CRCGN013_HEPG2_24H:M23 Gene Set
Genes
35 genes differentially expressed following the CRCGN013_HEPG2_24H:M23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
5.23313
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.91482
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.82288
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.56921
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.36439
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.1973
|
|
MAP7
|
microtubule-associated protein 7
|
3.15922
|
|
CCNF
|
cyclin F
|
3.06187
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.96062
|
|
PRR15L
|
proline rich 15-like
|
2.82993
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
2.72254
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.30724
|
|
PARP2
|
poly (ADP-ribose) polymerase 2
|
2.30159
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.25514
|
|
CHN1
|
chimerin 1
|
2.18054
|
|
GPM6A
|
glycoprotein M6A
|
2.1127
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.01541
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.0014
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-9.42729
|
|
CCNB2
|
cyclin B2
|
-5.90832
|
|
GOLT1B
|
golgi transport 1B
|
-5.24435
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.16735
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.08663
|
|
LDHD
|
lactate dehydrogenase D
|
-3.73446
|
|
GDF15
|
growth differentiation factor 15
|
-3.70244
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.46018
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.29645
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.791
|
|
EGF
|
epidermal growth factor
|
-2.75864
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.66486
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.58785
|
|
SLC25A16
|
solute carrier family 25 (mitochondrial carrier), member 16
|
-2.19534
|
|
RLN1
|
relaxin 1
|
-2.11702
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.11417
|
|
WASHC4
|
WASH complex subunit 4
|
-2.10303
|
