CRCGN013_HEPG2_24H:N01 Gene Set
Genes
47 genes differentially expressed following the CRCGN013_HEPG2_24H:N01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
9.08961
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
6.39071
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
5.89347
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.71299
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.63613
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
4.2914
|
|
LRP10
|
low density lipoprotein receptor-related protein 10
|
3.66108
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.53323
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
3.52287
|
|
SFTPB
|
surfactant protein B
|
3.33826
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
3.30287
|
|
MAP7
|
microtubule-associated protein 7
|
3.30157
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
3.2054
|
|
CHEK2
|
checkpoint kinase 2
|
3.19414
|
|
SERPINE1
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
|
2.79458
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.71745
|
|
UBR7
|
ubiquitin protein ligase E3 component n-recognin 7 (putative)
|
2.57343
|
|
STIMATE
|
STIM activating enhancer
|
2.48992
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.32546
|
|
TBP
|
TATA box binding protein
|
2.28413
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.26963
|
|
PLOD3
|
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
|
2.26291
|
|
CPVL
|
carboxypeptidase, vitellogenic-like
|
2.14809
|
|
PRKCH
|
protein kinase C, eta
|
2.14441
|
|
ANKRD17
|
ankyrin repeat domain 17
|
2.1275
|
|
RBKS
|
ribokinase
|
2.11067
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.37754
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.83298
|
|
CCNB2
|
cyclin B2
|
-4.55118
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.40507
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
-3.90052
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.84496
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
-3.71463
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.40528
|
|
ATP6V0B
|
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
|
-3.01468
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.92019
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.85171
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.74461
|
|
ZFP36
|
ZFP36 ring finger protein
|
-2.44213
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.32358
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.21215
|
|
PSME3IP1
|
proteasome activator subunit 3 interacting protein 1
|
-2.17676
|
|
CCNB1
|
cyclin B1
|
-2.13798
|
|
PPDPF
|
pancreatic progenitor cell differentiation and proliferation factor
|
-2.06777
|
|
TLR4
|
toll-like receptor 4
|
-2.05693
|
|
BCL2A1
|
BCL2-related protein A1
|
-2.02682
|
|
TAF1
|
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
|
-2.01142
|
