CRCGN013_HEPG2_24H:N24 Gene Set
Genes
41 genes differentially expressed following the CRCGN013_HEPG2_24H:N24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.33432
|
|
NOTCH1
|
notch 1
|
4.12076
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.62672
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.56416
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.53783
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.23768
|
|
PLSCR3
|
phospholipid scramblase 3
|
3.18413
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.04144
|
|
LCN2
|
lipocalin 2
|
3.03659
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.85823
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.79305
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.67601
|
|
EVL
|
Enah/Vasp-like
|
2.62021
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.61522
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.54128
|
|
SLC35A3
|
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
|
2.46901
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.25746
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.24141
|
|
RAB31
|
RAB31, member RAS oncogene family
|
2.06477
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
2.04057
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.03774
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.20584
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.4885
|
|
CCNB2
|
cyclin B2
|
-3.98126
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.79952
|
|
CCNB1
|
cyclin B1
|
-3.23368
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.19144
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.12158
|
|
CD320
|
CD320 molecule
|
-2.77141
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.69576
|
|
LDHD
|
lactate dehydrogenase D
|
-2.64886
|
|
ABCF1
|
ATP-binding cassette, sub-family F (GCN20), member 1
|
-2.35253
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.34145
|
|
NISCH
|
nischarin
|
-2.33366
|
|
GNAS
|
GNAS complex locus
|
-2.24112
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.24084
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
-2.21082
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.09241
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.0614
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.01596
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.00818
|
