CRCGN013_HEPG2_24H:O08 Gene Set
Genes
44 genes differentially expressed following the CRCGN013_HEPG2_24H:O08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
5.44895
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
5.19623
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.02676
|
|
TATDN2
|
TatD DNase domain containing 2
|
4.93376
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.90517
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.34805
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.19739
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
4.11089
|
|
STK10
|
serine/threonine kinase 10
|
3.60785
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.56295
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.4728
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.92271
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.80808
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.78851
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.56979
|
|
ZNF589
|
zinc finger protein 589
|
2.38194
|
|
SMAD3
|
SMAD family member 3
|
2.31509
|
|
IGHMBP2
|
immunoglobulin mu binding protein 2
|
2.23542
|
|
SETD5
|
SET domain containing 5
|
2.18496
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.17601
|
|
WDR91
|
WD repeat domain 91
|
2.07805
|
|
CYCS
|
cytochrome c, somatic
|
2.04785
|
|
MOK
|
MOK protein kinase
|
2.04205
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
2.02072
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.98973
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.7702
|
|
CD320
|
CD320 molecule
|
-4.76708
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.53958
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.36693
|
|
LDHD
|
lactate dehydrogenase D
|
-4.10092
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
-4.09338
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.80969
|
|
ZNF586
|
zinc finger protein 586
|
-3.77599
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.635
|
|
G3BP1
|
GTPase activating protein (SH3 domain) binding protein 1
|
-3.63365
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.35404
|
|
MAP7
|
microtubule-associated protein 7
|
-3.0221
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.85408
|
|
GNAS
|
GNAS complex locus
|
-2.70327
|
|
EGF
|
epidermal growth factor
|
-2.65298
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.24934
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.21477
|
|
WASHC4
|
WASH complex subunit 4
|
-2.10994
|
|
SENP6
|
SUMO1/sentrin specific peptidase 6
|
-2.01948
|
