CRCGN013_HEPG2_24H:O07 Gene Set
Genes
42 genes differentially expressed following the CRCGN013_HEPG2_24H:O07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.9046
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
4.56495
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.4287
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.2321
|
|
CHN1
|
chimerin 1
|
3.07353
|
|
NOTCH1
|
notch 1
|
2.9508
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.78618
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.77203
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.6347
|
|
MAP7
|
microtubule-associated protein 7
|
2.55642
|
|
GATA2
|
GATA binding protein 2
|
2.39123
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.38523
|
|
CREB1
|
cAMP responsive element binding protein 1
|
2.28533
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.18942
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
2.13637
|
|
EVL
|
Enah/Vasp-like
|
2.10707
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.07857
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.06413
|
|
RALGDS
|
ral guanine nucleotide dissociation stimulator
|
2.05293
|
|
PLS1
|
plastin 1
|
2.04047
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.02182
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.89477
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.08187
|
|
CAB39
|
calcium binding protein 39
|
-3.48663
|
|
GDF15
|
growth differentiation factor 15
|
-3.33333
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.07743
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.04157
|
|
LDHD
|
lactate dehydrogenase D
|
-2.96353
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.81297
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.57117
|
|
S100A4
|
S100 calcium binding protein A4
|
-2.5399
|
|
CCNB2
|
cyclin B2
|
-2.5285
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.5184
|
|
GNAS
|
GNAS complex locus
|
-2.38277
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.31695
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.27593
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.20877
|
|
ZW10
|
zw10 kinetochore protein
|
-2.1814
|
|
EAPP
|
E2F-associated phosphoprotein
|
-2.14317
|
|
GMFG
|
glia maturation factor, gamma
|
-2.10937
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.0136
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.00033
|
