| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | glutaraldehyde 2.42 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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63 genes differentially expressed following the CRCGN013_HEPG2_24H:N11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 9.03432 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 5.62706 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.44658 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.2864 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.2327 |
| PROS1 | protein S (alpha) | 3.95606 |
| MYLK | myosin light chain kinase | 3.91062 |
| SSBP2 | single-stranded DNA binding protein 2 | 3.87527 |
| LCN2 | lipocalin 2 | 3.86574 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.81756 |
| CHMP6 | charged multivesicular body protein 6 | 3.43965 |
| KLHL9 | kelch-like family member 9 | 3.27266 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.25559 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.2146 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.03591 |
| EPHA3 | EPH receptor A3 | 2.91756 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 2.86919 |
| LRP10 | low density lipoprotein receptor-related protein 10 | 2.82819 |
| EGF | epidermal growth factor | 2.75613 |
| H2BC12 | H2B clustered histone 12 | 2.74116 |
| RAB21 | RAB21, member RAS oncogene family | 2.66852 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | 2.43958 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.3953 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 | 2.36067 |
| MAP7 | microtubule-associated protein 7 | 2.34188 |
| SNX7 | sorting nexin 7 | 2.33309 |
| MSTN | myostatin | 2.27141 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 2.13005 |
| ZNF140 | zinc finger protein 140 | 2.11433 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | 2.11343 |
| PRDM13 | PR domain containing 13 | 2.06653 |
| QSER1 | glutamine and serine rich 1 | 2.03447 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| TLCD3A | TLC domain containing 3A | -6.73466 |
| NUP85 | nucleoporin 85kDa | -5.80115 |
| LDHD | lactate dehydrogenase D | -5.72766 |
| PCNA | proliferating cell nuclear antigen | -5.52743 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -5.42319 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -5.10653 |
| CCNB2 | cyclin B2 | -4.67061 |
| GNAS | GNAS complex locus | -3.62233 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.49136 |
| FAIM | Fas apoptotic inhibitory molecule | -3.30275 |
| SLC35F2 | solute carrier family 35, member F2 | -3.08426 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.05491 |
| IFRD2 | interferon-related developmental regulator 2 | -2.98186 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) | -2.72375 |
| DPP3 | dipeptidyl-peptidase 3 | -2.43012 |
| CCP110 | centriolar coiled coil protein 110kDa | -2.41764 |
| KCTD2 | potassium channel tetramerization domain containing 2 | -2.40384 |
| GLOD4 | glyoxalase domain containing 4 | -2.34697 |
| JPT1 | Jupiter microtubule associated homolog 1 | -2.22062 |
| CAB39 | calcium binding protein 39 | -2.21208 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -2.1979 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.18636 |
| SCAND1 | SCAN domain containing 1 | -2.17652 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.13672 |
| TPGS1 | tubulin polyglutamylase complex subunit 1 | -2.12825 |
| ARMC1 | armadillo repeat containing 1 | -2.10161 |
| CRYZ | crystallin, zeta (quinone reductase) | -2.08198 |
| COL9A1 | collagen, type IX, alpha 1 | -2.06208 |
| THBS4 | thrombospondin 4 | -2.04425 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.01604 |