| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | glutaraldehyde 19.4 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
64 genes differentially expressed following the CRCGN013_HEPG2_24H:N08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 6.39106 |
| CHMP6 | charged multivesicular body protein 6 | 5.81298 |
| AMDHD2 | amidohydrolase domain containing 2 | 5.80383 |
| NOTCH1 | notch 1 | 4.55453 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.50921 |
| SQOR | sulfide quinone oxidoreductase | 4.42436 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 4.19256 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.11475 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.06179 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 3.96893 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 3.82261 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.73791 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.62774 |
| SKIC2 | SKI2 subunit of superkiller complex | 3.41966 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 3.40232 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 3.17701 |
| CHN1 | chimerin 1 | 3.16646 |
| GATA3 | GATA binding protein 3 | 2.87574 |
| GATA2 | GATA binding protein 2 | 2.86911 |
| PFKL | phosphofructokinase, liver | 2.75608 |
| MVP | major vault protein | 2.68514 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 2.6341 |
| GPS1 | G protein pathway suppressor 1 | 2.60275 |
| ECD | ecdysoneless homolog (Drosophila) | 2.54409 |
| BZW2 | basic leucine zipper and W2 domains 2 | 2.54326 |
| CBR3 | carbonyl reductase 3 | 2.4115 |
| KLHL21 | kelch-like family member 21 | 2.33959 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.24956 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 2.23145 |
| UFM1 | ubiquitin-fold modifier 1 | 2.19401 |
| TAC4 | tachykinin 4 (hemokinin) | 2.16425 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.14362 |
| IFT88 | intraflagellar transport 88 | 2.07689 |
| GET3 | guided entry of tail-anchored proteins factor 3, ATPase | 2.04771 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.046 |
| COL18A1 | collagen, type XVIII, alpha 1 | 2.0315 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -6.1897 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -5.25222 |
| MAPK13 | mitogen-activated protein kinase 13 | -5.02987 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.48928 |
| FASTKD5 | FAST kinase domains 5 | -4.42875 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -4.24937 |
| LDHD | lactate dehydrogenase D | -4.22789 |
| ACOT9 | acyl-CoA thioesterase 9 | -4.0009 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.94364 |
| VAT1 | vesicle amine transport 1 | -3.80702 |
| TLCD3A | TLC domain containing 3A | -3.58131 |
| CCNB1 | cyclin B1 | -3.49 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -3.2261 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.20641 |
| TLR4 | toll-like receptor 4 | -3.11419 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.61734 |
| YME1L1 | YME1-like 1 ATPase | -2.60116 |
| GNAS | GNAS complex locus | -2.55712 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | -2.28355 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.26772 |
| RNF170 | ring finger protein 170 | -2.21343 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.18413 |
| HMG20B | high mobility group 20B | -2.18401 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 | -2.11325 |
| ATF5 | activating transcription factor 5 | -2.10945 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) | -2.10921 |
| OVOL2 | ovo-like zinc finger 2 | -2.06436 |
| UBE3C | ubiquitin protein ligase E3C | -2.02763 |
