CRCGN013_HEPG2_24H:N10 Gene Set
Genes
43 genes differentially expressed following the CRCGN013_HEPG2_24H:N10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
8.54595
|
|
CBR3
|
carbonyl reductase 3
|
6.72601
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
4.31725
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.21878
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
4.07503
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.78333
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
3.67477
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.40547
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.30949
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.20981
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.08038
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.05328
|
|
CHN1
|
chimerin 1
|
3.05102
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.96468
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.81013
|
|
EGF
|
epidermal growth factor
|
2.56741
|
|
PRR15L
|
proline rich 15-like
|
2.52567
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.36004
|
|
PRKCH
|
protein kinase C, eta
|
2.16995
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.14346
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.12771
|
|
F3
|
coagulation factor III (thromboplastin, tissue factor)
|
2.10345
|
|
DDAH1
|
dimethylarginine dimethylaminohydrolase 1
|
2.09842
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.02148
|
|
GAB2
|
GRB2-associated binding protein 2
|
2.00656
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.44007
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.54062
|
|
GNAS
|
GNAS complex locus
|
-4.638
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.02914
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.01855
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.63429
|
|
LAP3
|
leucine aminopeptidase 3
|
-3.53806
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.30671
|
|
CDC20
|
cell division cycle 20
|
-3.21733
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.55125
|
|
TLR4
|
toll-like receptor 4
|
-2.50084
|
|
PGAM4
|
phosphoglycerate mutase family member 4
|
-2.47424
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.45648
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.35471
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.30939
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.07391
|
|
ZMPSTE24
|
zinc metallopeptidase STE24
|
-2.07319
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.066
|
