CRCGN013_HEPG2_24H:N20 Gene Set
Genes
40 genes differentially expressed following the CRCGN013_HEPG2_24H:N20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.54513
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.94466
|
|
UBQLN2
|
ubiquilin 2
|
4.56321
|
|
ABHD6
|
abhydrolase domain containing 6
|
4.15892
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
4.04415
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.93386
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.66604
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.14879
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.10407
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.00064
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
2.86492
|
|
LCN2
|
lipocalin 2
|
2.8473
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
2.81342
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.79063
|
|
STK10
|
serine/threonine kinase 10
|
2.72838
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.62873
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.55337
|
|
MYLK
|
myosin light chain kinase
|
2.49342
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.43964
|
|
LRP10
|
low density lipoprotein receptor-related protein 10
|
2.29064
|
|
HOXA10
|
homeobox A10
|
2.22599
|
|
EPHB2
|
EPH receptor B2
|
2.15946
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.14914
|
|
VGLL4
|
vestigial-like family member 4
|
2.12023
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-8.64
|
|
ZNF586
|
zinc finger protein 586
|
-3.76327
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-3.27865
|
|
EXT1
|
exostosin glycosyltransferase 1
|
-2.86647
|
|
LDHD
|
lactate dehydrogenase D
|
-2.86629
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.58135
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.50575
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.48846
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.35243
|
|
CCNB2
|
cyclin B2
|
-2.34285
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.33455
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.25032
|
|
EGF
|
epidermal growth factor
|
-2.12621
|
|
FBXO7
|
F-box protein 7
|
-2.08514
|
|
ZNF134
|
zinc finger protein 134
|
-2.08478
|
|
ZNF587B
|
zinc finger protein 587B
|
-2.0529
|
