| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | chlorobenzene 19.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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54 genes differentially expressed following the CRCGN013_HEPG2_24H:N02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| E2F2 | E2F transcription factor 2 | 7.81536 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 7.50609 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.87233 |
| EPHA3 | EPH receptor A3 | 3.88347 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 3.04534 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.80186 |
| WASF3 | WAS protein family, member 3 | 2.79197 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.74935 |
| CCNF | cyclin F | 2.70286 |
| UBQLN2 | ubiquilin 2 | 2.6443 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.45067 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.34599 |
| GPATCH8 | G patch domain containing 8 | 2.31858 |
| EPHA5 | EPH receptor A5 | 2.30536 |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 | 2.26061 |
| KCNH1 | potassium channel, voltage gated eag related subfamily H, member 1 | 2.24064 |
| ZNF415 | zinc finger protein 415 | 2.2184 |
| SLC18A3 | solute carrier family 18 (vesicular acetylcholine transporter), member 3 | 2.18381 |
| CHMP6 | charged multivesicular body protein 6 | 2.11598 |
| DIPK1A | divergent protein kinase domain 1A | 2.10504 |
| GRTP1 | growth hormone regulated TBC protein 1 | 2.07832 |
| UNC119B | unc-119 homolog B (C. elegans) | 2.07646 |
| LOC122526780 | uncharacterized LOC122526780 | 2.06299 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.04859 |
| ITPKA | inositol-trisphosphate 3-kinase A | 2.02989 |
| H2BC6 | H2B clustered histone 6 | 2.02429 |
| B3GALT2 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 | 2.00954 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa | 2.00395 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NUP85 | nucleoporin 85kDa | -5.37793 |
| CCDC86 | coiled-coil domain containing 86 | -5.34393 |
| NRIP1 | nuclear receptor interacting protein 1 | -4.71161 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -3.85255 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.5699 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.36576 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.19607 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -2.92221 |
| RNF167 | ring finger protein 167 | -2.88123 |
| GRB2 | growth factor receptor-bound protein 2 | -2.71413 |
| KCTD2 | potassium channel tetramerization domain containing 2 | -2.6118 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | -2.58266 |
| PCNA | proliferating cell nuclear antigen | -2.5583 |
| PRPF19 | pre-mRNA processing factor 19 | -2.39025 |
| TUBB6 | tubulin, beta 6 class V | -2.35542 |
| MRPS7 | mitochondrial ribosomal protein S7 | -2.33113 |
| NT5C | 5', 3'-nucleotidase, cytosolic | -2.3258 |
| GAB2 | GRB2-associated binding protein 2 | -2.28931 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.2789 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -2.24406 |
| TEX10 | testis expressed 10 | -2.21206 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) | -2.19193 |
| MRPL58 | mitochondrial ribosomal protein L58 | -2.17827 |
| LDHD | lactate dehydrogenase D | -2.17532 |
| CCP110 | centriolar coiled coil protein 110kDa | -2.12045 |
| HEATR6 | HEAT repeat containing 6 | -2.03903 |
