CRCGN013_HEPG2_24H:N23 Gene Set
Genes
42 genes differentially expressed following the CRCGN013_HEPG2_24H:N23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
6.0908
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
5.46687
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
5.32124
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.95792
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.86854
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.84583
|
|
EVL
|
Enah/Vasp-like
|
3.34806
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.82175
|
|
SFTPB
|
surfactant protein B
|
2.80977
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.7615
|
|
EGF
|
epidermal growth factor
|
2.70112
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.68629
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
2.59766
|
|
PRKCH
|
protein kinase C, eta
|
2.54154
|
|
CHN1
|
chimerin 1
|
2.48426
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.41093
|
|
ALG8
|
ALG8, alpha-1,3-glucosyltransferase
|
2.29404
|
|
KIF5C
|
kinesin family member 5C
|
2.23528
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.09129
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.05944
|
|
SLC6A3
|
solute carrier family 6 (neurotransmitter transporter), member 3
|
2.04448
|
|
PKN1
|
protein kinase N1
|
2.0345
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.82712
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.59386
|
|
LAP3
|
leucine aminopeptidase 3
|
-4.37783
|
|
GNAS
|
GNAS complex locus
|
-4.07955
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.06693
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.96898
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.94652
|
|
LDHD
|
lactate dehydrogenase D
|
-3.77564
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.7266
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.33296
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.29535
|
|
HEATR1
|
HEAT repeat containing 1
|
-3.07893
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.00936
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.66448
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.38788
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.27154
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-2.23297
|
|
CCNB2
|
cyclin B2
|
-2.22965
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.16377
|
|
CCNB1
|
cyclin B1
|
-2.00395
|
