CRCGN013_HEPG2_24H:M21 Gene Set
Genes
43 genes differentially expressed following the CRCGN013_HEPG2_24H:M21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GPER1
|
G protein-coupled estrogen receptor 1
|
6.15781
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.82174
|
|
CYCS
|
cytochrome c, somatic
|
4.62511
|
|
MSRA
|
methionine sulfoxide reductase A
|
4.13793
|
|
LCN2
|
lipocalin 2
|
3.89668
|
|
NOTCH1
|
notch 1
|
3.54029
|
|
CHN1
|
chimerin 1
|
3.51439
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.1297
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
2.88041
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.6721
|
|
PRR15L
|
proline rich 15-like
|
2.59994
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.44745
|
|
PRKCH
|
protein kinase C, eta
|
2.3051
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.22986
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.12068
|
|
CETN3
|
centrin, EF-hand protein, 3
|
2.01781
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.55293
|
|
CDC20
|
cell division cycle 20
|
-6.10332
|
|
CCNB2
|
cyclin B2
|
-3.90481
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-3.76319
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.75178
|
|
VAT1
|
vesicle amine transport 1
|
-3.72556
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.72528
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.61841
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.5928
|
|
PLK1
|
polo-like kinase 1
|
-3.52939
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.45718
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.17085
|
|
RGS2
|
regulator of G-protein signaling 2
|
-3.13573
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.06735
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.85296
|
|
TLR4
|
toll-like receptor 4
|
-2.73955
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.56138
|
|
CCNB1
|
cyclin B1
|
-2.45362
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.42371
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.40491
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.26271
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.20592
|
|
GNAS
|
GNAS complex locus
|
-2.18175
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.17239
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.07138
|
|
SMAP1
|
small ArfGAP 1
|
-2.05441
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.05321
|
