B2
|
-3.25379
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.14022
|
|
GNAS
|
GNAS complex locus
|
-2.7385
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.62352
|
|
RBM34
|
RNA binding motif protein 34
|
-2.34253
|
|
SESN1
|
sestrin 1
|
-2.32354
|
|
PGM1
|
phosphoglucomutase 1
|
-2.12219
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.03198
|
