CRCGN013_HEPG2_24H:M22 Gene Set
Genes
44 genes differentially expressed following the CRCGN013_HEPG2_24H:M22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
6.63215
|
|
MYLK
|
myosin light chain kinase
|
4.89322
|
|
E2F2
|
E2F transcription factor 2
|
4.83812
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.31784
|
|
CHN1
|
chimerin 1
|
4.24602
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.67482
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.53972
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
3.41735
|
|
LCN2
|
lipocalin 2
|
3.35681
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.28728
|
|
EPHA3
|
EPH receptor A3
|
2.80826
|
|
JADE2
|
jade family PHD finger 2
|
2.79806
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.65735
|
|
EPN2
|
epsin 2
|
2.581
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.56268
|
|
GPATCH8
|
G patch domain containing 8
|
2.54267
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.41658
|
|
FOXJ1
|
forkhead box J1
|
2.07487
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLCD3A
|
TLC domain containing 3A
|
-5.27883
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.97986
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.68435
|
|
TUBB6
|
tubulin, beta 6 class V
|
-4.59569
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.45347
|
|
LDHD
|
lactate dehydrogenase D
|
-4.24458
|
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-4.11535
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.96969
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.27543
|
|
TRAPPC3
|
trafficking protein particle complex 3
|
-3.26827
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.24189
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.16672
|
|
AKR7A3
|
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
|
-2.92596
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.523
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.47057
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.42153
|
|
WRN
|
Werner syndrome, RecQ helicase-like
|
-2.41434
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.40161
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.34038
|
|
HMG20B
|
high mobility group 20B
|
-2.2763
|
|
CCNB2
|
cyclin B2
|
-2.12846
|
|
SH3GL2
|
SH3-domain GRB2-like 2
|
-2.08909
|
|
TLR4
|
toll-like receptor 4
|
-2.07006
|
|
PRUNE2
|
prune homolog 2 (Drosophila)
|
-2.06894
|
|
STX12
|
syntaxin 12
|
-2.05137
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.0379
|
