CRCGN013_HEPG2_24H:N12 Gene Set
Genes
39 genes differentially expressed following the CRCGN013_HEPG2_24H:N12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MYLK
|
myosin light chain kinase
|
6.38675
|
|
CYCS
|
cytochrome c, somatic
|
3.47958
|
|
STIMATE
|
STIM activating enhancer
|
3.18843
|
|
METRN
|
meteorin, glial cell differentiation regulator
|
3.1653
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.11924
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.10265
|
|
LCN2
|
lipocalin 2
|
3.00561
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.84886
|
|
CHN1
|
chimerin 1
|
2.75259
|
|
SLC75A1
|
solute carrier family 75 member 1
|
2.64671
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.63022
|
|
WASF3
|
WAS protein family, member 3
|
2.62874
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.60967
|
|
EGF
|
epidermal growth factor
|
2.31253
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.26417
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.18752
|
|
SIRT3
|
sirtuin 3
|
2.02009
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-6.89588
|
|
LDHD
|
lactate dehydrogenase D
|
-6.23307
|
|
GNAS
|
GNAS complex locus
|
-5.30972
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.99838
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.95958
|
|
DUSP6
|
dual specificity phosphatase 6
|
-3.64414
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.54398
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.20128
|
|
CD320
|
CD320 molecule
|
-3.04976
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.02071
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.88618
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.76581
|
|
CDC20
|
cell division cycle 20
|
-2.75824
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
-2.58379
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-2.56547
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.53944
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.43868
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.31858
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.27544
|
|
ZW10
|
zw10 kinetochore protein
|
-2.20977
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.1907
|
|
CCNB2
|
cyclin B2
|
-2.10476
|
