CRCGN013_HEPG2_24H:M24 Gene Set
Genes
33 genes differentially expressed following the CRCGN013_HEPG2_24H:M24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
EVL
|
Enah/Vasp-like
|
6.59183
|
|
LCN2
|
lipocalin 2
|
5.34252
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.39598
|
|
CYCS
|
cytochrome c, somatic
|
4.16598
|
|
CHN1
|
chimerin 1
|
4.04601
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
3.98895
|
|
PRR15L
|
proline rich 15-like
|
3.87407
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.53352
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.53132
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
3.45265
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.41579
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.35612
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.33834
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.07171
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.23924
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.12427
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.11647
|
|
EGF
|
epidermal growth factor
|
2.0289
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-7.9101
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-6.67701
|
|
ZNF586
|
zinc finger protein 586
|
-5.05104
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.7327
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-4.46614
|
|
GDF15
|
growth differentiation factor 15
|
-3.45925
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.42747
|
|
GNAS
|
GNAS complex locus
|
-3.3873
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.18217
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.52908
|
|
ZNF146
|
zinc finger protein 146
|
-2.34567
|
|
CAPNS1
|
calpain, small subunit 1
|
-2.33183
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.31774
|
|
PDCD5
|
programmed cell death 5
|
-2.21359
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.06338
|