CRCGN013_HEPG2_24H:N22 Gene Set
Genes
41 genes differentially expressed following the CRCGN013_HEPG2_24H:N22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
7.33134
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
3.70031
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.61117
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.47287
|
|
STIMATE
|
STIM activating enhancer
|
3.43189
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.41847
|
|
EVL
|
Enah/Vasp-like
|
3.40334
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.388
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.8216
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.73324
|
|
UBQLN2
|
ubiquilin 2
|
2.59634
|
|
PLS1
|
plastin 1
|
2.58018
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.57153
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.55873
|
|
UBE2A
|
ubiquitin-conjugating enzyme E2A
|
2.35898
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.34502
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.28071
|
|
KIF20A
|
kinesin family member 20A
|
2.25026
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.13622
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.12034
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.11481
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.15358
|
|
GNAS
|
GNAS complex locus
|
-5.50738
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-5.00623
|
|
LDHD
|
lactate dehydrogenase D
|
-3.70273
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.45956
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.29373
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.18394
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.10771
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.83575
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.72578
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.689
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.64535
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.63329
|
|
HMG20B
|
high mobility group 20B
|
-2.60061
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.54756
|
|
DNM1L
|
dynamin 1-like
|
-2.53252
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.24355
|
|
CDC20
|
cell division cycle 20
|
-2.19326
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.16234
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.01399
|
