CRCGN013_HEPG2_24H:N19 Gene Set
Genes
36 genes differentially expressed following the CRCGN013_HEPG2_24H:N19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.75776
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
4.71304
|
|
UBQLN2
|
ubiquilin 2
|
3.80723
|
|
ZNF589
|
zinc finger protein 589
|
3.75613
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.73159
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.3478
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.15745
|
|
GPATCH8
|
G patch domain containing 8
|
3.13177
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.12561
|
|
CEP57
|
centrosomal protein 57kDa
|
3.06564
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.65593
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.64681
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.60449
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.45046
|
|
NOTCH1
|
notch 1
|
2.40128
|
|
SCRN1
|
secernin 1
|
2.19851
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.08309
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-7.66083
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.62756
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.58066
|
|
LDHD
|
lactate dehydrogenase D
|
-3.521
|
|
MAP7
|
microtubule-associated protein 7
|
-3.50435
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.49558
|
|
EGF
|
epidermal growth factor
|
-3.46193
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.39823
|
|
ZNF586
|
zinc finger protein 586
|
-3.05112
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.02416
|
|
GNAS
|
GNAS complex locus
|
-2.76944
|
|
RPS5
|
ribosomal protein S5
|
-2.67361
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.65052
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.59913
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.2899
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.20252
|
|
WASHC4
|
WASH complex subunit 4
|
-2.03955
|
|
DUSP13A
|
dual specificity phosphatase 13A
|
-2.03302
|
|
OAT
|
ornithine aminotransferase
|
-2.02925
|
