| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | vorinostat 0.67 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
94 genes differentially expressed following the CRCGN013_HEPG2_24H:N18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 9.03796 |
| STIMATE | STIM activating enhancer | 6.37784 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 6.0234 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 4.94538 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.77001 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 4.43261 |
| NOTCH1 | notch 1 | 4.04963 |
| FOXO4 | forkhead box O4 | 3.80602 |
| PLS1 | plastin 1 | 3.63575 |
| DNM1 | dynamin 1 | 3.42445 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.42378 |
| STK10 | serine/threonine kinase 10 | 3.41984 |
| SKIC2 | SKI2 subunit of superkiller complex | 3.30904 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 3.26451 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.24225 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.14749 |
| MVP | major vault protein | 3.13849 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 3.12906 |
| CBR1 | carbonyl reductase 1 | 2.85455 |
| FPGS | folylpolyglutamate synthase | 2.84581 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 2.8336 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.79433 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 2.70563 |
| FZD7 | frizzled class receptor 7 | 2.65426 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | 2.63276 |
| S100A4 | S100 calcium binding protein A4 | 2.62176 |
| LCN2 | lipocalin 2 | 2.59907 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.54536 |
| PRCP | prolylcarboxypeptidase (angiotensinase C) | 2.47522 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 2.38465 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | 2.35946 |
| USP6NL | USP6 N-terminal like | 2.35075 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.29689 |
| EGF | epidermal growth factor | 2.29022 |
| ELOVL6 | ELOVL fatty acid elongase 6 | 2.26627 |
| TBC1D31 | TBC1 domain family, member 31 | 2.16723 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 2.16 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) | 2.13254 |
| DENND2D | DENN/MADD domain containing 2D | 2.12257 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.11618 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 2.11407 |
| SULF1 | sulfatase 1 | 2.09635 |
| STXBP1 | syntaxin binding protein 1 | 2.0749 |
| FUBP3 | far upstream element (FUSE) binding protein 3 | 2.06618 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.0617 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.04271 |
| GPR137B | G protein-coupled receptor 137B | 2.03495 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.01603 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ISOC1 | isochorismatase domain containing 1 | -6.63695 |
| ICAM3 | intercellular adhesion molecule 3 | -5.27553 |
| GNAS | GNAS complex locus | -5.06121 |
| CCNB2 | cyclin B2 | -4.95818 |
| DERA | deoxyribose-phosphate aldolase (putative) | -4.75871 |
| ADI1 | acireductone dioxygenase 1 | -4.20795 |
| CCDC86 | coiled-coil domain containing 86 | -3.98772 |
| HMG20B | high mobility group 20B | -3.9288 |
| TCTN1 | tectonic family member 1 | -3.89394 |
| CD320 | CD320 molecule | -3.88619 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.75694 |
| DNM1L | dynamin 1-like | -3.56765 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.45979 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.42529 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.37425 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -3.37067 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.2697 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -3.23219 |
| TRIB3 | tribbles pseudokinase 3 | -3.20307 |
| TLCD3A | TLC domain containing 3A | -3.13737 |
| FAIM | Fas apoptotic inhibitory molecule | -2.90682 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -2.89194 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.78285 |
| ILK | integrin-linked kinase | -2.70194 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -2.67836 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | -2.64849 |
| KEAP1 | kelch-like ECH-associated protein 1 | -2.61744 |
| PCNA | proliferating cell nuclear antigen | -2.54808 |
| STAMBP | STAM binding protein | -2.43882 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -2.4184 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 | -2.28762 |
| SPAG7 | sperm associated antigen 7 | -2.28281 |
| BCL7B | B-cell CLL/lymphoma 7B | -2.26842 |
| CCNB1 | cyclin B1 | -2.2445 |
| STAP2 | signal transducing adaptor family member 2 | -2.20412 |
| TMEM109 | transmembrane protein 109 | -2.20287 |
| ADSS2 | adenylosuccinate synthase 2 | -2.20009 |
| MYLK | myosin light chain kinase | -2.11979 |
| PNKP | polynucleotide kinase 3'-phosphatase | -2.10453 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.06806 |
| LRRC41 | leucine rich repeat containing 41 | -2.0654 |
| SLBP | stem-loop binding protein | -2.06519 |
| CASC3 | cancer susceptibility candidate 3 | -2.0621 |
| TATDN2 | TatD DNase domain containing 2 | -2.05248 |
| CCNA2 | cyclin A2 | -2.04005 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -2.03904 |
